| Motif | DMBX1.H13INVIVO.0.SM.D |
| Gene (human) | DMBX1 (GeneCards) |
| Gene synonyms (human) | MBX, OTX3, PAXB |
| Gene (mouse) | Dmbx1 |
| Gene synonyms (mouse) | Cdmx, Mbx, Otx3, PaxB |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | D |
| Motif | DMBX1.H13INVIVO.0.SM.D |
| Gene (human) | DMBX1 (GeneCards) |
| Gene synonyms (human) | MBX, OTX3, PAXB |
| Gene (mouse) | Dmbx1 |
| Gene synonyms (mouse) | Cdmx, Mbx, Otx3, PaxB |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | D |
| Motif length | 9 |
| Consensus | nbSATTAvn |
| GC content | 40.65% |
| Information content (bits; total / per base) | 7.59 / 0.843 |
| Data sources | HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 8418 |
| Previous names | DMBX1.H12INVIVO.0.SM.D |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.907 | 0.857 | 0.864 | 0.812 | 0.787 | 0.749 |
| best | 0.984 | 0.973 | 0.973 | 0.958 | 0.934 | 0.915 | |
| Methyl HT-SELEX, 2 experiments | median | 0.95 | 0.923 | 0.92 | 0.889 | 0.858 | 0.832 |
| best | 0.984 | 0.973 | 0.973 | 0.958 | 0.934 | 0.915 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.811 | 0.765 | 0.742 | 0.708 | 0.676 | 0.657 |
| best | 0.937 | 0.897 | 0.908 | 0.864 | 0.845 | 0.806 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.58 | 0.128 | 0.488 | 0.297 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | Paired-related HD {3.1.3} (TFClass) |
| TF subfamily | DMBX {3.1.3.4} (TFClass) |
| TFClass ID | TFClass: 3.1.3.4.1 |
| HGNC | HGNC:19026 |
| MGI | MGI:2153518 |
| EntrezGene (human) | GeneID:127343 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:140477 (SSTAR profile) |
| UniProt ID (human) | DMBX1_HUMAN |
| UniProt ID (mouse) | DMBX1_MOUSE |
| UniProt AC (human) | Q8NFW5 (TFClass) |
| UniProt AC (mouse) | Q91ZK4 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 0 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 2 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | DMBX1.H13INVIVO.0.SM.D.pcm |
| PWM | DMBX1.H13INVIVO.0.SM.D.pwm |
| PFM | DMBX1.H13INVIVO.0.SM.D.pfm |
| Threshold to P-value map | DMBX1.H13INVIVO.0.SM.D.thr |
| Motif in other formats | |
| JASPAR format | DMBX1.H13INVIVO.0.SM.D_jaspar_format.txt |
| MEME format | DMBX1.H13INVIVO.0.SM.D_meme_format.meme |
| Transfac format | DMBX1.H13INVIVO.0.SM.D_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1943.25 | 2495.25 | 2418.25 | 1561.25 |
| 02 | 1216.75 | 1970.75 | 3784.75 | 1445.75 |
| 03 | 328.0 | 1461.0 | 6474.0 | 155.0 |
| 04 | 6721.0 | 1428.0 | 268.0 | 1.0 |
| 05 | 0.0 | 1.0 | 0.0 | 8417.0 |
| 06 | 10.0 | 463.0 | 0.0 | 7945.0 |
| 07 | 7633.0 | 511.0 | 60.0 | 214.0 |
| 08 | 3188.5 | 1677.5 | 2503.5 | 1048.5 |
| 09 | 1341.25 | 2872.25 | 2407.25 | 1797.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.231 | 0.296 | 0.287 | 0.185 |
| 02 | 0.145 | 0.234 | 0.45 | 0.172 |
| 03 | 0.039 | 0.174 | 0.769 | 0.018 |
| 04 | 0.798 | 0.17 | 0.032 | 0.0 |
| 05 | 0.0 | 0.0 | 0.0 | 1.0 |
| 06 | 0.001 | 0.055 | 0.0 | 0.944 |
| 07 | 0.907 | 0.061 | 0.007 | 0.025 |
| 08 | 0.379 | 0.199 | 0.297 | 0.125 |
| 09 | 0.159 | 0.341 | 0.286 | 0.214 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.08 | 0.17 | 0.139 | -0.298 |
| 02 | -0.547 | -0.066 | 0.586 | -0.375 |
| 03 | -1.853 | -0.364 | 1.123 | -2.595 |
| 04 | 1.16 | -0.387 | -2.054 | -6.471 |
| 05 | -6.838 | -6.471 | -6.838 | 1.385 |
| 06 | -5.147 | -1.51 | -6.838 | 1.328 |
| 07 | 1.288 | -1.412 | -3.522 | -2.276 |
| 08 | 0.415 | -0.227 | 0.173 | -0.696 |
| 09 | -0.45 | 0.311 | 0.134 | -0.158 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.41093 |
| 0.0005 | 6.05508 |
| 0.0001 | 6.94548 |