GRHL3.H13INVIVO.0.SB.D motif - HOmo sapiens COmprehensive MOdel COllection

Motif	GRHL3.H13INVIVO.0.SB.D
Gene (human)	GRHL3 (GeneCards)
Gene synonyms (human)	SOM, TFCP2L4
Gene (mouse)	Grhl3
Gene synonyms (mouse)	Get1, Som, Tfcp2l4
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	D

Motif length	18
Consensus	dYhdGhhnRACCGGTYhn
GC content	52.56%
Information content (bits; total / per base)	14.438 / 0.802
Data sources	HT-SELEX + PBM
Aligned words	453
Previous names

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
IVT, 1 experiments	median	0.856	0.832	0.721	0.711	0.625	0.633
IVT, 1 experiments	best	0.856	0.832	0.721	0.711	0.625	0.633

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 4 experiments	median	0.797	0.055	0.731	0.035
Overall, 4 experiments	best	0.814	0.064	0.779	0.051

TF superclass	Immunoglobulin fold {6} (TFClass)
TF class	Grainyhead domain factors {6.7} (TFClass)
TF family	Grainyhead-related {6.7.1} (TFClass)
TF subfamily	GRH-like {6.7.1.1} (TFClass)
TFClass ID	TFClass: 6.7.1.1.3
HGNC	HGNC:25839
MGI	MGI:2655333
EntrezGene (human)	GeneID:57822 (SSTAR profile)
EntrezGene (mouse)	GeneID:230824 (SSTAR profile)
UniProt ID (human)	GRHL3_HUMAN
UniProt ID (mouse)	GRHL3_MOUSE
UniProt AC (human)	Q8TE85 (TFClass)
UniProt AC (mouse)	Q5FWH3 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 1 IVT, 0 GFPIVT
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	4

PCM	GRHL3.H13INVIVO.0.SB.D.pcm
PWM	GRHL3.H13INVIVO.0.SB.D.pwm
PFM	GRHL3.H13INVIVO.0.SB.D.pfm
Threshold to P-value map	GRHL3.H13INVIVO.0.SB.D.thr
Motif in other formats
JASPAR format	GRHL3.H13INVIVO.0.SB.D_jaspar_format.txt
MEME format	GRHL3.H13INVIVO.0.SB.D_meme_format.meme
Transfac format	GRHL3.H13INVIVO.0.SB.D_transfac_format.txt
Homer format	GRHL3.H13INVIVO.0.SB.D_homer_format_0.001.txt GRHL3.H13INVIVO.0.SB.D_homer_format_0.0005.txt GRHL3.H13INVIVO.0.SB.D_homer_format_0.0001.txt

PCM

	A	C	G	T
01	185.75	68.75	101.75	96.75
02	27.25	338.25	43.25	44.25
03	110.0	206.0	36.0	101.0
04	70.0	46.0	195.0	142.0
05	19.0	32.0	382.0	20.0
06	96.0	116.0	43.0	198.0
07	112.0	110.0	58.0	173.0
08	167.0	84.0	83.0	119.0
09	335.0	11.0	76.0	31.0
10	435.0	0.0	8.0	10.0
11	0.0	453.0	0.0	0.0
12	50.0	397.0	0.0	6.0
13	6.0	0.0	417.0	30.0
14	0.0	0.0	452.0	1.0
15	28.0	18.0	6.0	401.0
16	35.0	76.0	18.0	324.0
17	100.0	116.0	64.0	173.0
18	106.25	121.25	109.25	116.25

PFM

	A	C	G	T
01	0.41	0.152	0.225	0.214
02	0.06	0.747	0.095	0.098
03	0.243	0.455	0.079	0.223
04	0.155	0.102	0.43	0.313
05	0.042	0.071	0.843	0.044
06	0.212	0.256	0.095	0.437
07	0.247	0.243	0.128	0.382
08	0.369	0.185	0.183	0.263
09	0.74	0.024	0.168	0.068
10	0.96	0.0	0.018	0.022
11	0.0	1.0	0.0	0.0
12	0.11	0.876	0.0	0.013
13	0.013	0.0	0.921	0.066
14	0.0	0.0	0.998	0.002
15	0.062	0.04	0.013	0.885
16	0.077	0.168	0.04	0.715
17	0.221	0.256	0.141	0.382
18	0.235	0.268	0.241	0.257

PWM

	A	C	G	T
01	0.49	-0.491	-0.106	-0.155
02	-1.383	1.085	-0.941	-0.919
03	-0.029	0.592	-1.118	-0.113
04	-0.473	-0.882	0.538	0.224
05	-1.721	-1.231	1.206	-1.674
06	-0.163	0.024	-0.947	0.553
07	-0.011	-0.029	-0.657	0.419
08	0.384	-0.294	-0.306	0.049
09	1.076	-2.215	-0.392	-1.261
10	1.336	-4.318	-2.489	-2.298
11	-4.318	1.376	-4.318	-4.318
12	-0.801	1.245	-4.318	-2.724
13	-2.724	-4.318	1.294	-1.292
14	-4.318	-4.318	1.374	-3.815
15	-1.358	-1.771	-2.724	1.255
16	-1.145	-0.392	-1.771	1.042
17	-0.123	0.024	-0.561	0.419
18	-0.063	0.067	-0.035	0.026

Standard thresholds

P-value	Threshold
0.001	3.33691
0.0005	4.47541
0.0001	6.81826