ELF4.H13INVITRO.1.M.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ELF4.H13INVITRO.1.M.B
Gene (human)	ELF4 (GeneCards)
Gene synonyms (human)	ELFR, MEF
Gene (mouse)	Elf4
Gene synonyms (mouse)	Mef
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	15
Consensus	nvdWvSAGGAAGTRn
GC content	48.62%
Information content (bits; total / per base)	14.946 / 0.996
Data sources	Methyl-HT-SELEX
Aligned words	9772
Previous names	ELF4.H12INVITRO.1.M.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	3 (21)	0.749	0.85	0.631	0.763	0.769	0.869	2.671	3.437	61.495	129.921
Mouse	3 (19)	0.932	0.941	0.86	0.875	0.942	0.948	3.984	4.317	172.678	237.824

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.997	0.995	0.995	0.992	0.988	0.983
Overall, 4 experiments	best	0.999	0.999	0.998	0.997	0.992	0.99
Methyl HT-SELEX, 2 experiments	median	0.998	0.997	0.997	0.995	0.988	0.984
Methyl HT-SELEX, 2 experiments	best	0.999	0.999	0.998	0.997	0.992	0.99
Non-Methyl HT-SELEX, 2 experiments	median	0.994	0.99	0.992	0.987	0.984	0.977
Non-Methyl HT-SELEX, 2 experiments	best	0.997	0.994	0.996	0.992	0.992	0.988

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.921	0.702	0.894	0.675

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ELF1-like {3.5.2.3} (TFClass)
TFClass ID	TFClass: 3.5.2.3.3
HGNC	HGNC:3319
MGI	MGI:1928377
EntrezGene (human)	GeneID:2000 (SSTAR profile)
EntrezGene (mouse)	GeneID:56501 (SSTAR profile)
UniProt ID (human)	ELF4_HUMAN
UniProt ID (mouse)	ELF4_MOUSE
UniProt AC (human)	Q99607 (TFClass)
UniProt AC (mouse)	Q9Z2U4 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	3 human, 3 mouse
HT-SELEX	2
Methyl-HT-SELEX	2
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ELF4.H13INVITRO.1.M.B.pcm
PWM	ELF4.H13INVITRO.1.M.B.pwm
PFM	ELF4.H13INVITRO.1.M.B.pfm
Threshold to P-value map	ELF4.H13INVITRO.1.M.B.thr
Motif in other formats
JASPAR format	ELF4.H13INVITRO.1.M.B_jaspar_format.txt
MEME format	ELF4.H13INVITRO.1.M.B_meme_format.meme
Transfac format	ELF4.H13INVITRO.1.M.B_transfac_format.txt
Homer format	ELF4.H13INVITRO.1.M.B_homer_format_0.001.txt ELF4.H13INVITRO.1.M.B_homer_format_0.0005.txt ELF4.H13INVITRO.1.M.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2544.75	2241.75	3218.75	1766.75
02	1958.0	1802.0	4460.0	1552.0
03	4634.0	987.0	2504.0	1647.0
04	6566.0	409.0	805.0	1992.0
05	3746.0	2758.0	1797.0	1471.0
06	482.0	7860.0	975.0	455.0
07	8014.0	1716.0	34.0	8.0
08	0.0	1.0	9769.0	2.0
09	0.0	0.0	9772.0	0.0
10	9772.0	0.0	0.0	0.0
11	9760.0	1.0	0.0	11.0
12	478.0	37.0	9255.0	2.0
13	110.0	667.0	255.0	8740.0
14	4417.0	594.0	4063.0	698.0
15	2838.0	2758.0	2526.0	1650.0

PFM

	A	C	G	T
01	0.26	0.229	0.329	0.181
02	0.2	0.184	0.456	0.159
03	0.474	0.101	0.256	0.169
04	0.672	0.042	0.082	0.204
05	0.383	0.282	0.184	0.151
06	0.049	0.804	0.1	0.047
07	0.82	0.176	0.003	0.001
08	0.0	0.0	1.0	0.0
09	0.0	0.0	1.0	0.0
10	1.0	0.0	0.0	0.0
11	0.999	0.0	0.0	0.001
12	0.049	0.004	0.947	0.0
13	0.011	0.068	0.026	0.894
14	0.452	0.061	0.416	0.071
15	0.29	0.282	0.258	0.169

PWM

	A	C	G	T
01	0.041	-0.086	0.276	-0.324
02	-0.221	-0.304	0.601	-0.453
03	0.64	-0.905	0.025	-0.394
04	0.988	-1.783	-1.108	-0.204
05	0.427	0.121	-0.307	-0.507
06	-1.619	1.168	-0.917	-1.677
07	1.187	-0.353	-4.21	-5.47
08	-6.97	-6.609	1.385	-6.344
09	-6.97	-6.97	1.386	-6.97
10	1.386	-6.97	-6.97	-6.97
11	1.384	-6.609	-6.97	-5.214
12	-1.628	-4.131	1.331	-6.344
13	-3.081	-1.296	-2.252	1.274
14	0.592	-1.411	0.508	-1.25
15	0.15	0.121	0.033	-0.392

Standard thresholds

P-value	Threshold
0.001	1.24596
0.0005	3.01946
0.0001	6.49456