| Motif | CREB3L3.H13INVITRO.0.PSGIB.A |
| Gene (human) | CREB3L3 (GeneCards) |
| Gene synonyms (human) | CREBH |
| Gene (mouse) | Creb3l3 |
| Gene synonyms (mouse) | Crebh |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | CREB3L3.H13INVITRO.0.PSGIB.A |
| Gene (human) | CREB3L3 (GeneCards) |
| Gene synonyms (human) | CREBH |
| Gene (mouse) | Creb3l3 |
| Gene synonyms (mouse) | Crebh |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 14 |
| Consensus | dKvYSACGTGGCRb |
| GC content | 61.72% |
| Information content (bits; total / per base) | 16.191 / 1.156 |
| Data sources | ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM |
| Aligned words | 426 |
| Previous names |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|
| Overall | 1 (1) | 0.753 | 0.753 | 0.692 | 0.692 | 0.7 | 0.7 | 45.721 | 45.721 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| overall, 4 experiments | median | 0.965 | 0.963 | 0.871 | 0.87 | 0.75 | 0.758 |
| best | 1.0 | 1.0 | 0.993 | 0.992 | 0.866 | 0.876 | |
| Lysate, 2 experiments | median | 1.0 | 1.0 | 0.978 | 0.977 | 0.843 | 0.854 |
| best | 1.0 | 1.0 | 0.993 | 0.992 | 0.866 | 0.876 | |
| IVT, 1 experiments | median | 0.781 | 0.748 | 0.682 | 0.661 | 0.618 | 0.608 |
| best | 0.781 | 0.748 | 0.682 | 0.661 | 0.618 | 0.608 | |
| GFPIVT, 1 experiments | median | 0.929 | 0.926 | 0.779 | 0.778 | 0.679 | 0.683 |
| best | 0.929 | 0.926 | 0.779 | 0.778 | 0.679 | 0.683 | |
| Genomic HT-SELEX benchmarking | Centrality | pseudo-auROC | auROC | auPR | |
|---|---|---|---|---|---|
| overall, 3 experiments | median | 333.678 | 0.838 | 0.873 | 0.872 |
| best | 551.244 | 0.944 | 0.953 | 0.946 | |
| Lysate, 2 experiments | median | 351.852 | 0.838 | 0.889 | 0.886 |
| best | 551.244 | 0.944 | 0.953 | 0.946 | |
| GFPIVT, 1 experiments | median | 208.155 | 0.838 | 0.866 | 0.872 |
| best | 333.678 | 0.875 | 0.891 | 0.896 | |
| SMiLE-Seq benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 1 experiments | median | 0.682 | 0.655 | 0.61 | 0.596 | 0.563 | 0.561 |
| best | 0.682 | 0.655 | 0.61 | 0.596 | 0.563 | 0.561 | |
| PBM benchmarking | auROC, QNZS | auPR, QNZS | auROC, SD | auPR, SD | |
|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.931 | 0.277 | 0.894 | 0.244 |
| best | 0.947 | 0.301 | 0.895 | 0.273 | |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic leucine zipper factors (bZIP) {1.1} (TFClass) |
| TF family | CREB-related {1.1.7} (TFClass) |
| TF subfamily | CREB3-like {1.1.7.2} (TFClass) |
| TFClass ID | TFClass: 1.1.7.2.4 |
| HGNC | HGNC:18855 |
| MGI | MGI:2384786 |
| EntrezGene (human) | GeneID:84699 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:208677 (SSTAR profile) |
