TIGD3.H13INVIVO.0.PSGIB.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	TIGD3.H13INVIVO.0.PSGIB.A
Gene (human)	TIGD3 (GeneCards)
Gene synonyms (human)
Gene (mouse)	Tigd3
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	15
Consensus	hYATbChSbTAWvvR
GC content	37.05%
Information content (bits; total / per base)	11.323 / 0.755
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM
Aligned words	1000
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	3 (3)	0.884	0.886	0.819	0.822	0.726	0.746	133.469	207.638

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 3 experiments	median	1.0	1.0	1.0	1.0	0.999	0.999
overall, 3 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999
Lysate, 2 experiments	median	1.0	1.0	1.0	1.0	0.999	0.999
Lysate, 2 experiments	best	1.0	1.0	1.0	1.0	0.999	0.999
GFPIVT, 1 experiments	median	0.999	0.999	0.963	0.964	0.736	0.788
GFPIVT, 1 experiments	best	0.999	0.999	0.963	0.964	0.736	0.788

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
Lysate, 2 experiments	median	526.31	0.949	0.94	0.896
Lysate, 2 experiments	best	750.387	0.951	0.958	0.915

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 1 experiments	median	0.825	0.8	0.674	0.677	0.564	0.597
Overall, 1 experiments	best	0.825	0.8	0.674	0.677	0.564	0.597

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 10 experiments	median	0.771	0.054	0.708	0.043
Overall, 10 experiments	best	0.782	0.075	0.817	0.095

TF superclass	Helix-turn-helix domains {3} (TFClass)
TF class	Other {3.0} (TFClass)
TF family	CENPB {3.0.256} (TFClass)
TF subfamily	{3.0.256.0} (TFClass)
TFClass ID	TFClass: 3.0.256.0.2
HGNC
MGI
EntrezGene (human)
EntrezGene (mouse)
UniProt ID (human)	TIGD3_HUMAN
UniProt ID (mouse)	TIGD3_MOUSE
UniProt AC (human)	Q6B0B8 (TFClass)
UniProt AC (mouse)	Q7TM95 (TFClass)
GRECO-DB-TF	no

ChIP-Seq	3 human, 0 mouse
HT-SELEX	3 overall: 2 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	2 overall: 2 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	1
PBM	10

PCM	TIGD3.H13INVIVO.0.PSGIB.A.pcm
PWM	TIGD3.H13INVIVO.0.PSGIB.A.pwm
PFM	TIGD3.H13INVIVO.0.PSGIB.A.pfm
Threshold to P-value map	TIGD3.H13INVIVO.0.PSGIB.A.thr
Motif in other formats
JASPAR format	TIGD3.H13INVIVO.0.PSGIB.A_jaspar_format.txt
MEME format	TIGD3.H13INVIVO.0.PSGIB.A_meme_format.meme
Transfac format	TIGD3.H13INVIVO.0.PSGIB.A_transfac_format.txt
Homer format	TIGD3.H13INVIVO.0.PSGIB.A_homer_format_0.001.txt TIGD3.H13INVIVO.0.PSGIB.A_homer_format_0.0005.txt TIGD3.H13INVIVO.0.PSGIB.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	193.0	221.0	106.0	480.0
02	108.0	146.0	63.0	683.0
03	920.0	2.0	12.0	66.0
04	13.0	9.0	21.0	957.0
05	33.0	197.0	359.0	411.0
06	54.0	886.0	7.0	53.0
07	397.0	400.0	75.0	128.0
08	57.0	502.0	357.0	84.0
09	135.0	148.0	165.0	552.0
10	167.0	18.0	7.0	808.0
11	959.0	13.0	24.0	4.0
12	579.0	51.0	80.0	290.0
13	327.0	295.0	332.0	46.0
14	237.0	552.0	132.0	79.0
15	589.0	51.0	326.0	34.0

PFM

	A	C	G	T
01	0.193	0.221	0.106	0.48
02	0.108	0.146	0.063	0.683
03	0.92	0.002	0.012	0.066
04	0.013	0.009	0.021	0.957
05	0.033	0.197	0.359	0.411
06	0.054	0.886	0.007	0.053
07	0.397	0.4	0.075	0.128
08	0.057	0.502	0.357	0.084
09	0.135	0.148	0.165	0.552
10	0.167	0.018	0.007	0.808
11	0.959	0.013	0.024	0.004
12	0.579	0.051	0.08	0.29
13	0.327	0.295	0.332	0.046
14	0.237	0.552	0.132	0.079
15	0.589	0.051	0.326	0.034

PWM

	A	C	G	T
01	-0.257	-0.122	-0.849	0.649
02	-0.83	-0.533	-1.358	1.001
03	1.298	-4.213	-2.909	-1.313
04	-2.839	-3.156	-2.405	1.337
05	-1.981	-0.236	0.36	0.494
06	-1.508	1.26	-3.362	-1.526
07	0.46	0.467	-1.188	-0.663
08	-1.455	0.694	0.354	-1.077
09	-0.61	-0.52	-0.412	0.788
10	-0.4	-2.546	-3.362	1.168
11	1.339	-2.839	-2.281	-3.783
12	0.836	-1.563	-1.125	0.147
13	0.267	0.164	0.282	-1.663
14	-0.053	0.788	-0.633	-1.137
15	0.853	-1.563	0.264	-1.952

Standard thresholds

P-value	Threshold
0.001	4.40261
0.0005	5.32546
0.0001	7.22146