FLYWCH1.H13INVIVO.0.PSGB.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FLYWCH1.H13INVIVO.0.PSGB.A
Gene (human)	FLYWCH1 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Flywch1
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	15
Consensus	YWTTCKvYYYbhYYS
GC content	46.21%
Information content (bits; total / per base)	10.796 / 0.72
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + PBM
Aligned words	497
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (4)	0.667	0.678	0.509	0.519	0.736	0.795	19.078	30.244

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 1 experiments	median	0.974	0.957	0.953	0.93	0.868	0.85
GFPIVT, 1 experiments	best	0.974	0.957	0.953	0.93	0.868	0.85

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 3 experiments	median	8.886	0.98	0.656	0.5
overall, 3 experiments	best	18.553	0.995	0.688	0.612
Lysate, 2 experiments	median	12.399	0.978	0.659	0.493
Lysate, 2 experiments	best	18.553	0.98	0.673	0.532
GFPIVT, 1 experiments	median	8.886	0.992	0.656	0.5
GFPIVT, 1 experiments	best	13.921	0.995	0.688	0.612

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 2 experiments	median	0.647	0.005	0.633	0.004
Overall, 2 experiments	best	0.647	0.005	0.633	0.004

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	FLYWCH {2.3.4.255} (TFClass)
TFClass ID	TFClass: 2.3.4.255.1
HGNC
MGI
EntrezGene (human)
EntrezGene (mouse)
UniProt ID (human)	FWCH1_HUMAN
UniProt ID (mouse)	FWCH1_MOUSE
UniProt AC (human)	Q4VC44 (TFClass)
UniProt AC (mouse)	Q8CI03 (TFClass)
GRECO-DB-TF	no

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	3 overall: 2 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	0
PBM	2

PCM	FLYWCH1.H13INVIVO.0.PSGB.A.pcm
PWM	FLYWCH1.H13INVIVO.0.PSGB.A.pwm
PFM	FLYWCH1.H13INVIVO.0.PSGB.A.pfm
Threshold to P-value map	FLYWCH1.H13INVIVO.0.PSGB.A.thr
Motif in other formats
JASPAR format	FLYWCH1.H13INVIVO.0.PSGB.A_jaspar_format.txt
MEME format	FLYWCH1.H13INVIVO.0.PSGB.A_meme_format.meme
Transfac format	FLYWCH1.H13INVIVO.0.PSGB.A_transfac_format.txt
Homer format	FLYWCH1.H13INVIVO.0.PSGB.A_homer_format_0.001.txt FLYWCH1.H13INVIVO.0.PSGB.A_homer_format_0.0005.txt FLYWCH1.H13INVIVO.0.PSGB.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	25.0	283.0	70.0	119.0
02	142.0	58.0	25.0	272.0
03	1.0	28.0	12.0	456.0
04	1.0	13.0	5.0	478.0
05	2.0	478.0	5.0	12.0
06	16.0	60.0	245.0	176.0
07	197.0	88.0	132.0	80.0
08	28.0	167.0	24.0	278.0
09	18.0	115.0	46.0	318.0
10	24.0	365.0	26.0	82.0
11	20.0	211.0	76.0	190.0
12	161.0	85.0	57.0	194.0
13	32.0	94.0	34.0	337.0
14	13.0	176.0	37.0	271.0
15	9.0	353.0	77.0	58.0

PFM

	A	C	G	T
01	0.05	0.569	0.141	0.239
02	0.286	0.117	0.05	0.547
03	0.002	0.056	0.024	0.918
04	0.002	0.026	0.01	0.962
05	0.004	0.962	0.01	0.024
06	0.032	0.121	0.493	0.354
07	0.396	0.177	0.266	0.161
08	0.056	0.336	0.048	0.559
09	0.036	0.231	0.093	0.64
10	0.048	0.734	0.052	0.165
11	0.04	0.425	0.153	0.382
12	0.324	0.171	0.115	0.39
13	0.064	0.189	0.068	0.678
14	0.026	0.354	0.074	0.545
15	0.018	0.71	0.155	0.117

PWM

	A	C	G	T
01	-1.556	0.816	-0.564	-0.043
02	0.132	-0.748	-1.556	0.777
03	-3.898	-1.449	-2.228	1.291
04	-3.898	-2.157	-2.955	1.338
05	-3.567	1.338	-2.955	-2.228
06	-1.97	-0.715	0.673	0.345
07	0.456	-0.34	0.06	-0.433
08	-1.449	0.293	-1.594	0.798
09	-1.862	-0.076	-0.973	0.932
10	-1.594	1.069	-1.519	-0.409
11	-1.764	0.524	-0.484	0.42
12	0.256	-0.374	-0.765	0.441
13	-1.322	-0.275	-1.264	0.99
14	-2.157	0.345	-1.183	0.773
15	-2.478	1.036	-0.471	-0.748

Standard thresholds

P-value	Threshold
0.001	4.58946
0.0005	5.45501
0.0001	7.22536