KLF11.H13RSNP.1.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF11.H13RSNP.1.SM.B
Gene (human)	KLF11 (GeneCards)
Gene synonyms (human)	FKLF, TIEG2
Gene (mouse)	Klf11
Gene synonyms (mouse)	Tieg2b, Tieg3
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	25
Consensus	ndnRKGGGCGTGKvRKGGGSGKKKb
GC content	73.22%
Information content (bits; total / per base)	25.529 / 1.021
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	1718
Previous names	KLF11.H12RSNP.1.SM.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.655	0.678	0.454	0.499	0.731	0.743	2.371	2.608	4.21	7.036

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.995	0.992	0.989	0.983	0.95	0.942
Overall, 2 experiments	best	0.996	0.993	0.99	0.985	0.954	0.944
Methyl HT-SELEX, 1 experiments	median	0.994	0.991	0.987	0.981	0.954	0.944
Methyl HT-SELEX, 1 experiments	best	0.994	0.991	0.987	0.981	0.954	0.944
Non-Methyl HT-SELEX, 1 experiments	median	0.996	0.993	0.99	0.985	0.946	0.94
Non-Methyl HT-SELEX, 1 experiments	best	0.996	0.993	0.99	0.985	0.946	0.94

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.89	0.708	0.898	0.717

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.11
HGNC	HGNC:11811
MGI	MGI:2653368
EntrezGene (human)	GeneID:8462 (SSTAR profile)
EntrezGene (mouse)	GeneID:194655 (SSTAR profile)
UniProt ID (human)	KLF11_HUMAN
UniProt ID (mouse)	KLF11_MOUSE
UniProt AC (human)	O14901 (TFClass)
UniProt AC (mouse)	Q8K1S5 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	KLF11.H13RSNP.1.SM.B.pcm
PWM	KLF11.H13RSNP.1.SM.B.pwm
PFM	KLF11.H13RSNP.1.SM.B.pfm
Threshold to P-value map	KLF11.H13RSNP.1.SM.B.thr
Motif in other formats
JASPAR format	KLF11.H13RSNP.1.SM.B_jaspar_format.txt
MEME format	KLF11.H13RSNP.1.SM.B_meme_format.meme
Transfac format	KLF11.H13RSNP.1.SM.B_transfac_format.txt
Homer format	KLF11.H13RSNP.1.SM.B_homer_format_0.001.txt KLF11.H13RSNP.1.SM.B_homer_format_0.0005.txt KLF11.H13RSNP.1.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	417.0	313.0	642.0	346.0
02	460.5	194.5	705.5	357.5
03	474.0	302.0	565.0	377.0
04	318.0	58.0	1219.0	123.0
05	188.0	10.0	791.0	729.0
06	96.0	1.0	1620.0	1.0
07	0.0	0.0	1718.0	0.0
08	1.0	0.0	1717.0	0.0
09	26.0	1658.0	0.0	34.0
10	6.0	0.0	1710.0	2.0
11	7.0	2.0	82.0	1627.0
12	52.0	18.0	1573.0	75.0
13	185.0	29.0	1132.0	372.0
14	217.0	918.0	367.0	216.0
15	372.0	129.0	1074.0	143.0
16	201.0	15.0	675.0	827.0
17	120.0	2.0	1467.0	129.0
18	9.0	2.0	1697.0	10.0
19	6.0	5.0	1698.0	9.0
20	44.0	1236.0	360.0	78.0
21	20.0	314.0	1362.0	22.0
22	7.0	43.0	475.0	1193.0
23	89.0	33.0	1179.0	417.0
24	179.5	87.5	1094.5	356.5
25	191.0	526.0	628.0	373.0

PFM

	A	C	G	T
01	0.243	0.182	0.374	0.201
02	0.268	0.113	0.411	0.208
03	0.276	0.176	0.329	0.219
04	0.185	0.034	0.71	0.072
05	0.109	0.006	0.46	0.424
06	0.056	0.001	0.943	0.001
07	0.0	0.0	1.0	0.0
08	0.001	0.0	0.999	0.0
09	0.015	0.965	0.0	0.02
10	0.003	0.0	0.995	0.001
11	0.004	0.001	0.048	0.947
12	0.03	0.01	0.916	0.044
13	0.108	0.017	0.659	0.217
14	0.126	0.534	0.214	0.126
15	0.217	0.075	0.625	0.083
16	0.117	0.009	0.393	0.481
17	0.07	0.001	0.854	0.075
18	0.005	0.001	0.988	0.006
19	0.003	0.003	0.988	0.005
20	0.026	0.719	0.21	0.045
21	0.012	0.183	0.793	0.013
22	0.004	0.025	0.276	0.694
23	0.052	0.019	0.686	0.243
24	0.104	0.051	0.637	0.208
25	0.111	0.306	0.366	0.217

PWM

	A	C	G	T
01	-0.029	-0.315	0.401	-0.215
02	0.069	-0.787	0.495	-0.183
03	0.098	-0.35	0.273	-0.13
04	-0.299	-1.975	1.04	-1.24
05	-0.821	-3.594	0.609	0.527
06	-1.483	-5.015	1.324	-5.015
07	-5.445	-5.445	1.383	-5.445
08	-5.015	-5.445	1.382	-5.445
09	-2.74	1.348	-5.445	-2.487
10	-4.005	-5.445	1.378	-4.716
11	-3.885	-4.716	-1.638	1.329
12	-2.081	-3.078	1.295	-1.725
13	-0.837	-2.637	0.966	-0.143
14	-0.679	0.757	-0.157	-0.683
15	-0.143	-1.193	0.914	-1.091
16	-0.754	-3.242	0.451	0.653
17	-1.264	-4.716	1.225	-1.193
18	-3.682	-4.716	1.371	-3.594
19	-4.005	-4.141	1.371	-3.682
20	-2.241	1.054	-0.176	-1.687
21	-2.982	-0.312	1.151	-2.895
22	-3.885	-2.263	0.1	1.019
23	-1.558	-2.516	1.007	-0.029
24	-0.866	-1.574	0.933	-0.185
25	-0.805	0.202	0.379	-0.14

Standard thresholds

P-value	Threshold
0.001	-4.72749
0.0005	-2.86944
0.0001	1.07316