| Motif | KDM2A.H13INVIVO.0.PSGB.A |
| Gene (human) | KDM2A (GeneCards) |
| Gene synonyms (human) | CXXC8, FBL11, FBL7, FBXL11, JHDM1A, KIAA1004 |
| Gene (mouse) | Kdm2a |
| Gene synonyms (mouse) | Fbl11, Fbxl11, Jhdm1a, Kiaa1004 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 21 |
| Consensus | hbSnbYYYbbSSbbCbbCTSC |
| GC content | 69.1% |
| Information content (bits; total / per base) | 11.61 / 0.553 |
| Data sources | ChIP-Seq + HT-SELEX + Genomic HT-SELEX + PBM |
| Aligned words | 500 |
| Previous names |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|
| Overall | 2 (4) | 0.718 | 0.728 | 0.486 | 0.504 | 0.684 | 0.707 | 0.25 | 1.056 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| overall, 2 experiments | median | 0.446 | 0.472 | 0.455 | 0.476 | 0.464 | 0.479 |
| best | 0.488 | 0.493 | 0.493 | 0.495 | 0.497 | 0.497 | |
| Lysate, 1 experiments | median | 0.404 | 0.45 | 0.417 | 0.456 | 0.43 | 0.461 |
| best | 0.404 | 0.45 | 0.417 | 0.456 | 0.43 | 0.461 | |
| GFPIVT, 1 experiments | median | 0.488 | 0.493 | 0.493 | 0.495 | 0.497 | 0.497 |
| best | 0.488 | 0.493 | 0.493 | 0.495 | 0.497 | 0.497 | |
| Genomic HT-SELEX benchmarking | Centrality | pseudo-auROC | auROC | auPR | |
|---|---|---|---|---|---|
| Lysate, 1 experiments | median | 0.0 | 0.651 | 0.609 | 0.406 |
| best | 0.0 | 0.651 | 0.609 | 0.406 | |
| PBM benchmarking | auROC, QNZS | auPR, QNZS | auROC, SD | auPR, SD | |
|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.555 | 0.002 | 0.429 | 0.003 |
| best | 0.634 | 0.002 | 0.446 | 0.004 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | CXXC zinc finger factors {2.6} (TFClass) |
| TF family | CpG-binding {2.6.1} (TFClass) |
| TF subfamily | {2.6.1.0} (TFClass) |
| TFClass ID | TFClass: 2.6.1.0.5 |
| HGNC | HGNC:13606 |
| MGI | MGI:1354736 |
| EntrezGene (human) | GeneID:22992 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:225876 (SSTAR profile) |
| UniProt ID (human) | KDM2A_HUMAN |
| UniProt ID (mouse) | KDM2A_MOUSE |
| UniProt AC (human) | Q9Y2K7 (TFClass) |
| UniProt AC (mouse) | P59997 (TFClass) |
| GRECO-DB-TF | no |
| ChIP-Seq | 2 human, 0 mouse |
| HT-SELEX | 2 overall: 1 Lysate, 0 IVT, 1 GFPIVT |
| Genomic HT-SELEX | 1 overall: 1 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 4 |
| PCM | KDM2A.H13INVIVO.0.PSGB.A.pcm |
| PWM | KDM2A.H13INVIVO.0.PSGB.A.pwm |
| PFM | KDM2A.H13INVIVO.0.PSGB.A.pfm |
| Threshold to P-value map | KDM2A.H13INVIVO.0.PSGB.A.thr |
| Motif in other formats | |
| JASPAR format | KDM2A.H13INVIVO.0.PSGB.A_jaspar_format.txt |
| MEME format | KDM2A.H13INVIVO.0.PSGB.A_meme_format.meme |
