| Motif | TPRX1.H13INVIVO.0.PSGIB.A |
| Gene (human) | TPRX1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | TPRX1.H13INVIVO.0.PSGIB.A |
| Gene (human) | TPRX1 (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 13 |
| Consensus | hWTAATCYYTTWW |
| GC content | 21.18% |
| Information content (bits; total / per base) | 14.371 / 1.105 |
| Data sources | ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM |
| Aligned words | 500 |
| Previous names |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|
| Overall | 2 (4) | 0.954 | 0.964 | 0.901 | 0.926 | 0.753 | 0.773 | 138.31 | 151.143 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| overall, 4 experiments | median | 0.986 | 0.977 | 0.974 | 0.961 | 0.955 | 0.937 |
| best | 0.997 | 0.995 | 0.99 | 0.986 | 0.981 | 0.973 | |
| Lysate, 1 experiments | median | 0.976 | 0.96 | 0.96 | 0.939 | 0.93 | 0.903 |
| best | 0.976 | 0.96 | 0.96 | 0.939 | 0.93 | 0.903 | |
| IVT, 1 experiments | median | 0.889 | 0.859 | 0.764 | 0.747 | 0.636 | 0.651 |
| best | 0.889 | 0.859 | 0.764 | 0.747 | 0.636 | 0.651 | |
| GFPIVT, 2 experiments | median | 0.996 | 0.994 | 0.99 | 0.984 | 0.98 | 0.972 |
| best | 0.997 | 0.995 | 0.99 | 0.986 | 0.981 | 0.973 | |
| Genomic HT-SELEX benchmarking | Centrality | pseudo-auROC | auROC | auPR | |
|---|---|---|---|---|---|
| overall, 3 experiments | median | 403.523 | 0.867 | 0.918 | 0.866 |
| best | 677.638 | 0.931 | 0.951 | 0.92 | |
| Lysate, 1 experiments | median | 199.959 | 0.737 | 0.682 | 0.494 |
| best | 280.31 | 0.754 | 0.732 | 0.569 | |
| GFPIVT, 2 experiments | median | 539.781 | 0.885 | 0.921 | 0.881 |
| best | 677.638 | 0.931 | 0.951 | 0.92 | |
| SMiLE-Seq benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 2 experiments | median | 0.813 | 0.763 | 0.699 | 0.675 | 0.603 | 0.608 |
| best | 0.834 | 0.781 | 0.724 | 0.694 | 0.616 | 0.62 | |
| PBM benchmarking | auROC, QNZS | auPR, QNZS | auROC, SD | auPR, SD | |
|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.865 | 0.098 | 0.896 | 0.146 |
| best | 0.898 | 0.117 | 0.934 | 0.164 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | Paired-related HD {3.1.3} (TFClass) |
| TF subfamily | TPRX {3.1.3.26} (TFClass) |
| TFClass ID | TFClass: 3.1.3.26.1 |
| HGNC | HGNC:32174 |
| MGI | |
| EntrezGene (human) | GeneID:284355 (SSTAR profile) |
| EntrezGene (mouse) | |
| UniProt ID (human) | TPRX1_HUMAN |
| UniProt ID (mouse) | |
| UniProt AC (human) | Q8N7U7 (TFClass) |
| UniProt AC (mouse) | |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 0 mouse |
| HT-SELEX | 4 overall: 1 Lysate, 1 IVT, 2 GFPIVT |
| Genomic HT-SELEX | 3 overall: 1 Lysate, 0 IVT, 2 GFPIVT |
| SMiLE-Seq | 2 |
| PBM | 6 |
| PCM | TPRX1.H13INVIVO.0.PSGIB.A.pcm |
| PWM | TPRX1.H13INVIVO.0.PSGIB.A.pwm |
| PFM | TPRX1.H13INVIVO.0.PSGIB.A.pfm |
| Threshold to P-value map | TPRX1.H13INVIVO.0.PSGIB.A.thr |
| Motif in other formats | |
| JASPAR format | TPRX1.H13INVIVO.0.PSGIB.A_jaspar_format.txt |
| MEME format | TPRX1.H13INVIVO.0.PSGIB.A_meme_format.meme |
| Transfac format | TPRX1.H13INVIVO.0.PSGIB.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 94.0 | 96.0 | 93.0 | 217.0 |
| 02 | 261.0 | 45.0 | 31.0 | 163.0 |
| 03 | 12.0 | 1.0 | 1.0 | 486.0 |
| 04 | 488.0 | 0.0 | 5.0 | 7.0 |
| 05 | 499.0 | 1.0 | 0.0 | 0.0 |
| 06 | 3.0 | 2.0 | 20.0 | 475.0 |
| 07 | 6.0 | 484.0 | 4.0 | 6.0 |
| 08 | 11.0 | 347.0 | 1.0 | 141.0 |
| 09 | 76.0 | 83.0 | 4.0 | 337.0 |
| 10 | 95.0 | 9.0 | 13.0 | 383.0 |
| 11 | 78.0 | 13.0 | 5.0 | 404.0 |
| 12 | 244.0 | 24.0 | 25.0 | 207.0 |
| 13 | 262.0 | 45.0 | 25.0 | 168.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.188 | 0.192 | 0.186 | 0.434 |
| 02 | 0.522 | 0.09 | 0.062 | 0.326 |
| 03 | 0.024 | 0.002 | 0.002 | 0.972 |
| 04 | 0.976 | 0.0 | 0.01 | 0.014 |
| 05 | 0.998 | 0.002 | 0.0 | 0.0 |
| 06 | 0.006 | 0.004 | 0.04 | 0.95 |
| 07 | 0.012 | 0.968 | 0.008 | 0.012 |
| 08 | 0.022 | 0.694 | 0.002 | 0.282 |
| 09 | 0.152 | 0.166 | 0.008 | 0.674 |
| 10 | 0.19 | 0.018 | 0.026 | 0.766 |
| 11 | 0.156 | 0.026 | 0.01 | 0.808 |
| 12 | 0.488 | 0.048 | 0.05 | 0.414 |
| 13 | 0.524 | 0.09 | 0.05 | 0.336 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.281 | -0.26 | -0.291 | 0.546 |
| 02 | 0.73 | -1.0 | -1.358 | 0.263 |
| 03 | -2.234 | -3.903 | -3.903 | 1.349 |
| 04 | 1.353 | -4.4 | -2.961 | -2.694 |
| 05 | 1.375 | -3.903 | -4.4 | -4.4 |
| 06 | -3.325 | -3.573 | -1.77 | 1.326 |
| 07 | -2.819 | 1.345 | -3.126 | -2.819 |
| 08 | -2.311 | 1.013 | -3.903 | 0.119 |
| 09 | -0.49 | -0.403 | -3.126 | 0.984 |
| 10 | -0.271 | -2.484 | -2.163 | 1.111 |
| 11 | -0.464 | -2.163 | -2.961 | 1.165 |
| 12 | 0.663 | -1.6 | -1.561 | 0.5 |
| 13 | 0.734 | -1.0 | -1.561 | 0.293 |
| P-value | Threshold |
|---|---|
| 0.001 | 3.15241 |
| 0.0005 | 4.33556 |
| 0.0001 | 6.784165 |