| Motif | NFIB.H13RSNP.0.PSM.A |
| Gene (human) | NFIB (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfib |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | NFIB.H13RSNP.0.PSM.A |
| Gene (human) | NFIB (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Nfib |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 20 |
| Consensus | nnTTGGCAhCdTGCCAAvnn |
| GC content | 54.1% |
| Information content (bits; total / per base) | 23.615 / 1.181 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 412 |
| Previous names | NFIB.H12RSNP.0.PSM.A |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 2 (14) | 0.823 | 0.881 | 0.824 | 0.885 | 0.961 | 0.996 | 6.668 | 7.308 | 817.806 | 1257.658 |
| Mouse | 4 (28) | 0.554 | 0.696 | 0.453 | 0.673 | 0.756 | 0.943 | 2.561 | 4.898 | 114.903 | 362.721 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.87 | 0.88 | 0.804 | 0.817 | 0.777 | 0.788 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| Methyl HT-SELEX, 1 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.74 | 0.76 | 0.609 | 0.634 | 0.554 | 0.577 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.571 | 0.154 | 0.218 | 0.147 |
| TF superclass | beta-Hairpin exposed by an alpha/beta-scaffold {7} (TFClass) |
| TF class | SMAD/NF-1 DNA-binding domain factors {7.1} (TFClass) |
| TF family | NF-1 {7.1.2} (TFClass) |
| TF subfamily | {7.1.2.0} (TFClass) |
| TFClass ID | TFClass: 7.1.2.0.2 |
| HGNC | HGNC:7785 |
| MGI | MGI:103188 |
| EntrezGene (human) | GeneID:4781 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:18028 (SSTAR profile) |
| UniProt ID (human) | NFIB_HUMAN |
| UniProt ID (mouse) | NFIB_MOUSE |
| UniProt AC (human) | O00712 (TFClass) |
| UniProt AC (mouse) | P97863 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 4 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | NFIB.H13RSNP.0.PSM.A.pcm |
| PWM | NFIB.H13RSNP.0.PSM.A.pwm |
| PFM | NFIB.H13RSNP.0.PSM.A.pfm |
| Threshold to P-value map | NFIB.H13RSNP.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | NFIB.H13RSNP.0.PSM.A_jaspar_format.txt |
| MEME format | NFIB.H13RSNP.0.PSM.A_meme_format.meme |
| Transfac format | NFIB.H13RSNP.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 154.25 | 82.25 | 88.25 | 87.25 |
| 02 | 55.25 | 130.25 | 124.25 | 102.25 |
| 03 | 3.0 | 104.0 | 2.0 | 303.0 |
| 04 | 0.0 | 0.0 | 0.0 | 412.0 |
| 05 | 0.0 | 0.0 | 412.0 | 0.0 |
| 06 | 0.0 | 1.0 | 411.0 | 0.0 |
| 07 | 0.0 | 412.0 | 0.0 | 0.0 |
| 08 | 393.0 | 0.0 | 6.0 | 13.0 |
| 09 | 117.0 | 145.0 | 41.0 | 109.0 |
| 10 | 190.0 | 222.0 | 0.0 | 0.0 |
| 11 | 58.0 | 41.0 | 243.0 | 70.0 |
| 12 | 2.0 | 0.0 | 0.0 | 410.0 |
| 13 | 0.0 | 0.0 | 412.0 | 0.0 |
| 14 | 0.0 | 412.0 | 0.0 | 0.0 |
| 15 | 0.0 | 412.0 | 0.0 | 0.0 |
| 16 | 412.0 | 0.0 | 0.0 | 0.0 |
| 17 | 309.0 | 6.0 | 97.0 | 0.0 |
| 18 | 81.0 | 159.0 | 107.0 | 65.0 |
| 19 | 85.25 | 117.25 | 66.25 | 143.25 |
| 20 | 101.5 | 132.5 | 71.5 | 106.5 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.374 | 0.2 | 0.214 | 0.212 |
| 02 | 0.134 | 0.316 | 0.302 | 0.248 |
| 03 | 0.007 | 0.252 | 0.005 | 0.735 |
| 04 | 0.0 | 0.0 | 0.0 | 1.0 |
| 05 | 0.0 | 0.0 | 1.0 | 0.0 |
| 06 | 0.0 | 0.002 | 0.998 | 0.0 |
| 07 | 0.0 | 1.0 | 0.0 | 0.0 |
| 08 | 0.954 | 0.0 | 0.015 | 0.032 |
| 09 | 0.284 | 0.352 | 0.1 | 0.265 |
| 10 | 0.461 | 0.539 | 0.0 | 0.0 |
| 11 | 0.141 | 0.1 | 0.59 | 0.17 |
| 12 | 0.005 | 0.0 | 0.0 | 0.995 |
| 13 | 0.0 | 0.0 | 1.0 | 0.0 |
| 14 | 0.0 | 1.0 | 0.0 | 0.0 |
| 15 | 0.0 | 1.0 | 0.0 | 0.0 |
| 16 | 1.0 | 0.0 | 0.0 | 0.0 |
| 17 | 0.75 | 0.015 | 0.235 | 0.0 |
| 18 | 0.197 | 0.386 | 0.26 | 0.158 |
| 19 | 0.207 | 0.285 | 0.161 | 0.348 |
| 20 | 0.246 | 0.322 | 0.174 | 0.258 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.399 | -0.221 | -0.152 | -0.163 |
| 02 | -0.61 | 0.232 | 0.185 | -0.007 |
| 03 | -3.144 | 0.01 | -3.395 | 1.069 |
| 04 | -4.24 | -4.24 | -4.24 | 1.375 |
| 05 | -4.24 | -4.24 | 1.375 | -4.24 |
| 06 | -4.24 | -3.731 | 1.373 | -4.24 |
| 07 | -4.24 | 1.375 | -4.24 | -4.24 |
| 08 | 1.328 | -4.24 | -2.634 | -1.975 |
| 09 | 0.126 | 0.338 | -0.9 | 0.056 |
| 10 | 0.606 | 0.76 | -4.24 | -4.24 |
| 11 | -0.563 | -0.9 | 0.85 | -0.379 |
| 12 | -3.395 | -4.24 | -4.24 | 1.371 |
| 13 | -4.24 | -4.24 | 1.375 | -4.24 |
| 14 | -4.24 | 1.375 | -4.24 | -4.24 |
| 15 | -4.24 | 1.375 | -4.24 | -4.24 |
| 16 | 1.375 | -4.24 | -4.24 | -4.24 |
| 17 | 1.089 | -2.634 | -0.059 | -4.24 |
| 18 | -0.236 | 0.429 | 0.038 | -0.452 |
| 19 | -0.186 | 0.128 | -0.433 | 0.326 |
| 20 | -0.014 | 0.249 | -0.359 | 0.033 |
| P-value | Threshold |
|---|---|
| 0.001 | -4.20834 |
| 0.0005 | -2.14409 |
| 0.0001 | 1.50931 |