ZBED5.H13INVIVO.0.PSGIB.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBED5.H13INVIVO.0.PSGIB.A
Gene (human)	ZBED5 (GeneCards)
Gene synonyms (human)	Buster1
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	12
Consensus	bSvbGGMACCCY
GC content	72.09%
Information content (bits; total / per base)	13.023 / 1.085
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq + PBM
Aligned words	1000
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	3 (3)	0.864	0.865	0.768	0.78	0.705	0.711	127.745	176.824

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 5 experiments	median	0.997	0.996	0.897	0.904	0.715	0.752
overall, 5 experiments	best	1.0	1.0	0.999	0.998	0.997	0.995
Lysate, 2 experiments	median	0.869	0.88	0.75	0.769	0.636	0.665
Lysate, 2 experiments	best	0.997	0.996	0.897	0.904	0.715	0.752
IVT, 1 experiments	median	1.0	1.0	0.999	0.998	0.991	0.989
IVT, 1 experiments	best	1.0	1.0	0.999	0.998	0.991	0.989
GFPIVT, 2 experiments	median	0.839	0.843	0.793	0.798	0.774	0.777
GFPIVT, 2 experiments	best	1.0	1.0	0.999	0.998	0.997	0.995

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 2 experiments	median	104.09	0.826	0.857	0.763
overall, 2 experiments	best	453.155	0.935	0.959	0.871
Lysate, 1 experiments	median	81.0	0.741	0.793	0.762
Lysate, 1 experiments	best	127.18	0.755	0.822	0.763
GFPIVT, 1 experiments	median	232.569	0.918	0.943	0.849
GFPIVT, 1 experiments	best	453.155	0.935	0.959	0.871

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.594	0.572	0.553	0.544	0.53	0.528
Overall, 2 experiments	best	0.617	0.6	0.572	0.561	0.538	0.538

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 4 experiments	median	0.88	0.329	0.897	0.294
Overall, 4 experiments	best	0.881	0.34	0.902	0.318

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	BED zinc finger {2.3.5} (TFClass)
TF subfamily	{2.3.5.0} (TFClass)
TFClass ID	TFClass: 2.3.5.0.5
HGNC	HGNC:30803
MGI
EntrezGene (human)	GeneID:58486 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZBED5_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q49AG3 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	no

ChIP-Seq	3 human, 0 mouse
HT-SELEX	5 overall: 2 Lysate, 1 IVT, 2 GFPIVT
Genomic HT-SELEX	2 overall: 1 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	2
PBM	4

PCM	ZBED5.H13INVIVO.0.PSGIB.A.pcm
PWM	ZBED5.H13INVIVO.0.PSGIB.A.pwm
PFM	ZBED5.H13INVIVO.0.PSGIB.A.pfm
Threshold to P-value map	ZBED5.H13INVIVO.0.PSGIB.A.thr
Motif in other formats
JASPAR format	ZBED5.H13INVIVO.0.PSGIB.A_jaspar_format.txt
MEME format	ZBED5.H13INVIVO.0.PSGIB.A_meme_format.meme
Transfac format	ZBED5.H13INVIVO.0.PSGIB.A_transfac_format.txt
Homer format	ZBED5.H13INVIVO.0.PSGIB.A_homer_format_0.001.txt ZBED5.H13INVIVO.0.PSGIB.A_homer_format_0.0005.txt ZBED5.H13INVIVO.0.PSGIB.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	117.0	529.0	182.0	172.0
02	95.0	604.0	172.0	129.0
03	334.0	266.0	335.0	65.0
04	142.0	469.0	184.0	205.0
05	2.0	0.0	993.0	5.0
06	2.0	8.0	915.0	75.0
07	457.0	450.0	36.0	57.0
08	999.0	0.0	0.0	1.0
09	0.0	998.0	0.0	2.0
10	41.0	959.0	0.0	0.0
11	2.0	974.0	4.0	20.0
12	138.0	540.0	33.0	289.0

PFM

	A	C	G	T
01	0.117	0.529	0.182	0.172
02	0.095	0.604	0.172	0.129
03	0.334	0.266	0.335	0.065
04	0.142	0.469	0.184	0.205
05	0.002	0.0	0.993	0.005
06	0.002	0.008	0.915	0.075
07	0.457	0.45	0.036	0.057
08	0.999	0.0	0.0	0.001
09	0.0	0.998	0.0	0.002
10	0.041	0.959	0.0	0.0
11	0.002	0.974	0.004	0.02
12	0.138	0.54	0.033	0.289

PWM

	A	C	G	T
01	-0.752	0.746	-0.315	-0.371
02	-0.956	0.878	-0.371	-0.655
03	0.288	0.062	0.291	-1.328
04	-0.56	0.626	-0.304	-0.197
05	-4.213	-4.982	1.374	-3.622
06	-4.213	-3.253	1.292	-1.188
07	0.6	0.585	-1.898	-1.455
08	1.38	-4.982	-4.982	-4.525
09	-4.982	1.379	-4.982	-4.213
10	-1.774	1.339	-4.982	-4.982
11	-4.213	1.355	-3.783	-2.45
12	-0.589	0.766	-1.981	0.144

Standard thresholds

P-value	Threshold
0.001	3.30717
0.0005	4.54758
0.0001	7.25389