MotifBCL6.H13CORE.0.PSM.A
Gene (human)BCL6
(GeneCards)
Gene synonyms (human)BCL5, LAZ3, ZBTB27, ZNF51
Gene (mouse)Bcl6
Gene synonyms (mouse)Bcl-6
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length16
ConsensusnhGCTTTCKAGGAAYn
GC content44.37%
Information content (bits; total / per base)20.273 / 1.267
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words7198
Previous namesBCL6.H12CORE.0.PSM.A

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 10 (67) 0.794 0.933 0.745 0.928 0.762 0.931 3.026 5.63 116.824 680.959
Mouse 15 (93) 0.816 0.97 0.745 0.929 0.801 0.964 3.076 4.837 101.585 213.244

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 1.0 1.0 0.973 0.974 0.82 0.847
best 1.0 1.0 0.998 0.998 0.896 0.908
Methyl HT-SELEX, 1 experiments median 1.0 1.0 0.998 0.998 0.896 0.908
best 1.0 1.0 0.998 0.998 0.896 0.908
Non-Methyl HT-SELEX, 1 experiments median 1.0 1.0 0.948 0.949 0.743 0.785
best 1.0 1.0 0.948 0.949 0.743 0.785

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 10.132 3.449 0.406 0.257
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyMore than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamilyBCL6 {2.3.3.22} (TFClass)
TFClass IDTFClass: 2.3.3.22.2
HGNCHGNC:1001
MGIMGI:107187
EntrezGene (human)GeneID:604
(SSTAR profile)
EntrezGene (mouse)GeneID:12053
(SSTAR profile)
UniProt ID (human)BCL6_HUMAN
UniProt ID (mouse)BCL6_MOUSE
UniProt AC (human)P41182
(TFClass)
UniProt AC (mouse)P41183
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 10 human, 15 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
012234.51536.51739.51687.5
02913.252029.25790.253465.25
03850.0142.05814.0392.0
04116.06848.082.0152.0
05383.0103.037.06675.0
06269.0376.0277.06276.0
074.02.01.07191.0
080.07189.00.09.0
0918.0381.04399.02400.0
107168.07.07.016.0
1154.01.07137.06.0
129.011.07149.029.0
136900.030.0173.095.0
146920.024.040.0214.0
151359.01552.0182.04105.0
161515.751347.751693.752640.75
PFM
ACGT
010.310.2130.2420.234
020.1270.2820.110.481
030.1180.020.8080.054
040.0160.9510.0110.021
050.0530.0140.0050.927
060.0370.0520.0380.872
070.0010.00.00.999
080.00.9990.00.001
090.0030.0530.6110.333
100.9960.0010.0010.002
110.0080.00.9920.001
120.0010.0020.9930.004
130.9590.0040.0240.013
140.9610.0030.0060.03
150.1890.2160.0250.57
160.2110.1870.2350.367
PWM
ACGT
010.216-0.158-0.034-0.064
02-0.6770.12-0.8210.655
03-0.749-2.5251.172-1.52
04-2.7241.336-3.063-2.458
05-1.543-2.84-3.8271.31
06-1.894-1.561-1.8641.248
07-5.669-6.057-6.3271.384
08-6.6991.384-6.699-5.079
09-4.49-1.5480.8930.288
101.381-5.275-5.275-4.594
11-3.467-6.3271.377-5.39
12-5.079-4.9151.379-4.055
131.343-4.024-2.33-2.92
141.346-4.23-3.754-2.12
15-0.28-0.148-2.280.824
16-0.171-0.289-0.060.383
Standard thresholds
P-value Threshold
0.001 -2.03654
0.0005 -0.26699
0.0001 3.44896