BARH2.H13INVIVO.0.SM.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	BARH2.H13INVIVO.0.SM.D
Gene (human)	BARHL2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Barhl2
Gene synonyms (mouse)	Barh1, Mbh1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	12
Consensus	ndnCRWTTARnn
GC content	39.15%
Information content (bits; total / per base)	9.703 / 0.809
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	8912
Previous names	BARH2.H12INVIVO.0.SM.D

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.966	0.946	0.942	0.91	0.912	0.876
Overall, 8 experiments	best	0.994	0.989	0.986	0.979	0.972	0.96
Methyl HT-SELEX, 2 experiments	median	0.98	0.967	0.966	0.948	0.942	0.919
Methyl HT-SELEX, 2 experiments	best	0.994	0.989	0.986	0.979	0.967	0.954
Non-Methyl HT-SELEX, 6 experiments	median	0.961	0.937	0.933	0.902	0.866	0.84
Non-Methyl HT-SELEX, 6 experiments	best	0.992	0.987	0.986	0.978	0.972	0.96

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Homeo domain factors {3.1} (TFClass)
TF family	NK-related {3.1.2} (TFClass)
TF subfamily	BARHL {3.1.2.1} (TFClass)
TFClass ID	TFClass: 3.1.2.1.2
HGNC	HGNC:954
MGI	MGI:1859314
EntrezGene (human)	GeneID:343472 (SSTAR profile)
EntrezGene (mouse)	GeneID:104382 (SSTAR profile)
UniProt ID (human)	BARH2_HUMAN
UniProt ID (mouse)	BARH2_MOUSE
UniProt AC (human)	Q9NY43 (TFClass)
UniProt AC (mouse)	Q8VIB5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	6
Methyl-HT-SELEX	2
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	BARH2.H13INVIVO.0.SM.D.pcm
PWM	BARH2.H13INVIVO.0.SM.D.pwm
PFM	BARH2.H13INVIVO.0.SM.D.pfm
Threshold to P-value map	BARH2.H13INVIVO.0.SM.D.thr
Motif in other formats
JASPAR format	BARH2.H13INVIVO.0.SM.D_jaspar_format.txt
MEME format	BARH2.H13INVIVO.0.SM.D_meme_format.meme
Transfac format	BARH2.H13INVIVO.0.SM.D_transfac_format.txt
Homer format	BARH2.H13INVIVO.0.SM.D_homer_format_0.001.txt BARH2.H13INVIVO.0.SM.D_homer_format_0.0005.txt BARH2.H13INVIVO.0.SM.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2238.75	2028.75	2617.75	2026.75
02	3701.0	1446.0	2269.0	1496.0
03	1735.0	2970.0	2216.0	1991.0
04	138.0	7994.0	63.0	717.0
05	4558.0	660.0	3639.0	55.0
06	5182.0	121.0	3.0	3606.0
07	0.0	0.0	0.0	8912.0
08	0.0	0.0	0.0	8912.0
09	8890.0	0.0	21.0	1.0
10	2609.0	506.0	5048.0	749.0
11	1281.0	3009.0	2433.0	2189.0
12	2323.0	1885.0	2936.0	1768.0

PFM

	A	C	G	T
01	0.251	0.228	0.294	0.227
02	0.415	0.162	0.255	0.168
03	0.195	0.333	0.249	0.223
04	0.015	0.897	0.007	0.08
05	0.511	0.074	0.408	0.006
06	0.581	0.014	0.0	0.405
07	0.0	0.0	0.0	1.0
08	0.0	0.0	0.0	1.0
09	0.998	0.0	0.002	0.0
10	0.293	0.057	0.566	0.084
11	0.144	0.338	0.273	0.246
12	0.261	0.212	0.329	0.198

PWM

	A	C	G	T
01	0.005	-0.094	0.161	-0.095
02	0.507	-0.432	0.018	-0.398
03	-0.25	0.287	-0.005	-0.112
04	-2.766	1.277	-3.531	-1.132
05	0.715	-1.214	0.49	-3.662
06	0.844	-2.895	-6.047	0.481
07	-6.888	-6.888	-6.888	1.386
08	-6.888	-6.888	-6.888	1.386
09	1.383	-6.888	-4.563	-6.524
10	0.158	-1.479	0.817	-1.088
11	-0.553	0.3	0.088	-0.018
12	0.042	-0.167	0.276	-0.231

Standard thresholds

P-value	Threshold
0.001	5.14931
0.0005	6.162125
0.0001	7.606025