| Motif | SRF.H13RSNP.0.PSM.A |
| Gene (human) | SRF (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Srf |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | SRF.H13RSNP.0.PSM.A |
| Gene (human) | SRF (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Srf |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 17 |
| Consensus | dYKbCCTTWTWTGGbhW |
| GC content | 39.55% |
| Information content (bits; total / per base) | 15.127 / 0.89 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 307 |
| Previous names | SRF.H12RSNP.0.PSM.A |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 21 (147) | 0.797 | 0.97 | 0.795 | 0.948 | 0.782 | 0.967 | 3.897 | 5.403 | 421.678 | 891.032 |
| Mouse | 19 (113) | 0.907 | 0.979 | 0.888 | 0.967 | 0.897 | 0.978 | 5.228 | 7.679 | 261.538 | 683.569 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 5 experiments | median | 0.664 | 0.692 | 0.564 | 0.592 | 0.526 | 0.55 |
| best | 0.983 | 0.97 | 0.97 | 0.954 | 0.919 | 0.901 | |
| Methyl HT-SELEX, 1 experiments | median | 0.983 | 0.97 | 0.97 | 0.954 | 0.919 | 0.901 |
| best | 0.983 | 0.97 | 0.97 | 0.954 | 0.919 | 0.901 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.624 | 0.646 | 0.553 | 0.57 | 0.523 | 0.539 |
| best | 0.975 | 0.955 | 0.958 | 0.934 | 0.904 | 0.88 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 4.842 | 5.636 | 0.427 | 0.243 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.876 | 0.128 | 0.795 | 0.295 |
| TF superclass | alpha-Helices exposed by beta-structures {5} (TFClass) |
| TF class | MADS box factors {5.1} (TFClass) |
| TF family | Responders to external signals {5.1.2} (TFClass) |
| TF subfamily | {5.1.2.0} (TFClass) |
| TFClass ID | TFClass: 5.1.2.0.1 |
| HGNC | HGNC:11291 |
| MGI | MGI:106658 |
| EntrezGene (human) | GeneID:6722 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:20807 (SSTAR profile) |
| UniProt ID (human) | SRF_HUMAN |
| UniProt ID (mouse) | SRF_MOUSE |
| UniProt AC (human) | P11831 (TFClass) |
| UniProt AC (mouse) | Q9JM73 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 21 human, 19 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 1 |
| Genomic HT-SELEX | 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT |
| SMiLE-Seq | 0 |
| PBM | 0 |
| PCM | SRF.H13RSNP.0.PSM.A.pcm |
| PWM | SRF.H13RSNP.0.PSM.A.pwm |
| PFM | SRF.H13RSNP.0.PSM.A.pfm |
| Threshold to P-value map | SRF.H13RSNP.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | SRF.H13RSNP.0.PSM.A_jaspar_format.txt |
| MEME format | SRF.H13RSNP.0.PSM.A_meme_format.meme |
| Transfac format | SRF.H13RSNP.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 133.0 | 54.0 | 63.0 | 57.0 |
| 02 | 27.0 | 56.0 | 26.0 | 198.0 |
| 03 | 21.0 | 27.0 | 66.0 | 193.0 |
| 04 | 30.0 | 85.0 | 83.0 | 109.0 |
| 05 | 5.0 | 287.0 | 5.0 | 10.0 |
| 06 | 3.0 | 272.0 | 0.0 | 32.0 |
| 07 | 78.0 | 5.0 | 2.0 | 222.0 |
| 08 | 28.0 | 1.0 | 3.0 | 275.0 |
| 09 | 213.0 | 6.0 | 10.0 | 78.0 |
| 10 | 16.0 | 6.0 | 0.0 | 285.0 |
| 11 | 133.0 | 5.0 | 5.0 | 164.0 |
| 12 | 41.0 | 4.0 | 12.0 | 250.0 |
| 13 | 21.0 | 4.0 | 277.0 | 5.0 |
| 14 | 6.0 | 2.0 | 285.0 | 14.0 |
| 15 | 43.0 | 139.0 | 67.0 | 58.0 |
| 16 | 95.0 | 147.0 | 15.0 | 50.0 |
| 17 | 196.0 | 10.0 | 35.0 | 66.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.433 | 0.176 | 0.205 | 0.186 |
| 02 | 0.088 | 0.182 | 0.085 | 0.645 |
| 03 | 0.068 | 0.088 | 0.215 | 0.629 |
| 04 | 0.098 | 0.277 | 0.27 | 0.355 |
| 05 | 0.016 | 0.935 | 0.016 | 0.033 |
| 06 | 0.01 | 0.886 | 0.0 | 0.104 |
| 07 | 0.254 | 0.016 | 0.007 | 0.723 |
| 08 | 0.091 | 0.003 | 0.01 | 0.896 |
| 09 | 0.694 | 0.02 | 0.033 | 0.254 |
| 10 | 0.052 | 0.02 | 0.0 | 0.928 |
| 11 | 0.433 | 0.016 | 0.016 | 0.534 |
| 12 | 0.134 | 0.013 | 0.039 | 0.814 |
| 13 | 0.068 | 0.013 | 0.902 | 0.016 |
| 14 | 0.02 | 0.007 | 0.928 | 0.046 |
| 15 | 0.14 | 0.453 | 0.218 | 0.189 |
| 16 | 0.309 | 0.479 | 0.049 | 0.163 |
| 17 | 0.638 | 0.033 | 0.114 | 0.215 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.542 | -0.344 | -0.193 | -0.291 |
| 02 | -1.012 | -0.308 | -1.047 | 0.936 |
| 03 | -1.249 | -1.012 | -0.148 | 0.911 |
| 04 | -0.911 | 0.1 | 0.077 | 0.345 |
| 05 | -2.498 | 1.305 | -2.498 | -1.923 |
| 06 | -2.87 | 1.252 | -4.0 | -0.85 |
| 07 | 0.016 | -2.498 | -3.126 | 1.05 |
| 08 | -0.977 | -3.47 | -2.87 | 1.263 |
| 09 | 1.009 | -2.353 | -1.923 | 0.016 |
| 10 | -1.501 | -2.353 | -4.0 | 1.298 |
| 11 | 0.542 | -2.498 | -2.498 | 0.75 |
| 12 | -0.611 | -2.667 | -1.761 | 1.168 |
| 13 | -1.249 | -2.667 | 1.27 | -2.498 |
| 14 | -2.353 | -3.126 | 1.298 | -1.623 |
| 15 | -0.565 | 0.586 | -0.133 | -0.274 |
| 16 | 0.21 | 0.641 | -1.56 | -0.419 |
| 17 | 0.926 | -1.923 | -0.764 | -0.148 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.29491 |
| 0.0005 | 4.38036 |
| 0.0001 | 6.65796 |