MGA.H13CORE.0.PSG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MGA.H13CORE.0.PSG.A
Gene (human)	MGA (GeneCards)
Gene synonyms (human)	KIAA0518, MAD5
Gene (mouse)	Mga
Gene synonyms (mouse)	Kiaa4252
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	19
Consensus	dAGGTGTGAAWWWTMRCAC
GC content	42.64%
Information content (bits; total / per base)	24.422 / 1.285
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words	8919
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	1 (1)	0.576	0.576	0.442	0.442	0.589	0.589	17.854	17.854

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Lysate, 2 experiments	median	1.0	1.0	1.0	1.0	1.0	1.0
Lysate, 2 experiments	best	1.0	1.0	1.0	1.0	1.0	1.0

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
Lysate, 2 experiments	median	391.339	0.917	0.952	0.931
Lysate, 2 experiments	best	776.215	0.943	0.962	0.943

TF superclass	Basic domains {1} (TFClass)
TF class	Basic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF family	bHLH-ZIP {1.2.6} (TFClass)
TF subfamily	MAD {1.2.6.7} (TFClass)
TFClass ID	TFClass: 1.2.6.7.4
HGNC	HGNC:14010
MGI	MGI:1352483
EntrezGene (human)	GeneID:23269 (SSTAR profile)
EntrezGene (mouse)	GeneID:29808 (SSTAR profile)
UniProt ID (human)	MGAP_HUMAN
UniProt ID (mouse)	MGAP_MOUSE
UniProt AC (human)	Q8IWI9 (TFClass)
UniProt AC (mouse)	A2AWL7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2 overall: 2 Lysate, 0 IVT, 0 GFPIVT
Genomic HT-SELEX	2 overall: 2 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	MGA.H13CORE.0.PSG.A.pcm
PWM	MGA.H13CORE.0.PSG.A.pwm
PFM	MGA.H13CORE.0.PSG.A.pfm
Threshold to P-value map	MGA.H13CORE.0.PSG.A.thr
Motif in other formats
JASPAR format	MGA.H13CORE.0.PSG.A_jaspar_format.txt
MEME format	MGA.H13CORE.0.PSG.A_meme_format.meme
Transfac format	MGA.H13CORE.0.PSG.A_transfac_format.txt
Homer format	MGA.H13CORE.0.PSG.A_homer_format_0.001.txt MGA.H13CORE.0.PSG.A_homer_format_0.0005.txt MGA.H13CORE.0.PSG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	3904.5	704.5	2336.5	1973.5
02	7858.75	86.75	734.75	238.75
03	332.0	318.0	8205.0	64.0
04	0.0	11.0	8905.0	3.0
05	2.0	461.0	2.0	8454.0
06	0.0	0.0	8919.0	0.0
07	97.0	610.0	3.0	8209.0
08	19.0	69.0	8504.0	327.0
09	8856.0	3.0	47.0	13.0
10	7244.0	272.0	409.0	994.0
11	6276.0	231.0	326.0	2086.0
12	2938.0	306.0	361.0	5314.0
13	1600.0	755.0	702.0	5862.0
14	222.0	544.0	151.0	8002.0
15	1295.0	6510.0	859.0	255.0
16	6633.0	168.0	1443.0	675.0
17	29.0	8805.0	23.0	62.0
18	6872.25	109.25	1830.25	107.25
19	212.25	8056.25	480.25	170.25

PFM

	A	C	G	T
01	0.438	0.079	0.262	0.221
02	0.881	0.01	0.082	0.027
03	0.037	0.036	0.92	0.007
04	0.0	0.001	0.998	0.0
05	0.0	0.052	0.0	0.948
06	0.0	0.0	1.0	0.0
07	0.011	0.068	0.0	0.92
08	0.002	0.008	0.953	0.037
09	0.993	0.0	0.005	0.001
10	0.812	0.03	0.046	0.111
11	0.704	0.026	0.037	0.234
12	0.329	0.034	0.04	0.596
13	0.179	0.085	0.079	0.657
14	0.025	0.061	0.017	0.897
15	0.145	0.73	0.096	0.029
16	0.744	0.019	0.162	0.076
17	0.003	0.987	0.003	0.007
18	0.771	0.012	0.205	0.012
19	0.024	0.903	0.054	0.019

PWM

	A	C	G	T
01	0.56	-1.15	0.047	-0.122
02	1.259	-3.222	-1.108	-2.226
03	-1.899	-1.941	1.302	-3.517
04	-6.889	-5.125	1.384	-6.048
05	-6.258	-1.572	-6.258	1.332
06	-6.889	-6.889	1.386	-6.889
07	-3.113	-1.293	-6.048	1.303
08	-4.653	-3.444	1.338	-1.914
09	1.378	-6.048	-3.813	-4.985
10	1.178	-2.097	-1.691	-0.807
11	1.034	-2.258	-1.917	-0.067
12	0.276	-1.98	-1.816	0.868
13	-0.331	-1.081	-1.153	0.966
14	-2.298	-1.408	-2.678	1.277
15	-0.543	1.071	-0.952	-2.161
16	1.089	-2.573	-0.435	-1.193
17	-4.268	1.373	-4.481	-3.548
18	1.125	-2.996	-0.197	-3.015
19	-2.342	1.284	-1.532	-2.56

Standard thresholds

P-value	Threshold
0.001	-4.06089
0.0005	-2.20509
0.0001	1.70041