ZKSCAN4.H13CORE.0.SG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZKSCAN4.H13CORE.0.SG.A
Gene (human)	ZKSCAN4 (GeneCards)
Gene synonyms (human)	ZNF307, ZNF427
Gene (mouse)
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	18
Consensus	nbhYvAGTATATCCChhh
GC content	43.37%
Information content (bits; total / per base)	18.393 / 1.022
Data sources	HT-SELEX + Genomic HT-SELEX
Aligned words	9515
Previous names

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 3 experiments	median	1.0	1.0	1.0	1.0	0.897	0.917
overall, 3 experiments	best	1.0	1.0	1.0	1.0	1.0	1.0
IVT, 1 experiments	median	1.0	1.0	0.927	0.933	0.722	0.767
IVT, 1 experiments	best	1.0	1.0	0.927	0.933	0.722	0.767
GFPIVT, 2 experiments	median	1.0	1.0	1.0	1.0	0.949	0.959
GFPIVT, 2 experiments	best	1.0	1.0	1.0	1.0	1.0	1.0

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 3 experiments	median	186.886	0.855	0.87	0.884
overall, 3 experiments	best	636.523	0.93	0.953	0.941
Lysate, 1 experiments	median	83.921	0.53	0.563	0.611
Lysate, 1 experiments	best	136.155	0.561	0.582	0.626
GFPIVT, 2 experiments	median	389.422	0.905	0.916	0.925
GFPIVT, 2 experiments	best	636.523	0.93	0.953	0.941

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	More than 3 adjacent zinc fingers {2.3.3} (TFClass)
TF subfamily	ZKSCAN3-like {2.3.3.26} (TFClass)
TFClass ID	TFClass: 2.3.3.26.2
HGNC	HGNC:13854
MGI
EntrezGene (human)	GeneID:387032 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	ZKSC4_HUMAN
UniProt ID (mouse)
UniProt AC (human)	Q969J2 (TFClass)
UniProt AC (mouse)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 0 mouse
HT-SELEX	3 overall: 0 Lysate, 1 IVT, 2 GFPIVT
Genomic HT-SELEX	3 overall: 1 Lysate, 0 IVT, 2 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZKSCAN4.H13CORE.0.SG.A.pcm
PWM	ZKSCAN4.H13CORE.0.SG.A.pwm
PFM	ZKSCAN4.H13CORE.0.SG.A.pfm
Threshold to P-value map	ZKSCAN4.H13CORE.0.SG.A.thr
Motif in other formats
JASPAR format	ZKSCAN4.H13CORE.0.SG.A_jaspar_format.txt
MEME format	ZKSCAN4.H13CORE.0.SG.A_meme_format.meme
Transfac format	ZKSCAN4.H13CORE.0.SG.A_transfac_format.txt
Homer format	ZKSCAN4.H13CORE.0.SG.A_homer_format_0.001.txt ZKSCAN4.H13CORE.0.SG.A_homer_format_0.0005.txt ZKSCAN4.H13CORE.0.SG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2632.25	1939.25	2512.25	2431.25
02	839.75	3041.75	2414.75	3218.75
03	4013.0	3445.0	711.0	1346.0
04	319.0	4960.0	215.0	4021.0
05	4373.0	1131.0	3613.0	398.0
06	9016.0	63.0	384.0	52.0
07	242.0	9.0	9246.0	18.0
08	6.0	30.0	52.0	9427.0
09	6655.0	2796.0	20.0	44.0
10	4.0	32.0	3.0	9476.0
11	9418.0	37.0	32.0	28.0
12	103.0	470.0	648.0	8294.0
13	407.0	9019.0	38.0	51.0
14	17.0	8798.0	18.0	682.0
15	155.0	8772.0	61.0	527.0
16	5317.0	1518.0	924.0	1756.0
17	2406.25	3018.25	911.25	3179.25
18	2342.25	2167.25	1225.25	3780.25

PFM

	A	C	G	T
01	0.277	0.204	0.264	0.256
02	0.088	0.32	0.254	0.338
03	0.422	0.362	0.075	0.141
04	0.034	0.521	0.023	0.423
05	0.46	0.119	0.38	0.042
06	0.948	0.007	0.04	0.005
07	0.025	0.001	0.972	0.002
08	0.001	0.003	0.005	0.991
09	0.699	0.294	0.002	0.005
10	0.0	0.003	0.0	0.996
11	0.99	0.004	0.003	0.003
12	0.011	0.049	0.068	0.872
13	0.043	0.948	0.004	0.005
14	0.002	0.925	0.002	0.072
15	0.016	0.922	0.006	0.055
16	0.559	0.16	0.097	0.185
17	0.253	0.317	0.096	0.334
18	0.246	0.228	0.129	0.397

PWM

	A	C	G	T
01	0.101	-0.204	0.055	0.022
02	-1.039	0.246	0.015	0.302
03	0.523	0.37	-1.205	-0.569
04	-2.003	0.734	-2.394	0.525
05	0.608	-0.742	0.418	-1.783
06	1.332	-3.596	-1.819	-3.781
07	-2.277	-5.351	1.357	-4.765
08	-5.66	-4.301	-3.781	1.376
09	1.028	0.161	-4.671	-3.94
10	-5.936	-4.24	-6.109	1.381
11	1.375	-4.104	-4.24	-4.364
12	-3.119	-1.618	-1.298	1.248
13	-1.761	1.332	-4.079	-3.8
14	-4.816	1.307	-4.765	-1.247
15	-2.717	1.304	-3.628	-1.504
16	0.804	-0.449	-0.944	-0.303
17	0.011	0.238	-0.958	0.29
18	-0.015	-0.093	-0.663	0.463

Standard thresholds

P-value	Threshold
0.001	-0.05809
0.0005	1.51341
0.0001	4.80316