| Transfac format | KDM2A.H13INVIVO.0.PSGB.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 64.0 | 267.0 | 37.0 | 132.0 |
| 02 | 25.0 | 127.0 | 233.0 | 115.0 |
| 03 | 42.0 | 353.0 | 77.0 | 28.0 |
| 04 | 118.0 | 118.0 | 87.0 | 177.0 |
| 05 | 21.0 | 145.0 | 247.0 | 87.0 |
| 06 | 16.0 | 332.0 | 28.0 | 124.0 |
| 07 | 19.0 | 122.0 | 81.0 | 278.0 |
| 08 | 13.0 | 299.0 | 72.0 | 116.0 |
| 09 | 37.0 | 239.0 | 105.0 | 119.0 |
| 10 | 36.0 | 195.0 | 134.0 | 135.0 |
| 11 | 7.0 | 252.0 | 196.0 | 45.0 |
| 12 | 13.0 | 397.0 | 49.0 | 41.0 |
| 13 | 48.0 | 128.0 | 148.0 | 176.0 |
| 14 | 20.0 | 168.0 | 232.0 | 80.0 |
| 15 | 16.0 | 407.0 | 20.0 | 57.0 |
| 16 | 36.0 | 124.0 | 159.0 | 181.0 |
| 17 | 26.0 | 151.0 | 241.0 | 82.0 |
| 18 | 16.0 | 424.0 | 26.0 | 34.0 |
| 19 | 11.0 | 7.0 | 16.0 | 466.0 |
| 20 | 5.0 | 273.0 | 140.0 | 82.0 |
| 21 | 26.0 | 393.0 | 7.0 | 74.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.128 | 0.534 | 0.074 | 0.264 |
| 02 | 0.05 | 0.254 | 0.466 | 0.23 |
| 03 | 0.084 | 0.706 | 0.154 | 0.056 |
| 04 | 0.236 | 0.236 | 0.174 | 0.354 |
| 05 | 0.042 | 0.29 | 0.494 | 0.174 |
| 06 | 0.032 | 0.664 | 0.056 | 0.248 |
| 07 | 0.038 | 0.244 | 0.162 | 0.556 |
| 08 | 0.026 | 0.598 | 0.144 | 0.232 |
| 09 | 0.074 | 0.478 | 0.21 | 0.238 |
| 10 | 0.072 | 0.39 | 0.268 | 0.27 |
| 11 | 0.014 | 0.504 | 0.392 | 0.09 |
| 12 | 0.026 | 0.794 | 0.098 | 0.082 |
| 13 | 0.096 | 0.256 | 0.296 | 0.352 |
| 14 | 0.04 | 0.336 | 0.464 | 0.16 |
| 15 | 0.032 | 0.814 | 0.04 | 0.114 |
| 16 | 0.072 | 0.248 | 0.318 | 0.362 |
| 17 | 0.052 | 0.302 | 0.482 | 0.164 |
| 18 | 0.032 | 0.848 | 0.052 | 0.068 |
| 19 | 0.022 | 0.014 | 0.032 | 0.932 |
| 20 | 0.01 | 0.546 | 0.28 | 0.164 |
| 21 | 0.052 | 0.786 | 0.014 | 0.148 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.658 | 0.752 | -1.189 | 0.054 |
| 02 | -1.561 | 0.016 | 0.617 | -0.082 |
| 03 | -1.067 | 1.03 | -0.477 | -1.454 |
| 04 | -0.057 | -0.057 | -0.357 | 0.344 |
| 05 | -1.725 | 0.147 | 0.675 | -0.357 |
| 06 | -1.975 | 0.969 | -1.454 | -0.008 |
| 07 | -1.818 | -0.024 | -0.427 | 0.793 |
| 08 | -2.163 | 0.865 | -0.543 | -0.074 |
| 09 | -1.189 | 0.642 | -0.172 | -0.049 |
| 10 | -1.215 | 0.44 | 0.069 | 0.076 |
| 11 | -2.694 | 0.695 | 0.445 | -1.0 |
| 12 | -2.163 | 1.147 | -0.918 | -1.09 |
| 13 | -0.938 | 0.023 | 0.167 | 0.339 |
| 14 | -1.77 | 0.293 | 0.613 | -0.439 |
| 15 | -1.975 | 1.172 | -1.77 | -0.771 |
| 16 | -1.215 | -0.008 | 0.238 | 0.366 |
| 17 | -1.525 | 0.187 | 0.651 | -0.415 |
| 18 | -1.975 | 1.213 | -1.525 | -1.27 |
| 19 | -2.311 | -2.694 | -1.975 | 1.307 |
| 20 | -2.961 | 0.774 | 0.112 | -0.415 |
| 21 | -1.525 | 1.137 | -2.694 | -0.516 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.39021 |
| 0.0005 | 5.25891 |
| 0.0001 | 7.08241 |