| Motif | GCR.H13RSNP.1.S.B |
| Gene (human) | NR3C1 (GeneCards) |
| Gene synonyms (human) | GRL |
| Gene (mouse) | Nr3c1 |
| Gene synonyms (mouse) | Grl, Grl1 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | B |
| Motif | GCR.H13RSNP.1.S.B |
| Gene (human) | NR3C1 (GeneCards) |
| Gene synonyms (human) | GRL |
| Gene (mouse) | Nr3c1 |
| Gene synonyms (mouse) | Grl, Grl1 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | B |
| Motif length | 9 |
| Consensus | nvTGTWCbn |
| GC content | 45.4% |
| Information content (bits; total / per base) | 7.476 / 0.831 |
| Data sources | HT-SELEX |
| Aligned words | 8247 |
| Previous names | GCR.H12RSNP.1.S.B |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 82 (479) | 0.778 | 0.895 | 0.621 | 0.794 | 0.714 | 0.799 | 1.783 | 2.089 | 74.222 | 227.523 |
| Mouse | 93 (512) | 0.737 | 0.83 | 0.571 | 0.7 | 0.701 | 0.796 | 1.714 | 2.077 | 68.128 | 238.301 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.756 | 0.723 | 0.653 | 0.639 | 0.587 | 0.588 |
| best | 0.819 | 0.794 | 0.687 | 0.68 | 0.605 | 0.612 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 2.75 | 17.745 | 0.131 | 0.055 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | Nuclear receptors with C4 zinc fingers {2.1} (TFClass) |
| TF family | Steroid hormone receptors {2.1.1} (TFClass) |
| TF subfamily | GR-like (NR3C) {2.1.1.1} (TFClass) |
| TFClass ID | TFClass: 2.1.1.1.1 |
| HGNC | HGNC:7978 |
| MGI | MGI:95824 |
| EntrezGene (human) | GeneID:2908 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | GCR_HUMAN |
| UniProt ID (mouse) | GCR_MOUSE |
| UniProt AC (human) | P04150 (TFClass) |
| UniProt AC (mouse) | P06537 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 82 human, 93 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | GCR.H13RSNP.1.S.B.pcm |
| PWM | GCR.H13RSNP.1.S.B.pwm |
| PFM | GCR.H13RSNP.1.S.B.pfm |
| Threshold to P-value map | GCR.H13RSNP.1.S.B.thr |
| Motif in other formats | |
| JASPAR format | GCR.H13RSNP.1.S.B_jaspar_format.txt |
| MEME format | GCR.H13RSNP.1.S.B_meme_format.meme |
| Transfac format | GCR.H13RSNP.1.S.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 2506.25 | 2146.25 | 1494.25 | 2100.25 |
| 02 | 3831.25 | 1218.25 | 2376.25 | 821.25 |
| 03 | 573.0 | 938.0 | 119.0 | 6617.0 |
| 04 | 0.0 | 1.0 | 8244.0 | 2.0 |
| 05 | 39.0 | 26.0 | 0.0 | 8182.0 |
| 06 | 2986.0 | 638.0 | 266.0 | 4357.0 |
| 07 | 119.0 | 7581.0 | 43.0 | 504.0 |
| 08 | 777.25 | 3147.25 | 1331.25 | 2991.25 |
| 09 | 1589.0 | 2311.0 | 1815.0 | 2532.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.304 | 0.26 | 0.181 | 0.255 |
| 02 | 0.465 | 0.148 | 0.288 | 0.1 |
| 03 | 0.069 | 0.114 | 0.014 | 0.802 |
| 04 | 0.0 | 0.0 | 1.0 | 0.0 |
| 05 | 0.005 | 0.003 | 0.0 | 0.992 |
| 06 | 0.362 | 0.077 | 0.032 | 0.528 |
| 07 | 0.014 | 0.919 | 0.005 | 0.061 |
| 08 | 0.094 | 0.382 | 0.161 | 0.363 |
| 09 | 0.193 | 0.28 | 0.22 | 0.307 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.195 | 0.04 | -0.322 | 0.018 |
| 02 | 0.619 | -0.525 | 0.142 | -0.919 |
| 03 | -1.278 | -0.786 | -2.835 | 1.165 |
| 04 | -6.82 | -6.452 | 1.385 | -6.184 |
| 05 | -3.913 | -4.291 | -6.82 | 1.378 |
| 06 | 0.37 | -1.171 | -2.04 | 0.748 |
| 07 | -2.835 | 1.301 | -3.82 | -1.405 |
| 08 | -0.974 | 0.423 | -0.437 | 0.372 |
| 09 | -0.26 | 0.114 | -0.127 | 0.205 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.408185 |
| 0.0005 | 6.045875 |
| 0.0001 | 6.874235 |