MotifMEF2B.H13RSNP.1.SM.B
Gene (human)MEF2B
(GeneCards)
Gene synonyms (human)XMEF2
Gene (mouse)Mef2b
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length20
ConsensusnhGWTWCCWWAThbGKhhnn
GC content43.85%
Information content (bits; total / per base)13.838 / 0.692
Data sourcesHT-SELEX + Methyl-HT-SELEX
Aligned words9927
Previous namesMEF2B.H12RSNP.1.SM.B

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 16 (100) 0.697 0.763 0.533 0.615 0.612 0.683 1.541 1.858 53.086 153.678

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 3 experiments median 0.977 0.97 0.897 0.883 0.769 0.77
best 0.999 0.998 0.987 0.984 0.914 0.911
Methyl HT-SELEX, 1 experiments median 0.999 0.998 0.987 0.984 0.914 0.911
best 0.999 0.998 0.987 0.984 0.914 0.911
Non-Methyl HT-SELEX, 2 experiments median 0.751 0.749 0.701 0.697 0.633 0.637
best 0.977 0.97 0.897 0.883 0.769 0.77

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 1.954 2.122 0.106 0.081

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.774 0.347 0.439 0.251
batch 2 0.791 0.361 0.578 0.444
TF superclassalpha-Helices exposed by beta-structures {5} (TFClass)
TF classMADS box factors {5.1} (TFClass)
TF familyRegulators of differentiation {5.1.1} (TFClass)
TF subfamilyMEF2 {5.1.1.1} (TFClass)
TFClass IDTFClass: 5.1.1.1.2
HGNCHGNC:6995
MGIMGI:104526
EntrezGene (human)GeneID:100271849
(SSTAR profile)
GeneID:4207
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)MEF2B_HUMAN
UniProt ID (mouse)MEF2B_MOUSE
UniProt AC (human)Q02080
(TFClass)
UniProt AC (mouse)O55087
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 16 human, 0 mouse
HT-SELEX 2
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
012536.252106.253211.252073.25
021037.253938.25921.254030.25
03470.0760.08346.0351.0
041112.0534.0916.07365.0
05678.0278.0321.08650.0
066483.0319.01228.01897.0
0738.09839.033.017.0
088.09356.063.0500.0
096598.01004.0705.01620.0
103461.0501.0573.05392.0
118170.046.065.01646.0
122032.0262.077.07556.0
132983.01575.01098.04271.0
141247.01521.02703.04456.0
151682.094.07983.0168.0
16505.0298.07703.01421.0
173531.03303.01275.01818.0
184132.02047.01539.02209.0
192600.753403.751499.752422.75
202231.03698.01914.02084.0
PFM
ACGT
010.2550.2120.3230.209
020.1040.3970.0930.406
030.0470.0770.8410.035
040.1120.0540.0920.742
050.0680.0280.0320.871
060.6530.0320.1240.191
070.0040.9910.0030.002
080.0010.9420.0060.05
090.6650.1010.0710.163
100.3490.050.0580.543
110.8230.0050.0070.166
120.2050.0260.0080.761
130.30.1590.1110.43
140.1260.1530.2720.449
150.1690.0090.8040.017
160.0510.030.7760.143
170.3560.3330.1280.183
180.4160.2060.1550.223
190.2620.3430.1510.244
200.2250.3730.1930.21
PWM
ACGT
010.022-0.1640.257-0.18
02-0.8710.461-0.9890.485
03-1.66-1.1811.212-1.95
04-0.802-1.533-0.9951.087
05-1.295-2.182-2.0391.248
060.96-2.045-0.703-0.268
07-4.1211.377-4.254-4.858
08-5.4851.326-3.639-1.598
090.977-0.904-1.256-0.426
100.332-1.596-1.4630.775
111.191-3.94-3.608-0.41
12-0.2-2.241-3.4441.113
130.184-0.454-0.8140.542
14-0.687-0.4890.0850.585
15-0.389-3.251.168-2.68
16-1.589-2.1131.132-0.557
170.3520.286-0.665-0.311
180.509-0.192-0.477-0.116
190.0470.316-0.503-0.024
20-0.1060.399-0.259-0.174
Standard thresholds
P-value Threshold
0.001 3.53356
0.0005 4.61061
0.0001 6.83411