FOS.H13RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOS.H13RSNP.0.P.B
Gene (human)	FOS (GeneCards)
Gene synonyms (human)	G0S7
Gene (mouse)	Fos
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	nTGAGTCAbnn
GC content	47.49%
Information content (bits; total / per base)	10.796 / 0.981
Data sources	ChIP-Seq
Aligned words	1000
Previous names	FOS.H12RSNP.0.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	25 (159)	0.866	0.989	0.825	0.963	0.87	0.99	3.63	5.187	241.319	588.699
Mouse	27 (180)	0.922	0.979	0.873	0.957	0.912	0.976	3.87	4.709	249.467	604.444

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 1 experiments	median	0.685	0.636	0.632	0.597	0.591	0.571
Non-Methyl HT-SELEX, 1 experiments	best	0.685	0.636	0.632	0.597	0.591	0.571

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.509	0.018	0.096	-0.028

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	Fos {1.1.2.1} (TFClass)
TFClass ID	TFClass: 1.1.2.1.1
HGNC	HGNC:3796
MGI	MGI:95574
EntrezGene (human)	GeneID:2353 (SSTAR profile)
EntrezGene (mouse)	GeneID:14281 (SSTAR profile)
UniProt ID (human)	FOS_HUMAN
UniProt ID (mouse)	FOS_MOUSE
UniProt AC (human)	P01100 (TFClass)
UniProt AC (mouse)	P01101 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	25 human, 27 mouse
HT-SELEX	1
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	FOS.H13RSNP.0.P.B.pcm
PWM	FOS.H13RSNP.0.P.B.pwm
PFM	FOS.H13RSNP.0.P.B.pfm
Threshold to P-value map	FOS.H13RSNP.0.P.B.thr
Motif in other formats
JASPAR format	FOS.H13RSNP.0.P.B_jaspar_format.txt
MEME format	FOS.H13RSNP.0.P.B_meme_format.meme
Transfac format	FOS.H13RSNP.0.P.B_transfac_format.txt
Homer format	FOS.H13RSNP.0.P.B_homer_format_0.001.txt FOS.H13RSNP.0.P.B_homer_format_0.0005.txt FOS.H13RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	284.0	289.0	270.0	157.0
02	26.0	1.0	13.0	960.0
03	10.0	10.0	878.0	102.0
04	828.0	52.0	21.0	99.0
05	59.0	0.0	941.0	0.0
06	30.0	37.0	71.0	862.0
07	72.0	910.0	12.0	6.0
08	989.0	6.0	3.0	2.0
09	57.0	389.0	270.0	284.0
10	274.0	352.0	142.0	232.0
11	251.0	242.0	315.0	192.0

PFM

	A	C	G	T
01	0.284	0.289	0.27	0.157
02	0.026	0.001	0.013	0.96
03	0.01	0.01	0.878	0.102
04	0.828	0.052	0.021	0.099
05	0.059	0.0	0.941	0.0
06	0.03	0.037	0.071	0.862
07	0.072	0.91	0.012	0.006
08	0.989	0.006	0.003	0.002
09	0.057	0.389	0.27	0.284
10	0.274	0.352	0.142	0.232
11	0.251	0.242	0.315	0.192

PWM

	A	C	G	T
01	0.127	0.144	0.076	-0.461
02	-2.206	-4.525	-2.839	1.34
03	-3.066	-3.066	1.251	-0.887
04	1.193	-1.544	-2.405	-0.916
05	-1.422	-4.982	1.32	-4.982
06	-2.071	-1.872	-1.242	1.233
07	-1.228	1.287	-2.909	-3.484
08	1.37	-3.484	-3.975	-4.213
09	-1.455	0.44	0.076	0.127
10	0.091	0.34	-0.56	-0.074
11	0.004	-0.032	0.23	-0.262

Standard thresholds

P-value	Threshold
0.001	4.49756
0.0005	5.468135
0.0001	7.19734