ZBED5.H13CORE.0.PSGIB.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBED5.H13CORE.0.PSGIB.A
Gene (human)	ZBED5 (GeneCards)
Gene synonyms (human)	Buster1
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	10
Consensus	nhGGhACMhn
GC content	64.21%
Information content (bits; total / per base)	9.423 / 0.942
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM
Aligned words	649
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	3 (3)	0.87	0.87	0.773	0.789	0.67	0.682	116.824	154.18

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 5 experiments	median	0.999	0.999	0.888	0.899	0.717	0.75
overall, 5 experiments	best	1.0	1.0	1.0	0.999	0.998	0.998
Lysate, 2 experiments	median	0.865	0.879	0.752	0.768	0.651	0.669
Lysate, 2 experiments	best	0.999	0.999	0.888	0.899	0.717	0.75
IVT, 1 experiments	median	1.0	1.0	1.0	0.999	0.992	0.992
IVT, 1 experiments	best	1.0	1.0	1.0	0.999	0.992	0.992
GFPIVT, 2 experiments	median	0.833	0.842	0.793	0.798	0.773	0.778
GFPIVT, 2 experiments	best	1.0	1.0	1.0	0.999	0.998	0.998

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 2 experiments	median	91.463	0.809	0.837	0.704
overall, 2 experiments	best	404.921	0.907	0.939	0.832
Lysate, 1 experiments	median	74.102	0.727	0.753	0.675
Lysate, 1 experiments	best	108.824	0.741	0.787	0.71
GFPIVT, 1 experiments	median	197.824	0.883	0.938	0.83
GFPIVT, 1 experiments	best	404.921	0.907	0.939	0.832

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.591	0.573	0.554	0.544	0.533	0.529
Overall, 2 experiments	best	0.611	0.601	0.563	0.558	0.538	0.537

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 3 experiments	median	0.889	0.47	0.911	0.501
Overall, 3 experiments	best	0.889	0.47	0.938	0.533

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	BED zinc finger {2.3.5} (TFClass)
TF subfamily	{2.3.5.0} (TFClass)
TFClass ID	TFClass: 2.3.5.0.5
HGNC	HGNC:30803
MGI
EntrezGene (human)	GeneID:58486 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZBED5_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q49AG3 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	no

ChIP-Seq	3 human, 0 mouse
HT-SELEX	5 overall: 2 Lysate, 1 IVT, 2 GFPIVT
Genomic HT-SELEX	2 overall: 1 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	2
PBM	3

PCM	ZBED5.H13CORE.0.PSGIB.A.pcm
PWM	ZBED5.H13CORE.0.PSGIB.A.pwm
PFM	ZBED5.H13CORE.0.PSGIB.A.pfm
Threshold to P-value map	ZBED5.H13CORE.0.PSGIB.A.thr
Motif in other formats
JASPAR format	ZBED5.H13CORE.0.PSGIB.A_jaspar_format.txt
MEME format	ZBED5.H13CORE.0.PSGIB.A_meme_format.meme
Transfac format	ZBED5.H13CORE.0.PSGIB.A_transfac_format.txt
Homer format	ZBED5.H13CORE.0.PSGIB.A_homer_format_0.001.txt ZBED5.H13CORE.0.PSGIB.A_homer_format_0.0005.txt ZBED5.H13CORE.0.PSGIB.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	202.0	140.0	198.0	109.0
02	94.0	370.0	81.0	104.0
03	0.0	0.0	649.0	0.0
04	3.0	2.0	630.0	14.0
05	256.0	169.0	13.0	211.0
06	643.0	1.0	3.0	2.0
07	2.0	634.0	9.0	4.0
08	99.0	483.0	16.0	51.0
09	78.0	357.0	76.0	138.0
10	120.0	215.0	121.0	193.0

PFM

	A	C	G	T
01	0.311	0.216	0.305	0.168
02	0.145	0.57	0.125	0.16
03	0.0	0.0	1.0	0.0
04	0.005	0.003	0.971	0.022
05	0.394	0.26	0.02	0.325
06	0.991	0.002	0.005	0.003
07	0.003	0.977	0.014	0.006
08	0.153	0.744	0.025	0.079
09	0.12	0.55	0.117	0.213
10	0.185	0.331	0.186	0.297

PWM

	A	C	G	T
01	0.217	-0.146	0.197	-0.393
02	-0.539	0.819	-0.685	-0.439
03	-4.617	-4.617	1.379	-4.617
04	-3.569	-3.813	1.349	-2.351
05	0.452	0.04	-2.417	0.26
06	1.37	-4.136	-3.569	-3.813
07	-3.813	1.356	-2.736	-3.373
08	-0.488	1.084	-2.23	-1.136
09	-0.722	0.783	-0.747	-0.16
10	-0.298	0.279	-0.29	0.172

Standard thresholds

P-value	Threshold
0.001	5.21693
0.0005	6.03039
0.0001	7.3926