ZFAT.H13INVITRO.0.PSGI.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZFAT.H13INVITRO.0.PSGI.A
Gene (human)	ZFAT (GeneCards)
Gene synonyms (human)	KIAA1485, ZFAT1, ZNF406
Gene (mouse)	Zfat
Gene synonyms (mouse)	Gm922, Zfat1, Zfp406, Znf406
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	16
Consensus	hvGCAGATTCGYCAhd
GC content	51.46%
Information content (bits; total / per base)	22.494 / 1.406
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX + SMiLe-Seq
Aligned words	9892
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (4)	0.85	0.861	0.764	0.783	0.776	0.788	41.842	61.161

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
GFPIVT, 1 experiments	median	1.0	1.0	0.999	0.999	0.887	0.904
GFPIVT, 1 experiments	best	1.0	1.0	0.999	0.999	0.887	0.904

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
GFPIVT, 1 experiments	median	128.718	0.759	0.812	0.787
GFPIVT, 1 experiments	best	160.268	0.787	0.837	0.816

SMiLE-Seq benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 1 experiments	median	0.995	0.993	0.948	0.944	0.763	0.793
Overall, 1 experiments	best	0.995	0.993	0.948	0.944	0.763	0.793

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	HINFP-like {2.3.4.21} (TFClass)
TFClass ID	TFClass: 2.3.4.21.2
HGNC	HGNC:19899
MGI	MGI:2681865
EntrezGene (human)	GeneID:57623 (SSTAR profile)
EntrezGene (mouse)	GeneID:380993 (SSTAR profile)
UniProt ID (human)	ZFAT_HUMAN
UniProt ID (mouse)	ZFAT_MOUSE
UniProt AC (human)	Q9P243 (TFClass)
UniProt AC (mouse)	Q7TS63 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	1 overall: 0 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	1
PBM	0

PCM	ZFAT.H13INVITRO.0.PSGI.A.pcm
PWM	ZFAT.H13INVITRO.0.PSGI.A.pwm
PFM	ZFAT.H13INVITRO.0.PSGI.A.pfm
Threshold to P-value map	ZFAT.H13INVITRO.0.PSGI.A.thr
Motif in other formats
JASPAR format	ZFAT.H13INVITRO.0.PSGI.A_jaspar_format.txt
MEME format	ZFAT.H13INVITRO.0.PSGI.A_meme_format.meme
Transfac format	ZFAT.H13INVITRO.0.PSGI.A_transfac_format.txt
Homer format	ZFAT.H13INVITRO.0.PSGI.A_homer_format_0.001.txt ZFAT.H13INVITRO.0.PSGI.A_homer_format_0.0005.txt ZFAT.H13INVITRO.0.PSGI.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1245.75	5622.75	650.75	2372.75
02	3001.75	4243.75	1986.75	659.75
03	166.0	48.0	9659.0	19.0
04	5.0	9749.0	3.0	135.0
05	9765.0	39.0	1.0	87.0
06	0.0	90.0	9801.0	1.0
07	9814.0	0.0	0.0	78.0
08	1.0	0.0	0.0	9891.0
09	1.0	0.0	0.0	9891.0
10	1.0	9890.0	0.0	1.0
11	3.0	2.0	9887.0	0.0
12	1475.0	2994.0	61.0	5362.0
13	131.0	9296.0	150.0	315.0
14	9531.0	37.0	218.0	106.0
15	3540.0	4122.0	560.0	1670.0
16	5015.5	734.5	1606.5	2535.5

PFM

	A	C	G	T
01	0.126	0.568	0.066	0.24
02	0.303	0.429	0.201	0.067
03	0.017	0.005	0.976	0.002
04	0.001	0.986	0.0	0.014
05	0.987	0.004	0.0	0.009
06	0.0	0.009	0.991	0.0
07	0.992	0.0	0.0	0.008
08	0.0	0.0	0.0	1.0
09	0.0	0.0	0.0	1.0
10	0.0	1.0	0.0	0.0
11	0.0	0.0	0.999	0.0
12	0.149	0.303	0.006	0.542
13	0.013	0.94	0.015	0.032
14	0.964	0.004	0.022	0.011
15	0.358	0.417	0.057	0.169
16	0.507	0.074	0.162	0.256

PWM

	A	C	G	T
01	-0.685	0.821	-1.332	-0.041
02	0.194	0.54	-0.219	-1.319
03	-2.688	-3.896	1.362	-4.755
04	-5.826	1.371	-6.146	-2.892
05	1.373	-4.093	-6.62	-3.322
06	-6.981	-3.289	1.376	-6.62
07	1.378	-6.981	-6.981	-3.428
08	-6.62	-6.981	-6.981	1.385
09	-6.62	-6.981	-6.981	1.385
10	-6.62	1.385	-6.981	-6.62
11	-6.146	-6.356	1.385	-6.981
12	-0.516	0.191	-3.666	0.773
13	-2.922	1.323	-2.788	-2.054
14	1.348	-4.143	-2.419	-3.129
15	0.358	0.511	-1.482	-0.392
16	0.707	-1.212	-0.431	0.025

Standard thresholds

P-value	Threshold
0.001	-6.66929
0.0005	-4.48579
0.0001	0.18376