MotifNR2C1.H13RSNP.1.PM.A
Gene (human)NR2C1
(GeneCards)
Gene synonyms (human)TR2
Gene (mouse)Nr2c1
Gene synonyms (mouse)Tr2, Tr2-11
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length19
ConsensusndRGGTYAAAGGTCAhdvb
GC content52.29%
Information content (bits; total / per base)19.039 / 1.002
Data sourcesChIP-Seq + Methyl-HT-SELEX
Aligned words562
Previous namesNR2C1.H12RSNP.1.PM.A

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 3 (21) 0.709 0.792 0.632 0.749 0.692 0.793 3.094 4.31 77.097 165.699

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.971 0.959 0.931 0.911 0.864 0.842
best 0.993 0.991 0.97 0.961 0.914 0.899
Methyl HT-SELEX, 1 experiments median 0.993 0.991 0.97 0.961 0.914 0.899
best 0.993 0.991 0.97 0.961 0.914 0.899
Non-Methyl HT-SELEX, 1 experiments median 0.949 0.928 0.892 0.861 0.814 0.785
best 0.949 0.928 0.892 0.861 0.814 0.785

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 6.879 6.415 0.234 0.084

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.611 0.075 0.5 0.29
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classNuclear receptors with C4 zinc fingers {2.1} (TFClass)
TF familyRXR-related receptors {2.1.3} (TFClass)
TF subfamilyTR (NR2C) {2.1.3.4} (TFClass)
TFClass IDTFClass: 2.1.3.4.1
HGNCHGNC:7971
MGIMGI:1352465
EntrezGene (human)GeneID:7181
(SSTAR profile)
EntrezGene (mouse)GeneID:22025
(SSTAR profile)
UniProt ID (human)NR2C1_HUMAN
UniProt ID (mouse)NR2C1_MOUSE
UniProt AC (human)P13056
(TFClass)
UniProt AC (mouse)Q505F1
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 3 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01177.581.5145.5157.5
02214.041.0232.075.0
03285.012.0250.015.0
048.018.0524.012.0
053.018.0500.041.0
066.030.045.0481.0
0716.0449.044.053.0
08486.013.050.013.0
09466.05.044.047.0
10521.01.040.00.0
111.01.0560.00.0
120.00.0562.00.0
130.02.016.0544.0
143.0488.014.057.0
15430.04.0126.02.0
16157.099.087.0219.0
17132.075.0268.087.0
18103.2582.25301.2575.25
1997.25121.25233.25110.25
PFM
ACGT
010.3160.1450.2590.28
020.3810.0730.4130.133
030.5070.0210.4450.027
040.0140.0320.9320.021
050.0050.0320.890.073
060.0110.0530.080.856
070.0280.7990.0780.094
080.8650.0230.0890.023
090.8290.0090.0780.084
100.9270.0020.0710.0
110.0020.0020.9960.0
120.00.01.00.0
130.00.0040.0280.968
140.0050.8680.0250.101
150.7650.0070.2240.004
160.2790.1760.1550.39
170.2350.1330.4770.155
180.1840.1460.5360.134
190.1730.2160.4150.196
PWM
ACGT
010.231-0.5370.0350.113
020.417-1.2050.497-0.618
030.702-2.3480.571-2.148
04-2.696-1.9821.308-2.348
05-3.434-1.9821.261-1.205
06-2.931-1.504-1.1151.223
07-2.0891.154-1.137-0.957
081.233-2.277-1.013-2.277
091.191-3.072-1.137-1.073
101.302-4.008-1.229-4.497
11-4.008-4.0081.374-4.497
12-4.497-4.4971.378-4.497
13-4.497-3.68-2.0891.345
14-3.4341.237-2.21-0.886
151.111-3.237-0.108-3.68
160.11-0.345-0.4720.44
17-0.062-0.6180.64-0.472
18-0.304-0.5280.757-0.615
19-0.363-0.1460.502-0.239
Standard thresholds
P-value Threshold
0.001 0.99281
0.0005 2.37641
0.0001 5.28491