FLYWCH1.H13INVITRO.0.PSGB.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FLYWCH1.H13INVITRO.0.PSGB.A
Gene (human)	FLYWCH1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Flywch1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	26
Consensus	nvnWTTCGAhYYKAWTCGRhbbddhn
GC content	48.81%
Information content (bits; total / per base)	18.962 / 0.729
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + PBM
Aligned words	1517
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (4)	0.71	0.738	0.471	0.513	0.575	0.672	19.092	31.699

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 1 experiments	median	1.0	1.0	0.999	0.999	0.977	0.976
GFPIVT, 1 experiments	best	1.0	1.0	0.999	0.999	0.977	0.976

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 3 experiments	median	22.796	0.931	0.699	0.568
overall, 3 experiments	best	66.387	0.951	0.779	0.68
Lysate, 2 experiments	median	43.748	0.941	0.734	0.587
Lysate, 2 experiments	best	66.387	0.951	0.779	0.641
GFPIVT, 1 experiments	median	22.796	0.927	0.699	0.568
GFPIVT, 1 experiments	best	37.046	0.945	0.767	0.68

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 2 experiments	median	0.712	0.007	0.663	0.005
Overall, 2 experiments	best	0.712	0.007	0.663	0.005

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	FLYWCH {2.3.4.255} (TFClass)
TFClass ID	TFClass: 2.3.4.255.1
HGNC
MGI
EntrezGene (human)
EntrezGene (mouse)
UniProt ID (human)	FWCH1_HUMAN
UniProt ID (mouse)	FWCH1_MOUSE
UniProt AC (human)	Q4VC44 (TFClass)
UniProt AC (mouse)	Q8CI03 (TFClass)
GRECO-DB-TF	no

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	3 overall: 2 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	0
PBM	2

PCM	FLYWCH1.H13INVITRO.0.PSGB.A.pcm
PWM	FLYWCH1.H13INVITRO.0.PSGB.A.pwm
PFM	FLYWCH1.H13INVITRO.0.PSGB.A.pfm
Threshold to P-value map	FLYWCH1.H13INVITRO.0.PSGB.A.thr
Motif in other formats
JASPAR format	FLYWCH1.H13INVITRO.0.PSGB.A_jaspar_format.txt
MEME format	FLYWCH1.H13INVITRO.0.PSGB.A_meme_format.meme
Transfac format	FLYWCH1.H13INVITRO.0.PSGB.A_transfac_format.txt
Homer format	FLYWCH1.H13INVITRO.0.PSGB.A_homer_format_0.001.txt FLYWCH1.H13INVITRO.0.PSGB.A_homer_format_0.0005.txt FLYWCH1.H13INVITRO.0.PSGB.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	315.75	558.75	310.75	331.75
02	381.0	624.0	379.0	133.0
03	500.0	356.0	455.0	206.0
04	854.0	56.0	135.0	472.0
05	121.0	2.0	141.0	1253.0
06	0.0	0.0	1.0	1516.0
07	0.0	1517.0	0.0	0.0
08	0.0	0.0	1516.0	1.0
09	1088.0	29.0	398.0	2.0
10	449.0	573.0	108.0	387.0
11	77.0	697.0	82.0	661.0
12	72.0	1186.0	73.0	186.0
13	147.0	48.0	1080.0	242.0
14	1200.0	7.0	36.0	274.0
15	522.0	4.0	15.0	976.0
16	31.0	100.0	11.0	1375.0
17	16.0	1290.0	121.0	90.0
18	76.0	101.0	1310.0	30.0
19	925.0	96.0	458.0	38.0
20	312.0	647.0	147.0	411.0
21	211.0	654.0	271.0	381.0
22	155.0	676.0	399.0	287.0
23	351.0	169.0	614.0	383.0
24	572.0	167.0	250.0	528.0
25	362.0	286.0	200.0	669.0
26	238.5	572.5	324.5	381.5

PFM

	A	C	G	T
01	0.208	0.368	0.205	0.219
02	0.251	0.411	0.25	0.088
03	0.33	0.235	0.3	0.136
04	0.563	0.037	0.089	0.311
05	0.08	0.001	0.093	0.826
06	0.0	0.0	0.001	0.999
07	0.0	1.0	0.0	0.0
08	0.0	0.0	0.999	0.001
09	0.717	0.019	0.262	0.001
10	0.296	0.378	0.071	0.255
11	0.051	0.459	0.054	0.436
12	0.047	0.782	0.048	0.123
13	0.097	0.032	0.712	0.16
14	0.791	0.005	0.024	0.181
15	0.344	0.003	0.01	0.643
16	0.02	0.066	0.007	0.906
17	0.011	0.85	0.08	0.059
18	0.05	0.067	0.864	0.02
19	0.61	0.063	0.302	0.025
20	0.206	0.426	0.097	0.271
21	0.139	0.431	0.179	0.251
22	0.102	0.446	0.263	0.189
23	0.231	0.111	0.405	0.252
24	0.377	0.11	0.165	0.348
25	0.239	0.189	0.132	0.441
26	0.157	0.377	0.214	0.251

PWM

	A	C	G	T
01	-0.182	0.386	-0.198	-0.133
02	0.005	0.496	-0.001	-1.039
03	0.275	-0.063	0.181	-0.606
04	0.809	-1.885	-1.024	0.218
05	-1.132	-4.6	-0.981	1.192
06	-5.338	-5.338	-4.902	1.382
07	-5.338	1.383	-5.338	-5.338
08	-5.338	-5.338	1.382	-4.902
09	1.051	-2.514	0.048	-4.6
10	0.168	0.411	-1.244	0.02
11	-1.576	0.606	-1.514	0.554
12	-1.641	1.137	-1.628	-0.707
13	-0.94	-2.034	1.043	-0.447
14	1.149	-3.765	-2.31	-0.323
15	0.318	-4.18	-3.12	0.942
16	-2.452	-1.32	-3.391	1.285
17	-3.062	1.221	-1.132	-1.423
18	-1.588	-1.31	1.236	-2.483
19	0.889	-1.36	0.188	-2.258
20	-0.194	0.532	-0.94	0.08
21	-0.583	0.543	-0.334	0.005
22	-0.888	0.576	0.051	-0.277
23	-0.077	-0.802	0.48	0.01
24	0.409	-0.814	-0.414	0.33
25	-0.046	-0.281	-0.636	0.566
26	-0.461	0.41	-0.155	0.006

Standard thresholds

P-value	Threshold
0.001	0.53111
0.0005	2.03166
0.0001	5.14061