FBXL19.H13RSNP.0.PSGIB.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FBXL19.H13RSNP.0.PSGIB.D
Gene (human)	FBXL19 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Fbxl19
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	7
Consensus	nbTACGn
GC content	50.44%
Information content (bits; total / per base)	8.169 / 1.167
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM
Aligned words	635
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.487	0.489	0.321	0.325	0.426	0.426	0.0	0.0

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 3 experiments	median	0.861	0.818	0.772	0.735	0.697	0.671
overall, 3 experiments	best	0.913	0.877	0.851	0.81	0.78	0.743
Lysate, 1 experiments	median	0.913	0.877	0.851	0.81	0.78	0.743
Lysate, 1 experiments	best	0.913	0.877	0.851	0.81	0.78	0.743
IVT, 1 experiments	median	0.861	0.818	0.772	0.735	0.697	0.671
IVT, 1 experiments	best	0.861	0.818	0.772	0.735	0.697	0.671
GFPIVT, 1 experiments	median	0.718	0.664	0.654	0.617	0.617	0.588
GFPIVT, 1 experiments	best	0.718	0.664	0.654	0.617	0.617	0.588

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
Lysate, 1 experiments	median	8.144	0.423	0.605	0.473
Lysate, 1 experiments	best	23.208	0.424	0.613	0.491

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.891	0.845	0.833	0.784	0.766	0.724
Overall, 2 experiments	best	0.899	0.856	0.839	0.793	0.769	0.73

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 3 experiments	median	0.888	0.028	0.88	0.158
Overall, 3 experiments	best	0.888	0.028	0.9	0.162

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	CXXC zinc finger factors {2.6} (TFClass)
TF family	CpG-binding {2.6.1} (TFClass)
TF subfamily	{2.6.1.0} (TFClass)
TFClass ID	TFClass: 2.6.1.0.256
HGNC
MGI
EntrezGene (human)
EntrezGene (mouse)
UniProt ID (human)	FXL19_HUMAN
UniProt ID (mouse)	FXL19_MOUSE
UniProt AC (human)	Q6PCT2 (TFClass)
UniProt AC (mouse)	Q6PB97 (TFClass)
GRECO-DB-TF	no

ChIP-Seq	2 human, 0 mouse
HT-SELEX	3 overall: 1 Lysate, 1 IVT, 1 GFPIVT
Genomic HT-SELEX	1 overall: 1 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	2
PBM	3

PCM	FBXL19.H13RSNP.0.PSGIB.D.pcm
PWM	FBXL19.H13RSNP.0.PSGIB.D.pwm
PFM	FBXL19.H13RSNP.0.PSGIB.D.pfm
Threshold to P-value map	FBXL19.H13RSNP.0.PSGIB.D.thr
Motif in other formats
JASPAR format	FBXL19.H13RSNP.0.PSGIB.D_jaspar_format.txt
MEME format	FBXL19.H13RSNP.0.PSGIB.D_meme_format.meme
Transfac format	FBXL19.H13RSNP.0.PSGIB.D_transfac_format.txt
Homer format	FBXL19.H13RSNP.0.PSGIB.D_homer_format_0.001.txt FBXL19.H13RSNP.0.PSGIB.D_homer_format_0.0005.txt FBXL19.H13RSNP.0.PSGIB.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	134.0	168.0	222.0	111.0
02	95.0	148.0	126.0	266.0
03	0.0	0.0	0.0	635.0
04	635.0	0.0	0.0	0.0
05	0.0	635.0	0.0	0.0
06	0.0	0.0	635.0	0.0
07	152.0	174.0	134.0	175.0

PFM

	A	C	G	T
01	0.211	0.265	0.35	0.175
02	0.15	0.233	0.198	0.419
03	0.0	0.0	0.0	1.0
04	1.0	0.0	0.0	0.0
05	0.0	1.0	0.0	0.0
06	0.0	0.0	1.0	0.0
07	0.239	0.274	0.211	0.276

PWM

	A	C	G	T
01	-0.168	0.056	0.332	-0.353
02	-0.507	-0.069	-0.228	0.512
03	-4.599	-4.599	-4.599	1.379
04	1.379	-4.599	-4.599	-4.599
05	-4.599	1.379	-4.599	-4.599
06	-4.599	-4.599	1.379	-4.599
07	-0.043	0.091	-0.168	0.097

Standard thresholds

P-value	Threshold
0.001	5.71431
0.0005	5.935325
0.0001	6.39083