ETS2.H13RSNP.0.S.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ETS2.H13RSNP.0.S.C
Gene (human)	ETS2 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Ets2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	19
Consensus	nWCCGGAAGYRYWTCCKbn
GC content	58.86%
Information content (bits; total / per base)	21.795 / 1.147
Data sources	HT-SELEX
Aligned words	5700
Previous names	ETS2.H12RSNP.0.S.C

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (11)	0.561	0.573	0.397	0.411	0.475	0.505	0.969	1.125	0	2.699
Mouse	2 (13)	0.735	0.783	0.604	0.64	0.653	0.674	1.831	1.917	25.056	40.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.995	0.995	0.92	0.915	0.757	0.777
Non-Methyl HT-SELEX, 1 experiments	best	0.995	0.995	0.92	0.915	0.757	0.777

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.734	0.532	0.605	0.377

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Tryptophan cluster factors {3.5} (TFClass)
TF family	Ets-related {3.5.2} (TFClass)
TF subfamily	ETS-like {3.5.2.1} (TFClass)
TFClass ID	TFClass: 3.5.2.1.2
HGNC	HGNC:3489
MGI	MGI:95456
EntrezGene (human)	GeneID:2114 (SSTAR profile)
EntrezGene (mouse)	GeneID:23872 (SSTAR profile)
UniProt ID (human)	ETS2_HUMAN
UniProt ID (mouse)	ETS2_MOUSE
UniProt AC (human)	P15036 (TFClass)
UniProt AC (mouse)	P15037 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 2 mouse
HT-SELEX	1
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ETS2.H13RSNP.0.S.C.pcm
PWM	ETS2.H13RSNP.0.S.C.pwm
PFM	ETS2.H13RSNP.0.S.C.pfm
Threshold to P-value map	ETS2.H13RSNP.0.S.C.thr
Motif in other formats
JASPAR format	ETS2.H13RSNP.0.S.C_jaspar_format.txt
MEME format	ETS2.H13RSNP.0.S.C_meme_format.meme
Transfac format	ETS2.H13RSNP.0.S.C_transfac_format.txt
Homer format	ETS2.H13RSNP.0.S.C_homer_format_0.001.txt ETS2.H13RSNP.0.S.C_homer_format_0.0005.txt ETS2.H13RSNP.0.S.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1473.75	1403.75	1369.75	1452.75
02	3765.5	263.5	808.5	862.5
03	127.0	5198.0	372.0	3.0
04	200.0	5499.0	1.0	0.0
05	0.0	0.0	5700.0	0.0
06	0.0	0.0	5700.0	0.0
07	5700.0	0.0	0.0	0.0
08	4473.0	8.0	1.0	1218.0
09	1263.0	6.0	4430.0	1.0
10	39.0	2081.0	120.0	3460.0
11	2646.0	430.0	2478.0	146.0
12	105.0	4435.0	258.0	902.0
13	1898.0	78.0	236.0	3488.0
14	145.0	98.0	78.0	5379.0
15	90.0	5467.0	88.0	55.0
16	64.0	5497.0	64.0	75.0
17	121.0	232.0	4193.0	1154.0
18	438.75	1364.75	3104.75	791.75
19	1137.0	1689.0	990.0	1884.0

PFM

	A	C	G	T
01	0.259	0.246	0.24	0.255
02	0.661	0.046	0.142	0.151
03	0.022	0.912	0.065	0.001
04	0.035	0.965	0.0	0.0
05	0.0	0.0	1.0	0.0
06	0.0	0.0	1.0	0.0
07	1.0	0.0	0.0	0.0
08	0.785	0.001	0.0	0.214
09	0.222	0.001	0.777	0.0
10	0.007	0.365	0.021	0.607
11	0.464	0.075	0.435	0.026
12	0.018	0.778	0.045	0.158
13	0.333	0.014	0.041	0.612
14	0.025	0.017	0.014	0.944
15	0.016	0.959	0.015	0.01
16	0.011	0.964	0.011	0.013
17	0.021	0.041	0.736	0.202
18	0.077	0.239	0.545	0.139
19	0.199	0.296	0.174	0.331

PWM

	A	C	G	T
01	0.034	-0.015	-0.039	0.019
02	0.971	-1.681	-0.566	-0.501
03	-2.402	1.293	-1.339	-5.622
04	-1.954	1.349	-6.112	-6.492
05	-6.492	-6.492	1.385	-6.492
06	-6.492	-6.492	1.385	-6.492
07	1.385	-6.492	-6.492	-6.492
08	1.143	-4.945	-6.112	-0.157
09	-0.12	-5.164	1.133	-6.112
10	-3.546	0.378	-2.458	0.886
11	0.618	-1.195	0.553	-2.265
12	-2.589	1.134	-1.702	-0.456
13	0.286	-2.879	-1.79	0.894
14	-2.272	-2.657	-2.879	1.327
15	-2.74	1.343	-2.762	-3.218
16	-3.071	1.349	-3.071	-2.918
17	-2.45	-1.807	1.078	-0.211
18	-1.175	-0.043	0.778	-0.586
19	-0.225	0.17	-0.364	0.279

Standard thresholds

P-value	Threshold
0.001	-3.33829
0.0005	-1.41949
0.0001	2.58496