CEBPG.H13INVIVO.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	CEBPG.H13INVIVO.1.SM.B
Gene (human)	CEBPG (GeneCards)
Gene synonyms (human)
Gene (mouse)	Cebpg
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	11
Consensus	nRTTGCGYhRn
GC content	48.08%
Information content (bits; total / per base)	10.592 / 0.963
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	8956
Previous names	CEBPG.H12INVIVO.1.SM.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.959	0.983	0.925	0.963	0.926	0.951	4.146	4.599	635.469	964.886
Mouse	1 (7)	0.918	0.922	0.871	0.876	0.828	0.831	2.639	2.675	471.013	541.432

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 8 experiments	median	0.979	0.965	0.958	0.938	0.854	0.852
Overall, 8 experiments	best	0.998	0.997	0.996	0.993	0.984	0.979
Methyl HT-SELEX, 2 experiments	median	0.99	0.982	0.979	0.969	0.949	0.936
Methyl HT-SELEX, 2 experiments	best	0.997	0.995	0.996	0.993	0.984	0.979
Non-Methyl HT-SELEX, 6 experiments	median	0.956	0.945	0.862	0.855	0.716	0.745
Non-Methyl HT-SELEX, 6 experiments	best	0.998	0.997	0.992	0.988	0.978	0.97

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	8.358	10.448	0.36	0.231

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	C/EBP-related {1.1.8} (TFClass)
TF subfamily	CEBP {1.1.8.1} (TFClass)
TFClass ID	TFClass: 1.1.8.1.3
HGNC	HGNC:1837
MGI	MGI:104982
EntrezGene (human)	GeneID:1054 (SSTAR profile)
EntrezGene (mouse)	GeneID:12611 (SSTAR profile)
UniProt ID (human)	CEBPG_HUMAN
UniProt ID (mouse)	CEBPG_MOUSE
UniProt AC (human)	P53567 (TFClass)
UniProt AC (mouse)	P53568 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 1 mouse
HT-SELEX	6
Methyl-HT-SELEX	2
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	CEBPG.H13INVIVO.1.SM.B.pcm
PWM	CEBPG.H13INVIVO.1.SM.B.pwm
PFM	CEBPG.H13INVIVO.1.SM.B.pfm
Threshold to P-value map	CEBPG.H13INVIVO.1.SM.B.thr
Motif in other formats
JASPAR format	CEBPG.H13INVIVO.1.SM.B_jaspar_format.txt
MEME format	CEBPG.H13INVIVO.1.SM.B_meme_format.meme
Transfac format	CEBPG.H13INVIVO.1.SM.B_transfac_format.txt
Homer format	CEBPG.H13INVIVO.1.SM.B_homer_format_0.001.txt CEBPG.H13INVIVO.1.SM.B_homer_format_0.0005.txt CEBPG.H13INVIVO.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1143.0	2858.0	2696.0	2259.0
02	4304.0	1002.0	3631.0	19.0
03	0.0	0.0	0.0	8956.0
04	0.0	0.0	0.0	8956.0
05	921.0	0.0	8034.0	1.0
06	16.0	8926.0	13.0	1.0
07	1205.0	436.0	7144.0	171.0
08	1485.0	2025.0	221.0	5225.0
09	4512.0	2280.0	940.0	1224.0
10	6066.25	728.25	1281.25	880.25
11	1273.0	2830.0	2318.0	2535.0

PFM

	A	C	G	T
01	0.128	0.319	0.301	0.252
02	0.481	0.112	0.405	0.002
03	0.0	0.0	0.0	1.0
04	0.0	0.0	0.0	1.0
05	0.103	0.0	0.897	0.0
06	0.002	0.997	0.001	0.0
07	0.135	0.049	0.798	0.019
08	0.166	0.226	0.025	0.583
09	0.504	0.255	0.105	0.137
10	0.677	0.081	0.143	0.098
11	0.142	0.316	0.259	0.283

PWM

	A	C	G	T
01	-0.671	0.244	0.186	0.009
02	0.653	-0.803	0.483	-4.657
03	-6.893	-6.893	-6.893	1.386
04	-6.893	-6.893	-6.893	1.386
05	-0.887	-6.893	1.277	-6.528
06	-4.809	1.382	-4.989	-6.528
07	-0.619	-1.632	1.16	-2.56
08	-0.41	-0.1	-2.306	0.847
09	0.7	0.018	-0.867	-0.603
10	0.996	-1.121	-0.557	-0.932
11	-0.564	0.234	0.035	0.124

Standard thresholds

P-value	Threshold
0.001	4.781585
0.0005	5.804885
0.0001	7.53915