MotifCREB3L3.H13INVIVO.0.PSGIB.A
Gene (human)CREB3L3
(GeneCards)
Gene synonyms (human)CREBH
Gene (mouse)Creb3l3
Gene synonyms (mouse)Crebh
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length14
ConsensusbKvYSACGTGGCRb
GC content62.98%
Information content (bits; total / per base)15.353 / 1.097
Data sourcesChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM
Aligned words426
Previous names

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best Centrality, median Centrality, best
Overall 1 (1) 0.775 0.775 0.696 0.696 0.698 0.698 50.237 50.237

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
overall, 4 experiments median 0.963 0.961 0.871 0.869 0.751 0.758
best 1.0 0.999 0.992 0.991 0.867 0.877
Lysate, 2 experiments median 1.0 0.999 0.976 0.976 0.844 0.854
best 1.0 0.999 0.992 0.991 0.867 0.877
IVT, 1 experiments median 0.773 0.741 0.676 0.656 0.612 0.604
best 0.773 0.741 0.676 0.656 0.612 0.604
GFPIVT, 1 experiments median 0.926 0.923 0.78 0.778 0.68 0.684
best 0.926 0.923 0.78 0.778 0.68 0.684

Genomic HT-SELEX benchmarking Centrality pseudo-auROC auROC auPR
overall, 3 experiments median 338.921 0.847 0.896 0.881
best 548.26 0.948 0.958 0.947
Lysate, 2 experiments median 352.472 0.85 0.91 0.894
best 548.26 0.948 0.958 0.947
GFPIVT, 1 experiments median 205.62 0.847 0.895 0.881
best 340.42 0.882 0.918 0.906

SMiLE-Seq benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 1 experiments median 0.669 0.645 0.599 0.588 0.557 0.556
best 0.669 0.645 0.599 0.588 0.557 0.556

PBM benchmarking auROC, QNZS auPR, QNZS auROC, SD auPR, SD
Overall, 4 experiments median 0.921 0.242 0.882 0.215
best 0.938 0.26 0.882 0.238
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyCREB-related {1.1.7} (TFClass)
TF subfamilyCREB3-like {1.1.7.2} (TFClass)
TFClass IDTFClass: 1.1.7.2.4
HGNCHGNC:18855
MGIMGI:2384786
EntrezGene (human)GeneID:84699
(SSTAR profile)
EntrezGene (mouse)GeneID:208677
(SSTAR profile)
UniProt ID (human)CR3L3_HUMAN
UniProt ID (mouse)CR3L3_MOUSE
UniProt AC (human)Q68CJ9
(TFClass)
UniProt AC (mouse)Q91XE9
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 4 overall: 2 Lysate, 1 IVT, 1 GFPIVT
Genomic HT-SELEX 3 overall: 2 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq 1
PBM 4
PCM
ACGT
0145.062.0119.0200.0
0214.022.0280.0110.0
0392.045.0247.042.0
0439.0134.010.0243.0
0510.0165.0250.01.0
06424.00.01.01.0
070.0419.00.07.0
084.00.0421.01.0
091.01.03.0421.0
100.015.0407.04.0
1118.00.0383.025.0
1280.0335.06.05.0
13267.047.070.042.0
1443.0105.0209.069.0
PFM
ACGT
010.1060.1460.2790.469
020.0330.0520.6570.258
030.2160.1060.580.099
040.0920.3150.0230.57
050.0230.3870.5870.002
060.9950.00.0020.002
070.00.9840.00.016
080.0090.00.9880.002
090.0020.0020.0070.988
100.00.0350.9550.009
110.0420.00.8990.059
120.1880.7860.0140.012
130.6270.110.1640.099
140.1010.2460.4910.162
PWM
ACGT
01-0.843-0.5310.110.624
02-1.941-1.5250.9580.032
03-0.144-0.8430.833-0.909
04-0.9810.227-2.2390.817
05-2.2390.4330.845-3.761
061.371-4.268-3.761-3.761
07-4.2681.359-4.268-2.541
08-2.975-4.2681.364-3.761
09-3.761-3.761-3.1751.364
10-4.268-1.8781.33-2.975
11-1.711-4.2681.27-1.405
12-0.2811.136-2.666-2.808
130.911-0.8-0.412-0.909
14-0.886-0.0140.667-0.426
Standard thresholds
P-value Threshold
0.001 2.68061
0.0005 3.93326
0.0001 6.52666