AP2B.H13CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	AP2B.H13CORE.0.SM.B
Gene (human)	TFAP2B (GeneCards)
Gene synonyms (human)
Gene (mouse)	Tfap2b
Gene synonyms (mouse)	Tcfap2b
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	18
Consensus	ddnSCCYvRGGSndhdhn
GC content	57.72%
Information content (bits; total / per base)	10.857 / 0.603
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9846
Previous names	AP2B.H12CORE.0.SM.B

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.977	0.959	0.949	0.915	0.928	0.891
Overall, 3 experiments	best	0.993	0.989	0.965	0.944	0.935	0.91
Methyl HT-SELEX, 1 experiments	median	0.977	0.959	0.965	0.944	0.935	0.91
Methyl HT-SELEX, 1 experiments	best	0.977	0.959	0.965	0.944	0.935	0.91
Non-Methyl HT-SELEX, 2 experiments	median	0.976	0.959	0.893	0.886	0.786	0.797
Non-Methyl HT-SELEX, 2 experiments	best	0.993	0.989	0.949	0.915	0.928	0.891

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-span-helix factors (bHSH) {1.3} (TFClass)
TF family	AP-2 {1.3.1} (TFClass)
TF subfamily	{1.3.1.0} (TFClass)
TFClass ID	TFClass: 1.3.1.0.2
HGNC	HGNC:11743
MGI	MGI:104672
EntrezGene (human)	GeneID:7021 (SSTAR profile)
EntrezGene (mouse)	GeneID:21419 (SSTAR profile)
UniProt ID (human)	AP2B_HUMAN
UniProt ID (mouse)	AP2B_MOUSE
UniProt AC (human)	Q92481 (TFClass)
UniProt AC (mouse)	Q61313 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	AP2B.H13CORE.0.SM.B.pcm
PWM	AP2B.H13CORE.0.SM.B.pwm
PFM	AP2B.H13CORE.0.SM.B.pfm
Threshold to P-value map	AP2B.H13CORE.0.SM.B.thr
Motif in other formats
JASPAR format	AP2B.H13CORE.0.SM.B_jaspar_format.txt
MEME format	AP2B.H13CORE.0.SM.B_meme_format.meme
Transfac format	AP2B.H13CORE.0.SM.B_transfac_format.txt
Homer format	AP2B.H13CORE.0.SM.B_homer_format_0.001.txt AP2B.H13CORE.0.SM.B_homer_format_0.0005.txt AP2B.H13CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	5421.0	1171.0	1550.0	1704.0
02	3467.25	1288.25	1557.25	3533.25
03	2868.0	2462.0	1759.0	2757.0
04	355.0	2566.0	6589.0	336.0
05	156.0	9301.0	196.0	193.0
06	145.0	8812.0	193.0	696.0
07	163.0	2473.0	1099.0	6111.0
08	1049.0	3719.0	4133.0	945.0
09	5720.0	767.0	3308.0	51.0
10	629.0	19.0	9175.0	23.0
11	79.0	49.0	9661.0	57.0
12	253.0	4592.0	4627.0	374.0
13	2008.0	3206.0	2688.0	1944.0
14	5554.0	901.0	1693.0	1698.0
15	2556.0	1464.0	1065.0	4761.0
16	2846.0	1085.0	1774.0	4141.0
17	2173.25	1761.25	1448.25	4463.25
18	2534.0	1996.0	2143.0	3173.0

PFM

	A	C	G	T
01	0.551	0.119	0.157	0.173
02	0.352	0.131	0.158	0.359
03	0.291	0.25	0.179	0.28
04	0.036	0.261	0.669	0.034
05	0.016	0.945	0.02	0.02
06	0.015	0.895	0.02	0.071
07	0.017	0.251	0.112	0.621
08	0.107	0.378	0.42	0.096
09	0.581	0.078	0.336	0.005
10	0.064	0.002	0.932	0.002
11	0.008	0.005	0.981	0.006
12	0.026	0.466	0.47	0.038
13	0.204	0.326	0.273	0.197
14	0.564	0.092	0.172	0.172
15	0.26	0.149	0.108	0.484
16	0.289	0.11	0.18	0.421
17	0.221	0.179	0.147	0.453
18	0.257	0.203	0.218	0.322

PWM

	A	C	G	T
01	0.789	-0.742	-0.462	-0.367
02	0.342	-0.647	-0.457	0.361
03	0.153	0.0	-0.336	0.113
04	-1.931	0.042	0.984	-1.986
05	-2.745	1.329	-2.52	-2.535
06	-2.817	1.275	-2.535	-1.261
07	-2.702	0.005	-0.805	0.909
08	-0.852	0.412	0.518	-0.956
09	0.843	-1.164	0.295	-3.834
10	-1.362	-4.751	1.315	-4.579
11	-3.411	-3.872	1.367	-3.727
12	-2.267	0.623	0.631	-1.879
13	-0.203	0.264	0.088	-0.236
14	0.813	-1.003	-0.374	-0.371
15	0.038	-0.519	-0.837	0.659
16	0.145	-0.818	-0.327	0.52
17	-0.124	-0.334	-0.53	0.595
18	0.029	-0.209	-0.138	0.254

Standard thresholds

P-value	Threshold
0.001	4.49076
0.0005	5.42611
0.0001	7.31656