MotifTBX3.H13RSNP.0.PSM.A
Gene (human)TBX3
(GeneCards)
Gene synonyms (human)
Gene (mouse)Tbx3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length14
ConsensusdddAGGTGTKAddd
GC content49.74%
Information content (bits; total / per base)15.665 / 1.119
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words5717
Previous namesTBX3.H12RSNP.0.PSM.A

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.637 0.648 0.506 0.514 0.66 0.681 1.77 1.878 41.004 45.824
Mouse 3 (17) 0.664 0.674 0.476 0.543 0.614 0.654 1.452 1.696 6.187 28.114

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.967 0.946 0.944 0.918 0.892 0.864
best 0.985 0.974 0.97 0.955 0.926 0.906
Methyl HT-SELEX, 1 experiments median 0.985 0.974 0.97 0.955 0.926 0.906
best 0.985 0.974 0.97 0.955 0.926 0.906
Non-Methyl HT-SELEX, 1 experiments median 0.949 0.919 0.917 0.881 0.858 0.822
best 0.949 0.919 0.917 0.881 0.858 0.822

rSNP benchmarking, ADASTRA odds-ratio -log-Fisher's P Pearson r Kendall tau
# 12.327 2.788 0.056 0.026

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.968 0.527 0.905 0.649
batch 2 0.817 0.659 0.832 0.595
TF superclassImmunoglobulin fold {6} (TFClass)
TF classT-Box factors {6.5} (TFClass)
TF familyTBX2-related {6.5.4} (TFClass)
TF subfamily {6.5.4.0} (TFClass)
TFClass IDTFClass: 6.5.4.0.2
HGNCHGNC:11602
MGIMGI:98495
EntrezGene (human)GeneID:6926
(SSTAR profile)
EntrezGene (mouse)GeneID:21386
(SSTAR profile)
UniProt ID (human)TBX3_HUMAN
UniProt ID (mouse)TBX3_MOUSE
UniProt AC (human)O15119
(TFClass)
UniProt AC (mouse)P70324
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 3 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
011025.0871.02360.01461.0
02904.75807.752228.751775.75
032033.0190.02450.01044.0
045663.00.054.00.0
050.00.05717.00.0
060.00.05717.00.0
070.0174.00.05543.0
080.00.05717.00.0
091.076.00.05640.0
105.0449.04155.01108.0
115659.00.058.00.0
122663.0460.01594.01000.0
131133.75680.753164.75737.75
141092.0844.02043.01738.0
PFM
ACGT
010.1790.1520.4130.256
020.1580.1410.390.311
030.3560.0330.4290.183
040.9910.00.0090.0
050.00.01.00.0
060.00.01.00.0
070.00.030.00.97
080.00.01.00.0
090.00.0130.00.987
100.0010.0790.7270.194
110.990.00.010.0
120.4660.080.2790.175
130.1980.1190.5540.129
140.1910.1480.3570.304
PWM
ACGT
01-0.332-0.4940.5010.022
02-0.456-0.5690.4440.217
030.352-2.0080.538-0.314
041.376-6.495-3.238-6.495
05-6.495-6.4951.385-6.495
06-6.495-6.4951.385-6.495
07-6.495-2.095-6.4951.354
08-6.495-6.4951.385-6.495
09-6.115-2.908-6.4951.372
10-5.298-1.1551.066-0.254
111.375-6.495-3.169-6.495
120.622-1.130.109-0.357
13-0.231-0.740.794-0.66
14-0.269-0.5260.3570.195
Standard thresholds
P-value Threshold
0.001 -0.05719
0.0005 1.75061
0.0001 5.351215