ZBT7A.H13RSNP.0.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZBT7A.H13RSNP.0.P.B
Gene (human)	ZBTB7A (GeneCards)
Gene synonyms (human)	FBI1, LRF, ZBTB7, ZNF857A
Gene (mouse)	Zbtb7a
Gene synonyms (mouse)	Lrf, Zbtb7
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	8
Consensus	dRGGGKCK
GC content	74.18%
Information content (bits; total / per base)	9.991 / 1.249
Data sources	ChIP-Seq
Aligned words	1003
Previous names	ZBT7A.H12RSNP.0.P.B

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	9 (61)	0.77	0.816	0.565	0.628	0.589	0.668	1.182	1.397	106.745	185.523

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.822	0.746	0.816	0.741	0.772	0.709
Overall, 2 experiments	best	0.884	0.822	0.843	0.785	0.788	0.737
Methyl HT-SELEX, 1 experiments	median	0.884	0.822	0.843	0.785	0.788	0.737
Methyl HT-SELEX, 1 experiments	best	0.884	0.822	0.843	0.785	0.788	0.737
Non-Methyl HT-SELEX, 1 experiments	median	0.759	0.671	0.79	0.696	0.756	0.681
Non-Methyl HT-SELEX, 1 experiments	best	0.759	0.671	0.79	0.696	0.756	0.681

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	10.263	2.089	0.159	0.122

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZBTB7 {2.3.3.8} (TFClass)
TFClass ID	TFClass: 2.3.3.8.1
HGNC	HGNC:18078
MGI	MGI:1335091
EntrezGene (human)	GeneID:51341 (SSTAR profile)
EntrezGene (mouse)	GeneID:16969 (SSTAR profile)
UniProt ID (human)	ZBT7A_HUMAN
UniProt ID (mouse)	ZBT7A_MOUSE
UniProt AC (human)	O95365 (TFClass)
UniProt AC (mouse)	O88939 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	9 human, 0 mouse
HT-SELEX	1
Methyl-HT-SELEX	1
Genomic HT-SELEX	0 overall: 0 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZBT7A.H13RSNP.0.P.B.pcm
PWM	ZBT7A.H13RSNP.0.P.B.pwm
PFM	ZBT7A.H13RSNP.0.P.B.pfm
Threshold to P-value map	ZBT7A.H13RSNP.0.P.B.thr
Motif in other formats
JASPAR format	ZBT7A.H13RSNP.0.P.B_jaspar_format.txt
MEME format	ZBT7A.H13RSNP.0.P.B_meme_format.meme
Transfac format	ZBT7A.H13RSNP.0.P.B_transfac_format.txt
Homer format	ZBT7A.H13RSNP.0.P.B_homer_format_0.001.txt ZBT7A.H13RSNP.0.P.B_homer_format_0.0005.txt ZBT7A.H13RSNP.0.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	258.0	128.0	465.0	152.0
02	362.0	2.0	634.0	5.0
03	3.0	1.0	949.0	50.0
04	5.0	0.0	997.0	1.0
05	5.0	0.0	995.0	3.0
06	6.0	0.0	415.0	582.0
07	4.0	984.0	3.0	12.0
08	41.0	172.0	207.0	583.0

PFM

	A	C	G	T
01	0.257	0.128	0.464	0.152
02	0.361	0.002	0.632	0.005
03	0.003	0.001	0.946	0.05
04	0.005	0.0	0.994	0.001
05	0.005	0.0	0.992	0.003
06	0.006	0.0	0.414	0.58
07	0.004	0.981	0.003	0.012
08	0.041	0.171	0.206	0.581

PWM

	A	C	G	T
01	0.028	-0.666	0.614	-0.496
02	0.365	-4.216	0.923	-3.625
03	-3.978	-4.528	1.326	-1.585
04	-3.625	-4.985	1.375	-4.528
05	-3.625	-4.985	1.373	-3.978
06	-3.487	-4.985	0.501	0.838
07	-3.786	1.362	-3.978	-2.912
08	-1.776	-0.374	-0.19	0.84

Standard thresholds

P-value	Threshold
0.001	4.59485
0.0005	6.24232
0.0001	7.591625