| UniProt ID (human) | CR3L3_HUMAN |
| UniProt ID (mouse) | CR3L3_MOUSE |
| UniProt AC (human) | Q68CJ9 (TFClass) |
| UniProt AC (mouse) | Q91XE9 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 1 human, 0 mouse |
| HT-SELEX | 4 overall: 2 Lysate, 1 IVT, 1 GFPIVT |
| Genomic HT-SELEX | 3 overall: 2 Lysate, 0 IVT, 1 GFPIVT |
| SMiLE-Seq | 1 |
| PBM | 4 |
| PCM | CREB3L3.H13INVITRO.0.PSGIB.A.pcm |
| PWM | CREB3L3.H13INVITRO.0.PSGIB.A.pwm |
| PFM | CREB3L3.H13INVITRO.0.PSGIB.A.pfm |
| Threshold to P-value map | CREB3L3.H13INVITRO.0.PSGIB.A.thr |
| Motif in other formats | |
| JASPAR format | CREB3L3.H13INVITRO.0.PSGIB.A_jaspar_format.txt |
| MEME format | CREB3L3.H13INVITRO.0.PSGIB.A_meme_format.meme |
| Transfac format | CREB3L3.H13INVITRO.0.PSGIB.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 68.0 | 54.0 | 86.0 | 218.0 |
| 02 | 17.0 | 13.0 | 277.0 | 119.0 |
| 03 | 98.0 | 51.0 | 241.0 | 36.0 |
| 04 | 47.0 | 132.0 | 5.0 | 242.0 |
| 05 | 8.0 | 168.0 | 246.0 | 4.0 |
| 06 | 424.0 | 0.0 | 2.0 | 0.0 |
| 07 | 0.0 | 424.0 | 0.0 | 2.0 |
| 08 | 3.0 | 0.0 | 423.0 | 0.0 |
| 09 | 0.0 | 0.0 | 0.0 | 426.0 |
| 10 | 0.0 | 8.0 | 418.0 | 0.0 |
| 11 | 10.0 | 0.0 | 392.0 | 24.0 |
| 12 | 81.0 | 339.0 | 2.0 | 4.0 |
| 13 | 316.0 | 33.0 | 55.0 | 22.0 |
| 14 | 54.0 | 130.0 | 182.0 | 60.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.16 | 0.127 | 0.202 | 0.512 |
| 02 | 0.04 | 0.031 | 0.65 | 0.279 |
| 03 | 0.23 | 0.12 | 0.566 | 0.085 |
| 04 | 0.11 | 0.31 | 0.012 | 0.568 |
| 05 | 0.019 | 0.394 | 0.577 | 0.009 |
| 06 | 0.995 | 0.0 | 0.005 | 0.0 |
| 07 | 0.0 | 0.995 | 0.0 | 0.005 |
| 08 | 0.007 | 0.0 | 0.993 | 0.0 |
| 09 | 0.0 | 0.0 | 0.0 | 1.0 |
| 10 | 0.0 | 0.019 | 0.981 | 0.0 |
| 11 | 0.023 | 0.0 | 0.92 | 0.056 |
| 12 | 0.19 | 0.796 | 0.005 | 0.009 |
| 13 | 0.742 | 0.077 | 0.129 | 0.052 |
| 14 | 0.127 | 0.305 | 0.427 | 0.141 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.441 | -0.666 | -0.21 | 0.709 |
| 02 | -1.764 | -2.007 | 0.947 | 0.11 |
| 03 | -0.082 | -0.721 | 0.809 | -1.058 |
| 04 | -0.8 | 0.212 | -2.808 | 0.813 |
| 05 | -2.43 | 0.451 | 0.829 | -2.975 |
| 06 | 1.371 | -4.268 | -3.426 | -4.268 |
| 07 | -4.268 | 1.371 | -4.268 | -3.426 |
| 08 | -3.175 | -4.268 | 1.369 | -4.268 |
| 09 | -4.268 | -4.268 | -4.268 | 1.376 |
| 10 | -4.268 | -2.43 | 1.357 | -4.268 |
| 11 | -2.239 | -4.268 | 1.293 | -1.443 |
| 12 | -0.269 | 1.148 | -3.426 | -2.975 |
| 13 | 1.078 | -1.141 | -0.648 | -1.525 |
| 14 | -0.666 | 0.197 | 0.53 | -0.563 |
| P-value | Threshold |
|---|---|
| 0.001 | 2.04416 |
| 0.0005 | 3.40221 |
| 0.0001 | 6.197165 |