ZGLP1.H13INVITRO.0.SGB.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZGLP1.H13INVITRO.0.SGB.A
Gene (human)	ZGLP1 (GeneCards)
Gene synonyms (human)	GLP1
Gene (mouse)	Zglp1
Gene synonyms (mouse)	Glp1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	14
Consensus	dhvRTGATCGhKbd
GC content	46.91%
Information content (bits; total / per base)	13.199 / 0.943
Data sources	HT-SELEX + Genomic HT-SELEX + PBM
Aligned words	7086
Previous names

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 3 experiments	median	0.945	0.918	0.876	0.847	0.736	0.737
overall, 3 experiments	best	0.979	0.969	0.932	0.915	0.783	0.791
Lysate, 2 experiments	median	0.957	0.942	0.873	0.858	0.733	0.742
Lysate, 2 experiments	best	0.979	0.969	0.932	0.915	0.783	0.791
IVT, 1 experiments	median	0.945	0.918	0.876	0.847	0.736	0.737
IVT, 1 experiments	best	0.945	0.918	0.876	0.847	0.736	0.737

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
Lysate, 2 experiments	median	126.165	0.351	0.813	0.664
Lysate, 2 experiments	best	163.921	0.408	0.844	0.713

PBM benchmarking		auROC, QNZS	auPR, QNZS	auROC, SD	auPR, SD
Overall, 8 experiments	median	0.944	0.057	0.939	0.194
Overall, 8 experiments	best	0.955	0.188	0.958	0.299

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	Other C4 zinc finger-type factors {2.2} (TFClass)
TF family	C4-GATA-related {2.2.1} (TFClass)
TF subfamily	GATA single {2.2.1.2} (TFClass)
TFClass ID	TFClass: 2.2.1.2.8
HGNC	HGNC:37245
MGI	MGI:3696042
EntrezGene (human)	GeneID:100125288 (SSTAR profile)
EntrezGene (mouse)	GeneID:100009600 (SSTAR profile)
UniProt ID (human)	ZGLP1_HUMAN
UniProt ID (mouse)	ZGLP1_MOUSE
UniProt AC (human)	P0C6A0 (TFClass)
UniProt AC (mouse)	Q1WG82 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3 overall: 2 Lysate, 1 IVT, 0 GFPIVT
Genomic HT-SELEX	2 overall: 2 Lysate, 0 IVT, 0 GFPIVT
SMiLE-Seq	0
PBM	8

PCM	ZGLP1.H13INVITRO.0.SGB.A.pcm
PWM	ZGLP1.H13INVITRO.0.SGB.A.pwm
PFM	ZGLP1.H13INVITRO.0.SGB.A.pfm
Threshold to P-value map	ZGLP1.H13INVITRO.0.SGB.A.thr
Motif in other formats
JASPAR format	ZGLP1.H13INVITRO.0.SGB.A_jaspar_format.txt
MEME format	ZGLP1.H13INVITRO.0.SGB.A_meme_format.meme
Transfac format	ZGLP1.H13INVITRO.0.SGB.A_transfac_format.txt
Homer format	ZGLP1.H13INVITRO.0.SGB.A_homer_format_0.001.txt ZGLP1.H13INVITRO.0.SGB.A_homer_format_0.0005.txt ZGLP1.H13INVITRO.0.SGB.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2845.5	1156.5	1733.5	1350.5
02	905.5	2377.5	640.5	3162.5
03	962.0	1623.0	3856.0	645.0
04	5030.0	310.0	1266.0	480.0
05	6.0	1467.0	6.0	5607.0
06	0.0	19.0	7067.0	0.0
07	7086.0	0.0	0.0	0.0
08	0.0	0.0	0.0	7086.0
09	0.0	7085.0	0.0	1.0
10	1585.0	5.0	5480.0	16.0
11	3883.0	991.0	908.0	1304.0
12	765.0	440.0	1064.0	4817.0
13	770.75	3610.75	1642.75	1061.75
14	2067.25	723.25	3066.25	1229.25

PFM

	A	C	G	T
01	0.402	0.163	0.245	0.191
02	0.128	0.336	0.09	0.446
03	0.136	0.229	0.544	0.091
04	0.71	0.044	0.179	0.068
05	0.001	0.207	0.001	0.791
06	0.0	0.003	0.997	0.0
07	1.0	0.0	0.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	1.0	0.0	0.0
10	0.224	0.001	0.773	0.002
11	0.548	0.14	0.128	0.184
12	0.108	0.062	0.15	0.68
13	0.109	0.51	0.232	0.15
14	0.292	0.102	0.433	0.173

PWM

	A	C	G	T
01	0.473	-0.426	-0.022	-0.271
02	-0.67	0.294	-1.015	0.579
03	-0.61	-0.087	0.777	-1.008
04	1.043	-1.737	-0.335	-1.302
05	-5.375	-0.188	-5.375	1.151
06	-6.685	-4.426	1.383	-6.685
07	1.385	-6.685	-6.685	-6.685
08	-6.685	-6.685	-6.685	1.385
09	-6.685	1.385	-6.685	-6.313
10	-0.111	-5.504	1.128	-4.579
11	0.784	-0.58	-0.667	-0.306
12	-0.838	-1.389	-0.509	1.0
13	-0.831	0.711	-0.075	-0.511
14	0.154	-0.894	0.548	-0.365

Standard thresholds

P-value	Threshold
0.001	2.39421
0.0005	4.45611
0.0001	7.33261