MotifGATA2.H13RSNP.1.P.B
Gene (human)GATA2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Gata2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length19
ConsensusvnKbnnnnndvAGATAARv
GC content45.15%
Information content (bits; total / per base)11.704 / 0.616
Data sourcesChIP-Seq
Aligned words1005
Previous namesGATA2.H12RSNP.1.P.B

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 41 (254) 0.835 0.952 0.7 0.898 0.823 0.945 2.567 4.269 162.915 316.469
Mouse 23 (136) 0.786 0.955 0.66 0.898 0.778 0.954 2.408 4.266 127.111 329.237

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.907 0.852 0.877 0.821 0.824 0.774
best 0.919 0.867 0.896 0.842 0.853 0.801
Methyl HT-SELEX, 1 experiments median 0.919 0.867 0.896 0.842 0.853 0.801
best 0.919 0.867 0.896 0.842 0.853 0.801
Non-Methyl HT-SELEX, 1 experiments median 0.894 0.837 0.857 0.799 0.794 0.747
best 0.894 0.837 0.857 0.799 0.794 0.747

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 4.624 5.538 0.238 0.129

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.636 0.29 0.615 0.441
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classOther C4 zinc finger-type factors {2.2} (TFClass)
TF familyC4-GATA-related {2.2.1} (TFClass)
TF subfamilyGATA double {2.2.1.1} (TFClass)
TFClass IDTFClass: 2.2.1.1.2
HGNCHGNC:4171
MGIMGI:95662
EntrezGene (human)GeneID:2624
(SSTAR profile)
EntrezGene (mouse)GeneID:14461
(SSTAR profile)
UniProt ID (human)GATA2_HUMAN
UniProt ID (mouse)GATA2_MOUSE
UniProt AC (human)P23769
(TFClass)
UniProt AC (mouse)O09100
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 41 human, 23 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01188.0394.0255.0168.0
02149.0189.0149.0518.0
0389.060.0565.0291.0
04134.0210.0457.0204.0
05225.0205.0306.0269.0
06286.0207.0292.0220.0
07277.0174.0324.0230.0
08296.0213.0313.0183.0
09217.0267.0279.0242.0
10373.0136.0345.0151.0
11163.0411.0353.078.0
12724.013.011.0257.0
131.00.01004.00.0
14998.04.02.01.0
154.08.010.0983.0
16950.03.08.044.0
17856.012.0114.023.0
18177.0160.0596.072.0
19370.0187.0385.063.0
PFM
ACGT
010.1870.3920.2540.167
020.1480.1880.1480.515
030.0890.060.5620.29
040.1330.2090.4550.203
050.2240.2040.3040.268
060.2850.2060.2910.219
070.2760.1730.3220.229
080.2950.2120.3110.182
090.2160.2660.2780.241
100.3710.1350.3430.15
110.1620.4090.3510.078
120.720.0130.0110.256
130.0010.00.9990.0
140.9930.0040.0020.001
150.0040.0080.010.978
160.9450.0030.0080.044
170.8520.0120.1130.023
180.1760.1590.5930.072
190.3680.1860.3830.063
PWM
ACGT
01-0.2880.4470.015-0.399
02-0.518-0.282-0.5180.72
03-1.025-1.4110.8070.146
04-0.623-0.1780.595-0.207
05-0.11-0.2020.1960.068
060.129-0.1920.149-0.132
070.097-0.3640.253-0.088
080.163-0.1640.218-0.314
09-0.1450.060.104-0.037
100.393-0.6080.315-0.505
11-0.4290.4890.338-1.155
121.054-2.844-2.9890.022
13-4.53-4.9861.38-4.986
141.374-3.788-4.217-4.53
15-3.788-3.258-3.0711.359
161.325-3.98-3.258-1.711
171.221-2.914-0.782-2.325
18-0.347-0.4470.86-1.233
190.385-0.2930.424-1.363
Standard thresholds
P-value Threshold
0.001 4.17936
0.0005 5.26851
0.0001 7.41851