FAM200B.H13INVIVO.0.PSGIB.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FAM200B.H13INVIVO.0.PSGIB.A
Gene (human)	FAM200B (GeneCards)
Gene synonyms (human)
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	15
Consensus	hGGGYCSCRSSSbSS
GC content	84.75%
Information content (bits; total / per base)	13.975 / 0.932
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM
Aligned words	997
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.865	0.873	0.712	0.729	0.726	0.728	92.675	111.013

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 3 experiments	median	0.805	0.807	0.632	0.661	0.557	0.589
overall, 3 experiments	best	0.995	0.99	0.993	0.988	0.951	0.951
IVT, 1 experiments	median	0.805	0.807	0.632	0.661	0.557	0.589
IVT, 1 experiments	best	0.805	0.807	0.632	0.661	0.557	0.589
GFPIVT, 2 experiments	median	0.781	0.791	0.752	0.762	0.725	0.734
GFPIVT, 2 experiments	best	0.995	0.99	0.993	0.988	0.951	0.951

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 1 experiments	median	79.565	0.769	0.847	0.704
GFPIVT, 1 experiments	best	320.398	0.775	0.858	0.706

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.97	0.959	0.863	0.861	0.705	0.733
Overall, 2 experiments	best	0.987	0.983	0.942	0.931	0.783	0.799

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 4 experiments	median	0.87	0.05	0.877	0.137
Overall, 4 experiments	best	0.89	0.051	0.879	0.163

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	BED zinc finger {2.3.5} (TFClass)
TF subfamily	{2.3.5.0} (TFClass)
TFClass ID	TFClass: 2.3.5.0.255
HGNC
MGI
EntrezGene (human)
EntrezGene (mouse)
UniProt ID (human)	F200B_HUMAN
UniProt ID (mouse)
UniProt AC (human)	P0CF97 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	no

ChIP-Seq	2 human, 0 mouse
HT-SELEX	3 overall: 0 Lysate, 1 IVT, 2 GFPIVT
Genomic HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	2
PBM	4

PCM	FAM200B.H13INVIVO.0.PSGIB.A.pcm
PWM	FAM200B.H13INVIVO.0.PSGIB.A.pwm
PFM	FAM200B.H13INVIVO.0.PSGIB.A.pfm
Threshold to P-value map	FAM200B.H13INVIVO.0.PSGIB.A.thr
Motif in other formats
JASPAR format	FAM200B.H13INVIVO.0.PSGIB.A_jaspar_format.txt
MEME format	FAM200B.H13INVIVO.0.PSGIB.A_meme_format.meme
Transfac format	FAM200B.H13INVIVO.0.PSGIB.A_transfac_format.txt
Homer format	FAM200B.H13INVIVO.0.PSGIB.A_homer_format_0.001.txt FAM200B.H13INVIVO.0.PSGIB.A_homer_format_0.0005.txt FAM200B.H13INVIVO.0.PSGIB.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	237.0	360.0	79.0	321.0
02	14.0	3.0	973.0	7.0
03	3.0	1.0	992.0	1.0
04	0.0	0.0	985.0	12.0
05	1.0	295.0	173.0	528.0
06	2.0	988.0	2.0	5.0
07	40.0	344.0	587.0	26.0
08	20.0	795.0	59.0	123.0
09	136.0	123.0	726.0	12.0
10	91.0	161.0	724.0	21.0
11	107.0	412.0	454.0	24.0
12	52.0	430.0	456.0	59.0
13	64.0	504.0	331.0	98.0
14	72.0	591.0	275.0	59.0
15	68.0	557.0	295.0	77.0

PFM

	A	C	G	T
01	0.238	0.361	0.079	0.322
02	0.014	0.003	0.976	0.007
03	0.003	0.001	0.995	0.001
04	0.0	0.0	0.988	0.012
05	0.001	0.296	0.174	0.53
06	0.002	0.991	0.002	0.005
07	0.04	0.345	0.589	0.026
08	0.02	0.797	0.059	0.123
09	0.136	0.123	0.728	0.012
10	0.091	0.161	0.726	0.021
11	0.107	0.413	0.455	0.024
12	0.052	0.431	0.457	0.059
13	0.064	0.506	0.332	0.098
14	0.072	0.593	0.276	0.059
15	0.068	0.559	0.296	0.077

PWM

	A	C	G	T
01	-0.05	0.366	-1.134	0.251
02	-2.77	-3.972	1.357	-3.359
03	-3.972	-4.522	1.376	-4.522
04	-4.979	-4.979	1.369	-2.906
05	-4.522	0.167	-0.362	0.747
06	-4.21	1.372	-4.21	-3.619
07	-1.794	0.32	0.853	-2.203
08	-2.447	1.155	-1.419	-0.699
09	-0.6	-0.699	1.065	-2.906
10	-0.996	-0.433	1.062	-2.402
11	-0.837	0.5	0.597	-2.278
12	-1.541	0.542	0.601	-1.419
13	-1.34	0.701	0.282	-0.923
14	-1.225	0.859	0.098	-1.419
15	-1.281	0.8	0.167	-1.159

Standard thresholds

P-value	Threshold
0.001	3.23481
0.0005	4.43956
0.0001	6.90141