ZNF518B.H13INVIVO.0.PSG.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	ZNF518B.H13INVIVO.0.PSG.A
Gene (human)	ZNF518B (GeneCards)
Gene synonyms (human)	KIAA1729
Gene (mouse)	Znf518b
Gene synonyms (mouse)	Kiaa1729, Zfp518b
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	dGTAGAdbTCTAC
GC content	39.69%
Information content (bits; total / per base)	17.431 / 1.341
Data sources	ChIP-Seq + HT-SELEX + Genomic HT-SELEX
Aligned words	8963
Previous names

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	Centrality, median	Centrality, best
Overall	2 (2)	0.95	0.954	0.923	0.932	0.821	0.842	193.564	212.056

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
overall, 3 experiments	median	1.0	0.999	0.999	0.999	0.993	0.992
overall, 3 experiments	best	1.0	1.0	1.0	0.999	0.994	0.993
Lysate, 2 experiments	median	1.0	1.0	0.958	0.962	0.848	0.874
Lysate, 2 experiments	best	1.0	1.0	1.0	0.999	0.994	0.993
GFPIVT, 1 experiments	median	1.0	0.999	0.999	0.999	0.993	0.992
GFPIVT, 1 experiments	best	1.0	0.999	0.999	0.999	0.993	0.992

Genomic HT-SELEX benchmarking		Centrality	pseudo-auROC	auROC	auPR
overall, 3 experiments	median	836.638	0.863	0.952	0.953
overall, 3 experiments	best	1006.62	0.989	0.994	0.991
Lysate, 2 experiments	median	777.096	0.827	0.935	0.94
Lysate, 2 experiments	best	970.174	0.951	0.993	0.991
GFPIVT, 1 experiments	median	972.397	0.984	0.993	0.989
GFPIVT, 1 experiments	best	1006.62	0.989	0.994	0.991

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Multiple dispersed zinc fingers {2.3.4} (TFClass)
TF subfamily	ZNF518 {2.3.4.18} (TFClass)
TFClass ID	TFClass: 2.3.4.18.2
HGNC	HGNC:29365
MGI	MGI:2140750
EntrezGene (human)	GeneID:85460 (SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)	Z518B_HUMAN
UniProt ID (mouse)	Z518B_MOUSE
UniProt AC (human)	Q9C0D4 (TFClass)
UniProt AC (mouse)	B2RRE4 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	3 overall: 2 Lysate, 0 IVT, 1 GFPIVT
Genomic HT-SELEX	3 overall: 2 Lysate, 0 IVT, 1 GFPIVT
SMiLE-Seq	0
PBM	0

PCM	ZNF518B.H13INVIVO.0.PSG.A.pcm
PWM	ZNF518B.H13INVIVO.0.PSG.A.pwm
PFM	ZNF518B.H13INVIVO.0.PSG.A.pfm
Threshold to P-value map	ZNF518B.H13INVIVO.0.PSG.A.thr
Motif in other formats
JASPAR format	ZNF518B.H13INVIVO.0.PSG.A_jaspar_format.txt
MEME format	ZNF518B.H13INVIVO.0.PSG.A_meme_format.meme
Transfac format	ZNF518B.H13INVIVO.0.PSG.A_transfac_format.txt
Homer format	ZNF518B.H13INVIVO.0.PSG.A_homer_format_0.001.txt ZNF518B.H13INVIVO.0.PSG.A_homer_format_0.0005.txt ZNF518B.H13INVIVO.0.PSG.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1757.0	770.0	1824.0	4612.0
02	115.0	0.0	8846.0	2.0
03	1.0	0.0	0.0	8962.0
04	8951.0	0.0	12.0	0.0
05	0.0	0.0	8963.0	0.0
06	6676.0	2.0	1940.0	345.0
07	2104.0	598.0	2617.0	3644.0
08	1207.0	1299.0	2199.0	4258.0
09	308.0	1372.0	42.0	7241.0
10	1.0	8959.0	3.0	0.0
11	7.0	214.0	111.0	8631.0
12	8898.0	35.0	11.0	19.0
13	62.0	6398.0	28.0	2475.0

PFM

	A	C	G	T
01	0.196	0.086	0.204	0.515
02	0.013	0.0	0.987	0.0
03	0.0	0.0	0.0	1.0
04	0.999	0.0	0.001	0.0
05	0.0	0.0	1.0	0.0
06	0.745	0.0	0.216	0.038
07	0.235	0.067	0.292	0.407
08	0.135	0.145	0.245	0.475
09	0.034	0.153	0.005	0.808
10	0.0	1.0	0.0	0.0
11	0.001	0.024	0.012	0.963
12	0.993	0.004	0.001	0.002
13	0.007	0.714	0.003	0.276

PWM

	A	C	G	T
01	-0.243	-1.066	-0.206	0.721
02	-2.951	-6.894	1.372	-6.263
03	-6.529	-6.894	-6.894	1.385
04	1.384	-6.894	-5.057	-6.894
05	-6.894	-6.894	1.386	-6.894
06	1.091	-6.263	-0.144	-1.865
07	-0.063	-1.318	0.155	0.486
08	-0.618	-0.544	-0.019	0.642
09	-1.978	-0.49	-3.925	1.172
10	-6.529	1.385	-6.053	-6.894
11	-5.488	-2.339	-2.986	1.348
12	1.378	-4.097	-5.13	-4.658
13	-3.552	1.049	-4.305	0.099

Standard thresholds

P-value	Threshold
0.001	-1.69209
0.0005	0.25287
0.0001	4.286065