FOSB.H13CORE.1.M.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	FOSB.H13CORE.1.M.C
Gene (human)	FOSB (GeneCards)
Gene synonyms (human)	G0S3
Gene (mouse)	Fosb
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	11
Consensus	nvhGTCATMvn
GC content	48.65%
Information content (bits; total / per base)	10.156 / 0.923
Data sources	Methyl-HT-SELEX
Aligned words	8359
Previous names	FOSB.H12CORE.1.M.C

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.84	0.853	0.694	0.702	0.74	0.756	1.926	2.028	152.86	195.328
Mouse	4 (27)	0.71	0.745	0.539	0.593	0.622	0.658	1.419	1.565	28.538	47.046

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Methyl HT-SELEX, 1 experiments	median	0.937	0.91	0.861	0.831	0.734	0.73
Methyl HT-SELEX, 1 experiments	best	0.937	0.91	0.861	0.831	0.734	0.73

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Fos-related {1.1.2} (TFClass)
TF subfamily	Fos {1.1.2.1} (TFClass)
TFClass ID	TFClass: 1.1.2.1.2
HGNC	HGNC:3797
MGI	MGI:95575
EntrezGene (human)	GeneID:2354 (SSTAR profile)
EntrezGene (mouse)	GeneID:14282 (SSTAR profile)
UniProt ID (human)	FOSB_HUMAN
UniProt ID (mouse)	FOSB_MOUSE
UniProt AC (human)	P53539 (TFClass)
UniProt AC (mouse)	P13346 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 4 mouse
HT-SELEX	0
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	FOSB.H13CORE.1.M.C.pcm
PWM	FOSB.H13CORE.1.M.C.pwm
PFM	FOSB.H13CORE.1.M.C.pfm
Threshold to P-value map	FOSB.H13CORE.1.M.C.thr
Motif in other formats
JASPAR format	FOSB.H13CORE.1.M.C_jaspar_format.txt
MEME format	FOSB.H13CORE.1.M.C_meme_format.meme
Transfac format	FOSB.H13CORE.1.M.C_transfac_format.txt
Homer format	FOSB.H13CORE.1.M.C_homer_format_0.001.txt FOSB.H13CORE.1.M.C_homer_format_0.0005.txt FOSB.H13CORE.1.M.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1580.5	1888.5	2543.5	2346.5
02	3077.0	1426.0	2717.0	1139.0
03	1656.0	4440.0	473.0	1790.0
04	521.0	284.0	7552.0	2.0
05	0.0	0.0	0.0	8359.0
06	10.0	8349.0	0.0	0.0
07	8242.0	117.0	0.0	0.0
08	0.0	502.0	8.0	7849.0
09	1546.0	5068.0	668.0	1077.0
10	3402.75	1729.75	2574.75	651.75
11	1638.25	2900.25	1490.25	2330.25

PFM

	A	C	G	T
01	0.189	0.226	0.304	0.281
02	0.368	0.171	0.325	0.136
03	0.198	0.531	0.057	0.214
04	0.062	0.034	0.903	0.0
05	0.0	0.0	0.0	1.0
06	0.001	0.999	0.0	0.0
07	0.986	0.014	0.0	0.0
08	0.0	0.06	0.001	0.939
09	0.185	0.606	0.08	0.129
10	0.407	0.207	0.308	0.078
11	0.196	0.347	0.178	0.279

PWM

	A	C	G	T
01	-0.279	-0.101	0.196	0.116
02	0.387	-0.382	0.262	-0.606
03	-0.232	0.753	-1.482	-0.155
04	-1.386	-1.989	1.284	-6.197
05	-6.832	-6.832	-6.832	1.385
06	-5.14	1.384	-6.832	-6.832
07	1.371	-2.865	-6.832	-6.832
08	-6.832	-1.423	-5.318	1.323
09	-0.301	0.885	-1.138	-0.662
10	0.487	-0.189	0.209	-1.163
11	-0.243	0.327	-0.338	0.109

Standard thresholds

P-value	Threshold
0.001	4.892665
0.0005	5.968245
0.0001	7.61993