| Motif | PRDM5.H13INVIVO.0.PSGI.A |
| Gene (human) | PRDM5 (GeneCards) |
| Gene synonyms (human) | PFM2 |
| Gene (mouse) | Prdm5 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | PRDM5.H13INVIVO.0.PSGI.A |
| Gene (human) | PRDM5 (GeneCards) |
| Gene synonyms (human) | PFM2 |
| Gene (mouse) | Prdm5 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 15 |
| Consensus | vMCYbRhYCWCCdbb |
| GC content | 65.38% |
| Information content (bits; total / per base) | 11.833 / 0.789 |
| Data sources | ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq |
| Aligned words | 1000 |
| Previous names |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|
| Overall | 2 (3) | 0.816 | 0.838 | 0.685 | 0.71 | 0.824 | 0.851 | 184.481 | 230.036 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| overall, 4 experiments | median | 0.958 | 0.942 | 0.902 | 0.886 | 0.822 | 0.82 |
| best | 0.994 | 0.991 | 0.99 | 0.983 | 0.976 | 0.967 | |
| Lysate, 2 experiments | median | 0.899 | 0.867 | 0.788 | 0.764 | 0.663 | 0.669 |
| best | 0.923 | 0.895 | 0.819 | 0.795 | 0.681 | 0.69 | |
| GFPIVT, 2 experiments | median | 0.994 | 0.99 | 0.988 | 0.98 | 0.97 | 0.958 |
| best | 0.994 | 0.991 | 0.99 | 0.983 | 0.976 | 0.967 | |
| Genomic HT-SELEX benchmarking | Centrality | pseudo-auROC | auROC | auPR | |
|---|---|---|---|---|---|
| overall, 4 experiments | median | 227.433 | 0.843 | 0.835 | 0.695 |
| best | 402.432 | 0.871 | 0.848 | 0.738 | |
| Lysate, 2 experiments | median | 212.965 | 0.796 | 0.773 | 0.631 |
| best | 274.509 | 0.838 | 0.829 | 0.686 | |
| GFPIVT, 2 experiments | median | 238.878 | 0.85 | 0.839 | 0.71 |
| best | 402.432 | 0.871 | 0.848 | 0.738 | |
| SMiLE-Seq benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.833 | 0.803 | 0.718 | 0.708 | 0.63 | 0.637 |
| best | 0.934 | 0.9 | 0.838 | 0.809 | 0.723 | 0.715 | |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | More than 3 adjacent zinc fingers {2.3.3} (TFClass) |
| TF subfamily | Unclassified {2.3.3.0} (TFClass) |
| TFClass ID | TFClass: 2.3.3.0.195 |
| HGNC | HGNC:9349 |
| MGI | MGI:1918029 |
| EntrezGene (human) | GeneID:11107 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:70779 (SSTAR profile) |
| UniProt ID (human) | PRDM5_HUMAN |
| UniProt ID (mouse) | PRDM5_MOUSE |
| UniProt AC (human) | Q9NQX1 (TFClass) |
| UniProt AC (mouse) | Q9CXE0 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 0 mouse |
| HT-SELEX | 4 overall: 2 Lysate, 0 IVT, 2 GFPIVT |
| Genomic HT-SELEX | 4 overall: 2 Lysate, 0 IVT, 2 GFPIVT |
| SMiLE-Seq | 2 |
| PBM | 0 |
| PCM | PRDM5.H13INVIVO.0.PSGI.A.pcm |
| PWM | PRDM5.H13INVIVO.0.PSGI.A.pwm |
| PFM | PRDM5.H13INVIVO.0.PSGI.A.pfm |
| Threshold to P-value map | PRDM5.H13INVIVO.0.PSGI.A.thr |
| Motif in other formats | |
| JASPAR format | PRDM5.H13INVIVO.0.PSGI.A_jaspar_format.txt |
| MEME format | PRDM5.H13INVIVO.0.PSGI.A_meme_format.meme |
| Transfac format | PRDM5.H13INVIVO.0.PSGI.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 486.0 | 175.0 | 211.0 | 128.0 |
| 02 | 256.0 | 682.0 | 52.0 | 10.0 |
| 03 | 5.0 | 985.0 | 0.0 | 10.0 |
| 04 | 107.0 | 570.0 | 44.0 | 279.0 |
| 05 | 34.0 | 261.0 | 284.0 | 421.0 |
| 06 | 144.0 | 86.0 | 695.0 | 75.0 |
| 07 | 366.0 | 303.0 | 149.0 | 182.0 |
| 08 | 15.0 | 379.0 | 161.0 | 445.0 |
| 09 | 17.0 | 929.0 | 1.0 | 53.0 |
| 10 | 180.0 | 98.0 | 8.0 | 714.0 |
| 11 | 1.0 | 998.0 | 1.0 | 0.0 |
| 12 | 2.0 | 997.0 | 1.0 | 0.0 |
| 13 | 396.0 | 138.0 | 265.0 | 201.0 |
| 14 | 11.0 | 303.0 | 361.0 | 325.0 |
| 15 | 69.0 | 414.0 | 256.0 | 261.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.486 | 0.175 | 0.211 | 0.128 |
| 02 | 0.256 | 0.682 | 0.052 | 0.01 |
| 03 | 0.005 | 0.985 | 0.0 | 0.01 |
| 04 | 0.107 | 0.57 | 0.044 | 0.279 |
| 05 | 0.034 | 0.261 | 0.284 | 0.421 |
| 06 | 0.144 | 0.086 | 0.695 | 0.075 |
| 07 | 0.366 | 0.303 | 0.149 | 0.182 |
| 08 | 0.015 | 0.379 | 0.161 | 0.445 |
| 09 | 0.017 | 0.929 | 0.001 | 0.053 |
| 10 | 0.18 | 0.098 | 0.008 | 0.714 |
| 11 | 0.001 | 0.998 | 0.001 | 0.0 |
| 12 | 0.002 | 0.997 | 0.001 | 0.0 |
| 13 | 0.396 | 0.138 | 0.265 | 0.201 |
| 14 | 0.011 | 0.303 | 0.361 | 0.325 |
| 15 | 0.069 | 0.414 | 0.256 | 0.261 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.661 | -0.354 | -0.168 | -0.663 |
| 02 | 0.024 | 0.999 | -1.544 | -3.066 |
| 03 | -3.622 | 1.366 | -4.982 | -3.066 |
| 04 | -0.84 | 0.82 | -1.706 | 0.109 |
| 05 | -1.952 | 0.043 | 0.127 | 0.518 |
| 06 | -0.547 | -1.054 | 1.018 | -1.188 |
| 07 | 0.379 | 0.191 | -0.513 | -0.315 |
| 08 | -2.711 | 0.414 | -0.436 | 0.574 |
| 09 | -2.598 | 1.308 | -4.525 | -1.526 |
| 10 | -0.326 | -0.926 | -3.253 | 1.045 |
| 11 | -4.525 | 1.379 | -4.525 | -4.982 |
| 12 | -4.213 | 1.378 | -4.525 | -4.982 |
| 13 | 0.457 | -0.589 | 0.058 | -0.216 |
| 14 | -2.985 | 0.191 | 0.365 | 0.261 |
| 15 | -1.27 | 0.502 | 0.024 | 0.043 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.15186 |
| 0.0005 | 5.26901 |
| 0.0001 | 7.40201 |