| Motif | TPRX1.H13CORE.0.PSGIB.A |
| Gene (human) | TPRX1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | TPRX1.H13CORE.0.PSGIB.A |
| Gene (human) | TPRX1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 15 |
| Consensus | nbnTAATCCbhWhdn |
| GC content | 36.62% |
| Information content (bits; total / per base) | 12.773 / 0.852 |
| Data sources | ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM |
| Aligned words | 7580 |
| Previous names |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|
| Overall | 2 (4) | 0.93 | 0.943 | 0.876 | 0.903 | 0.769 | 0.779 | 92.748 | 104.886 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| overall, 4 experiments | median | 0.999 | 0.998 | 0.996 | 0.994 | 0.99 | 0.986 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | |
| Lysate, 1 experiments | median | 0.997 | 0.996 | 0.992 | 0.989 | 0.982 | 0.974 |
| best | 0.997 | 0.996 | 0.992 | 0.989 | 0.982 | 0.974 | |
| IVT, 1 experiments | median | 0.957 | 0.945 | 0.843 | 0.831 | 0.698 | 0.713 |
| best | 0.957 | 0.945 | 0.843 | 0.831 | 0.698 | 0.713 | |
| GFPIVT, 2 experiments | median | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 |
| best | 1.0 | 1.0 | 1.0 | 1.0 | 0.999 | 0.999 | |
| Genomic HT-SELEX benchmarking | Centrality | pseudo-auROC | auROC | auPR | |
|---|---|---|---|---|---|
| overall, 3 experiments | median | 561.495 | 0.939 | 0.958 | 0.942 |
| best | 761.027 | 0.97 | 0.984 | 0.962 | |
| Lysate, 1 experiments | median | 452.523 | 0.904 | 0.913 | 0.812 |
| best | 561.495 | 0.914 | 0.935 | 0.867 | |
| GFPIVT, 2 experiments | median | 639.481 | 0.946 | 0.972 | 0.947 |
| best | 761.027 | 0.97 | 0.984 | 0.962 | |
| SMiLE-Seq benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.874 | 0.837 | 0.746 | 0.728 | 0.625 | 0.64 |
| best | 0.907 | 0.871 | 0.782 | 0.762 | 0.649 | 0.663 | |
| PBM benchmarking | auROC, QNZS | auPR, QNZS | auROC, SD | auPR, SD | |
|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.945 | 0.213 | 0.95 | 0.216 |
| best | 0.969 | 0.219 | 0.965 | 0.263 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | Paired-related HD {3.1.3} (TFClass) |
| TF subfamily | TPRX {3.1.3.26} (TFClass) |
| TFClass ID | TFClass: 3.1.3.26.1 |
| HGNC | HGNC:32174 |
| MGI | |
| EntrezGene (human) | GeneID:284355 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | TPRX1_HUMAN |
| UniProt ID (mouse) | |
| UniProt AC (human) | Q8N7U7 (TFClass) |
| UniProt AC (mouse) | |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 0 mouse |
| HT-SELEX | 4 overall: 1 Lysate, 1 IVT, 2 GFPIVT |
| Genomic HT-SELEX | 3 overall: 1 Lysate, 0 IVT, 2 GFPIVT |
| SMiLE-Seq | 2 |
| PBM | 6 |
| PCM | TPRX1.H13CORE.0.PSGIB.A.pcm |
| PWM | TPRX1.H13CORE.0.PSGIB.A.pwm |
| PFM | TPRX1.H13CORE.0.PSGIB.A.pfm |
| Threshold to P-value map | TPRX1.H13CORE.0.PSGIB.A.thr |
| Motif in other formats | |
| JASPAR format | TPRX1.H13CORE.0.PSGIB.A_jaspar_format.txt |
| MEME format | TPRX1.H13CORE.0.PSGIB.A_meme_format.meme |
| Transfac format | TPRX1.H13CORE.0.PSGIB.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 1883.25 | 2168.25 | 1751.25 | 1777.25 |
| 02 | 1016.5 | 2078.5 | 3300.5 | 1184.5 |
| 03 | 2259.0 | 1710.0 | 1211.0 | 2400.0 |
| 04 | 49.0 | 11.0 | 5.0 | 7515.0 |
| 05 | 7449.0 | 3.0 | 82.0 | 46.0 |
| 06 | 7580.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 0.0 | 41.0 | 7539.0 |
| 08 | 0.0 | 7578.0 | 2.0 | 0.0 |
| 09 | 151.0 | 6232.0 | 546.0 | 651.0 |
| 10 | 505.0 | 1215.0 | 3803.0 | 2057.0 |
| 11 | 3022.0 | 1235.0 | 711.0 | 2612.0 |
| 12 | 1080.0 | 554.0 | 589.0 | 5357.0 |
| 13 | 2029.0 | 1116.0 | 860.0 | 3575.0 |
| 14 | 4186.0 | 865.0 | 976.0 | 1553.0 |
| 15 | 2035.25 | 1349.25 | 1644.25 | 2551.25 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.248 | 0.286 | 0.231 | 0.234 |
| 02 | 0.134 | 0.274 | 0.435 | 0.156 |
| 03 | 0.298 | 0.226 | 0.16 | 0.317 |
| 04 | 0.006 | 0.001 | 0.001 | 0.991 |
| 05 | 0.983 | 0.0 | 0.011 | 0.006 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.005 | 0.995 |
| 08 | 0.0 | 1.0 | 0.0 | 0.0 |
| 09 | 0.02 | 0.822 | 0.072 | 0.086 |
| 10 | 0.067 | 0.16 | 0.502 | 0.271 |
| 11 | 0.399 | 0.163 | 0.094 | 0.345 |
| 12 | 0.142 | 0.073 | 0.078 | 0.707 |
| 13 | 0.268 | 0.147 | 0.113 | 0.472 |
| 14 | 0.552 | 0.114 | 0.129 | 0.205 |
| 15 | 0.269 | 0.178 | 0.217 | 0.337 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.006 | 0.135 | -0.079 | -0.064 |
| 02 | -0.622 | 0.092 | 0.554 | -0.469 |
| 03 | 0.176 | -0.103 | -0.447 | 0.236 |
| 04 | -3.612 | -4.965 | -5.569 | 1.377 |
| 05 | 1.368 | -5.893 | -3.115 | -3.672 |
| 06 | 1.385 | -6.745 | -6.745 | -6.745 |
| 07 | -6.745 | -6.745 | -3.782 | 1.38 |
| 08 | -6.745 | 1.385 | -6.105 | -6.745 |
| 09 | -2.516 | 1.19 | -1.241 | -1.066 |
| 10 | -1.319 | -0.444 | 0.696 | 0.082 |
| 11 | 0.466 | -0.428 | -0.978 | 0.321 |
| 12 | -0.561 | -1.227 | -1.166 | 1.038 |
| 13 | 0.068 | -0.529 | -0.789 | 0.634 |
| 14 | 0.792 | -0.783 | -0.662 | -0.199 |
| 15 | 0.071 | -0.339 | -0.142 | 0.297 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.10006 |
| 0.0005 | 4.67276 |
| 0.0001 | 7.38031 |