MotifHME1.H13INVITRO.0.PSM.A
Gene (human)EN1
(GeneCards)
Gene synonyms (human)
Gene (mouse)En1
Gene synonyms (mouse)En-1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length11
ConsensusnbYAATTAvbn
GC content34.92%
Information content (bits; total / per base)11.077 / 1.007
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words2185
Previous namesHME1.H12INVITRO.0.PSM.A

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (2) 0.739 0.739 0.62 0.62 0.7 0.7 2.016 2.016 10.699 10.699

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 6 experiments median 0.925 0.896 0.808 0.788 0.676 0.685
best 0.959 0.931 0.938 0.905 0.894 0.857
Methyl HT-SELEX, 1 experiments median 0.959 0.931 0.938 0.905 0.892 0.857
best 0.959 0.931 0.938 0.905 0.892 0.857
Non-Methyl HT-SELEX, 5 experiments median 0.92 0.889 0.801 0.781 0.672 0.68
best 0.95 0.917 0.931 0.893 0.894 0.853
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyEN {3.1.2.7} (TFClass)
TFClass IDTFClass: 3.1.2.7.1
HGNCHGNC:3342
MGIMGI:95389
EntrezGene (human)GeneID:2019
(SSTAR profile)
EntrezGene (mouse)GeneID:13798
(SSTAR profile)
UniProt ID (human)HME1_HUMAN
UniProt ID (mouse)HME1_MOUSE
UniProt AC (human)Q05925
(TFClass)
UniProt AC (mouse)P09065
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01633.75727.75453.75369.75
02232.01093.0604.0256.0
0310.01000.00.01175.0
042055.0127.00.03.0
052174.00.011.00.0
060.00.00.02185.0
070.0145.00.02040.0
082153.00.032.00.0
09710.0585.0794.096.0
1077.01112.0444.0552.0
11474.5575.5688.5446.5
PFM
ACGT
010.290.3330.2080.169
020.1060.50.2760.117
030.0050.4580.00.538
040.9410.0580.00.001
050.9950.00.0050.0
060.00.00.01.0
070.00.0660.00.934
080.9850.00.0150.0
090.3250.2680.3630.044
100.0350.5090.2030.253
110.2170.2630.3150.204
PWM
ACGT
010.1480.286-0.185-0.389
02-0.8520.6920.1-0.754
03-3.8280.603-5.6530.764
041.322-1.447-5.653-4.713
051.379-5.653-3.748-5.653
06-5.653-5.653-5.6531.384
07-5.653-1.317-5.6531.315
081.369-5.653-2.783-5.653
090.2610.0680.373-1.722
10-1.9380.709-0.2060.01
11-0.140.0520.231-0.201
Standard thresholds
P-value Threshold
0.001 4.16126
0.0005 5.51405
0.0001 7.904885