HEY2.H13CORE.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	HEY2.H13CORE.0.S.B
Gene (human)	HEY2 (GeneCards)
Gene synonyms (human)	BHLHB32, CHF1, GRL, HERP, HERP1, HRT2
Gene (mouse)	Hey2
Gene synonyms (mouse)	Chf1, Herp, Herp1, Hesr2, Hrt2
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	13
Consensus	nKGCACGTGYYnn
GC content	63.41%
Information content (bits; total / per base)	15.703 / 1.208
Data sources	HT-SELEX
Aligned words	1695
Previous names	HEY2.H12CORE.0.S.B

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 5 experiments	median	0.886	0.86	0.779	0.754	0.682	0.673
Non-Methyl HT-SELEX, 5 experiments	best	0.994	0.99	0.988	0.982	0.915	0.909

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.811	0.686	0.823	0.622

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	Hairy-related {1.2.4} (TFClass)
TF subfamily	HAIRY {1.2.4.1} (TFClass)
TFClass ID	TFClass: 1.2.4.1.9
HGNC	HGNC:4881
MGI	MGI:1341884
EntrezGene (human)	GeneID:23493 (SSTAR profile)
EntrezGene (mouse)	GeneID:15214 (SSTAR profile)
UniProt ID (human)	HEY2_HUMAN
UniProt ID (mouse)	HEY2_MOUSE
UniProt AC (human)	Q9UBP5 (TFClass)
UniProt AC (mouse)	Q9QUS4 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	5
Methyl-HT-SELEX	0
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	HEY2.H13CORE.0.S.B.pcm
PWM	HEY2.H13CORE.0.S.B.pwm
PFM	HEY2.H13CORE.0.S.B.pfm
Threshold to P-value map	HEY2.H13CORE.0.S.B.thr
Motif in other formats
JASPAR format	HEY2.H13CORE.0.S.B_jaspar_format.txt
MEME format	HEY2.H13CORE.0.S.B_meme_format.meme
Transfac format	HEY2.H13CORE.0.S.B_transfac_format.txt
Homer format	HEY2.H13CORE.0.S.B_homer_format_0.001.txt HEY2.H13CORE.0.S.B_homer_format_0.0005.txt HEY2.H13CORE.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	435.75	347.75	538.75	372.75
02	110.5	192.5	1125.5	266.5
03	47.0	86.0	1534.0	28.0
04	0.0	1695.0	0.0	0.0
05	1695.0	0.0	0.0	0.0
06	0.0	1695.0	0.0	0.0
07	0.0	0.0	1695.0	0.0
08	0.0	0.0	0.0	1695.0
09	0.0	0.0	1695.0	0.0
10	0.0	347.0	200.0	1148.0
11	72.0	1237.0	56.0	330.0
12	490.75	372.75	268.75	562.75
13	372.25	465.25	421.25	436.25

PFM

	A	C	G	T
01	0.257	0.205	0.318	0.22
02	0.065	0.114	0.664	0.157
03	0.028	0.051	0.905	0.017
04	0.0	1.0	0.0	0.0
05	1.0	0.0	0.0	0.0
06	0.0	1.0	0.0	0.0
07	0.0	0.0	1.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	0.0	1.0	0.0
10	0.0	0.205	0.118	0.677
11	0.042	0.73	0.033	0.195
12	0.29	0.22	0.159	0.332
13	0.22	0.274	0.249	0.257

PWM

	A	C	G	T
01	0.028	-0.197	0.239	-0.128
02	-1.332	-0.784	0.974	-0.461
03	-2.165	-1.578	1.283	-2.657
04	-5.434	1.383	-5.434	-5.434
05	1.383	-5.434	-5.434	-5.434
06	-5.434	1.383	-5.434	-5.434
07	-5.434	-5.434	1.383	-5.434
08	-5.434	-5.434	-5.434	1.383
09	-5.434	-5.434	1.383	-5.434
10	-5.434	-0.199	-0.746	0.994
11	-1.751	1.068	-1.996	-0.249
12	0.146	-0.128	-0.453	0.283
13	-0.129	0.093	-0.006	0.029

Standard thresholds

P-value	Threshold
0.001	0.66021
0.0005	2.289755
0.0001	5.74007