COT2.H13INVITRO.1.P.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	COT2.H13INVITRO.1.P.D
Gene (human)	NR2F2 (GeneCards)
Gene synonyms (human)	ARP1, TFCOUP2
Gene (mouse)	Nr2f2
Gene synonyms (mouse)	Aporp1, Arp-1, Arp1, Tfcoup2
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	D

Motif length	12
Consensus	bvRRGGTCAvvd
GC content	56.24%
Information content (bits; total / per base)	10.421 / 0.868
Data sources	ChIP-Seq
Aligned words	582
Previous names	COT2.H12INVITRO.1.P.D

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	11 (75)	0.81	0.877	0.672	0.758	0.802	0.882	2.448	3.119	137.602	242.658
Mouse	1 (7)	0.731	0.751	0.631	0.656	0.712	0.735	2.319	2.452	66.041	96.102

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Nuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF family	RXR-related receptors {2.1.3} (TFClass)
TF subfamily	COUP (NR2F) {2.1.3.5} (TFClass)
TFClass ID	TFClass: 2.1.3.5.2
HGNC	HGNC:7976
MGI	MGI:1352452
EntrezGene (human)	GeneID:7026 (SSTAR profile)
EntrezGene (mouse)	GeneID:11819 (SSTAR profile)
UniProt ID (human)	COT2_HUMAN
UniProt ID (mouse)	COT2_MOUSE
UniProt AC (human)	P24468 (TFClass)
UniProt AC (mouse)	P43135 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	11 human, 1 mouse
HT-SELEX	0
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	COT2.H13INVITRO.1.P.D.pcm
PWM	COT2.H13INVITRO.1.P.D.pwm
PFM	COT2.H13INVITRO.1.P.D.pfm
Threshold to P-value map	COT2.H13INVITRO.1.P.D.thr
Motif in other formats
JASPAR format	COT2.H13INVITRO.1.P.D_jaspar_format.txt
MEME format	COT2.H13INVITRO.1.P.D_meme_format.meme
Transfac format	COT2.H13INVITRO.1.P.D_transfac_format.txt
Homer format	COT2.H13INVITRO.1.P.D_homer_format_0.001.txt COT2.H13INVITRO.1.P.D_homer_format_0.0005.txt COT2.H13INVITRO.1.P.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	74.0	246.0	132.0	130.0
02	290.0	99.0	123.0	70.0
03	244.0	54.0	272.0	12.0
04	369.0	4.0	208.0	1.0
05	10.0	2.0	563.0	7.0
06	8.0	2.0	551.0	21.0
07	5.0	18.0	32.0	527.0
08	5.0	521.0	23.0	33.0
09	550.0	2.0	30.0	0.0
10	204.0	113.0	219.0	46.0
11	210.0	82.0	236.0	54.0
12	97.0	83.0	313.0	89.0

PFM

	A	C	G	T
01	0.127	0.423	0.227	0.223
02	0.498	0.17	0.211	0.12
03	0.419	0.093	0.467	0.021
04	0.634	0.007	0.357	0.002
05	0.017	0.003	0.967	0.012
06	0.014	0.003	0.947	0.036
07	0.009	0.031	0.055	0.905
08	0.009	0.895	0.04	0.057
09	0.945	0.003	0.052	0.0
10	0.351	0.194	0.376	0.079
11	0.361	0.141	0.405	0.093
12	0.167	0.143	0.538	0.153

PWM

	A	C	G	T
01	-0.666	0.521	-0.096	-0.111
02	0.684	-0.38	-0.166	-0.72
03	0.513	-0.973	0.621	-2.382
04	0.924	-3.27	0.354	-4.039
05	-2.541	-3.712	1.345	-2.84
06	-2.73	-3.712	1.324	-1.873
07	-3.105	-2.016	-1.477	1.279
08	-3.105	1.268	-1.789	-1.447
09	1.322	-3.712	-1.538	-4.526
10	0.335	-0.25	0.405	-1.128
11	0.364	-0.565	0.479	-0.973
12	-0.4	-0.553	0.76	-0.485

Standard thresholds

P-value	Threshold
0.001	4.64886
0.0005	5.51692
0.0001	7.453885