MotifTFE3.H13RSNP.0.PSM.A
Gene (human)TFE3
(GeneCards)
Gene synonyms (human)BHLHE33
Gene (mouse)Tfe3
Gene synonyms (mouse)Tcfe3
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length14
ConsensusnndGTCACGTGMbn
GC content51.83%
Information content (bits; total / per base)16.583 / 1.184
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words645
Previous namesTFE3.H12RSNP.0.PSM.A

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (7) 0.579 0.588 0.498 0.511 0.775 0.806 2.647 2.859 221.18 259.252
Mouse 9 (60) 0.959 0.992 0.957 0.992 0.994 0.999 7.618 8.193 645.198 1133.602

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.98 0.972 0.897 0.898 0.818 0.83
best 0.996 0.994 0.994 0.989 0.986 0.979
Methyl HT-SELEX, 1 experiments median 0.996 0.994 0.992 0.988 0.98 0.973
best 0.996 0.994 0.992 0.988 0.98 0.973
Non-Methyl HT-SELEX, 3 experiments median 0.964 0.954 0.802 0.808 0.656 0.687
best 0.995 0.99 0.994 0.989 0.986 0.979

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.983 0.867 0.973 0.601
batch 2 0.687 0.356 0.68 0.456
TF superclassBasic domains {1} (TFClass)
TF classBasic helix-loop-helix factors (bHLH) {1.2} (TFClass)
TF familybHLH-ZIP {1.2.6} (TFClass)
TF subfamilyTFE3 {1.2.6.1} (TFClass)
TFClass IDTFClass: 1.2.6.1.1
HGNCHGNC:11752
MGIMGI:98511
EntrezGene (human)GeneID:7030
(SSTAR profile)
EntrezGene (mouse)GeneID:209446
(SSTAR profile)
UniProt ID (human)TFE3_HUMAN
UniProt ID (mouse)TFE3_MOUSE
UniProt AC (human)P19532
(TFClass)
UniProt AC (mouse)Q64092
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 9 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
Genomic HT-SELEX 0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq 0
PBM 0
PCM
ACGT
01202.0132.0156.0155.0
02212.2586.25179.25167.25
03186.058.0292.0109.0
04175.00.0470.00.0
050.00.00.0645.0
060.0645.00.00.0
07645.00.00.00.0
080.0645.00.00.0
090.00.0645.00.0
100.00.00.0645.0
110.00.0645.00.0
12474.096.071.04.0
1372.2589.25164.25319.25
14167.0132.0174.0172.0
PFM
ACGT
010.3130.2050.2420.24
020.3290.1340.2780.259
030.2880.090.4530.169
040.2710.00.7290.0
050.00.00.01.0
060.01.00.00.0
071.00.00.00.0
080.01.00.00.0
090.00.01.00.0
100.00.00.01.0
110.00.01.00.0
120.7350.1490.110.006
130.1120.1380.2550.495
140.2590.2050.270.267
PWM
ACGT
010.223-0.198-0.033-0.039
020.272-0.6170.1050.036
030.141-1.0050.589-0.387
040.081-4.6121.063-4.612
05-4.612-4.612-4.6121.379
06-4.6121.379-4.612-4.612
071.379-4.612-4.612-4.612
08-4.6121.379-4.612-4.612
09-4.612-4.6121.379-4.612
10-4.612-4.612-4.6121.379
11-4.612-4.6121.379-4.612
121.072-0.512-0.808-3.367
13-0.791-0.5840.0180.678
140.035-0.1980.0750.064
Standard thresholds
P-value Threshold
0.001 -0.11893
0.0005 2.016265
0.0001 5.297595